faculty

Rosana Risques

rrisques@uw.edu

University of Washington, 

Cancer Biology

Genetics, Genomics & Evolution

early cancer detection

Faculty Contact Information

Building: HSB Room: E506 Box: 357470 Phone: 206-616-4976 http://depts.washington.edu/risques/

Lab Information

Location: University of Washington Building: HSB Room: E506 Box: 357470 Phone: 206-221-8255 http://depts.washington.edu/risques/

Accepting Students For:

Rotation, Spring
Rotation, Summer
Rotation, Winter

Publications

All's well that ends well: why large species have short telomeres.

Risques RA, Promislow DEL.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2018; 373(1741).

PubMed [journal]
PMID:
29335372
PMCID:
PMC5784068

Precancer in ulcerative colitis: the role of the field effect and its clinical implications.

Baker KT, Salk JJ, Brentnall TA, Risques RA.

Carcinogenesis. 2018; 39(1):11-20.

PubMed [journal]
PMID:
29087436

Aging and the rise of somatic cancer-associated mutations in normal tissues.

Risques RA, Kennedy SR.

PLoS genetics. 2018; 14(1):e1007108.

PubMed [journal]
PMID:
29300727
PMCID:
PMC5754046

Magellanic penguin telomeres do not shorten with age with increased reproductive effort, investment, and basal corticosterone.

Cerchiara JA, Risques RA, Prunkard D, Smith JR, Kane OJ, Boersma PD.

Ecology and evolution. 2017; 7(15):5682-5691.

PubMed [journal]
PMID:
28811878
PMCID:
PMC5552965

Effect of heartfulness meditation on burnout, emotional wellness, and telomere length in health care professionals.

Thimmapuram J, Pargament R, Sibliss K, Grim R, Risques R, Toorens E.

Journal of community hospital internal medicine perspectives. 2017; 7(1):21-27.

PubMed [journal]
PMID:
28634520
PMCID:
PMC5463663

Research Summary

Research at the Risques Lab focuses on the development of biomarkers for early detection and prediction of cancer. We are especially interested in alterations that link cancer and aging including telomere shortening, mitochondrial dysfunction, and mutational load. Our main projects involve the application of novel molecular technologies, including NGS, to early cancer detection in the context of ulcerative colitis, an inflammatory bowel disease that predisposes to colorectal cancer. We also work on early detection of ovarian cancer by ultra-deep sequencing of liquid biopsies.