Qinghang (Chris) Liuqcliu@uw.edu
University of Washington,
Cell Signaling & Cell/Environment Interactions
Gene Expression, Cell Cycle & Chromosome Biology
Molecular Signaling Mechanisms of Cardiac Remodeling and Heart Failure
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Research in my lab is focused on defining novel signaling and transcriptional regulatory mechanisms that underlie cardiac hypertrophy and heart failure. We take multi-disciplinary approaches including biochemistry, molecular and cell biology, molecular genetics, and system physiology to understand the molecular basis of heart disease using model systems ranging from yeast cell system to genetic mouse models. There are 3 research areas: A.Molecular mechanisms of cardiac hypertrophy; B. Molecular regulation of cardiac cell survival and death; C.Programmed necrosis (necroptosis) in heart disease.