faculty

Christine Queitsch

queitsch@uw.edu

University of Washington, 

Cell Signaling & Cell/Environment Interactions

Gene Expression, Cell Cycle & Chromosome Biology

Genetics, Genomics & Evolution

Molecular mechanisms generating phenotypic variation and evolvability

Faculty Contact Information

Building: Foege South Room: S-410A Box: 355065 Phone: 206-685-8935 http://www.gs.washington.edu/faculty/queitsch.htm

Lab Information

Location: Department of Genome Sciences Building: Foege South Room: S-410 Box: 355065 Phone: 206-685-3776 http://queitschlab.gs.washington.edu/

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Publications

It's not magic - Hsp90 and its effects on genetic and epigenetic variation.

Zabinsky RA, Mason GA, Queitsch C, Jarosz DF.

Seminars in cell & developmental biology. 2018;

PubMed [journal]
PMID:
29807130

Complex Relationships between Chromatin Accessibility, Sequence Divergence, and Gene Expression in Arabidopsis thaliana.

Alexandre CM, Urton JR, Jean-Baptiste K, Huddleston J, Dorrity MW, Cuperus JT, Sullivan AM, Bemm F, Jolic D, Arsovski AA, Thompson A, Nemhauser JL, Fields S, Weigel D, Bubb KL, Queitsch C.

Molecular biology and evolution. 2018; 35(4):837-854.

PubMed [journal]
PMID:
29272536
PMCID:
PMC5889003

Profiling of Accessible Chromatin Regions across Multiple Plant Species and Cell Types Reveals Common Gene Regulatory Principles and New Control Modules.

Maher KA, Bajic M, Kajala K, Reynoso M, Pauluzzi G, West DA, Zumstein K, Woodhouse M, Bubb K, Dorrity MW, Queitsch C, Bailey-Serres J, Sinha N, Brady SM, Deal RB.

The Plant cell. 2018; 30(1):15-36.

PubMed [journal]
PMID:
29229750
PMCID:
PMC5810565

Variability in a Short Tandem Repeat Mediates Complex Epistatic Interactions in Arabidopsis thaliana.

Press MO, Queitsch C.

Genetics. 2017; 205(1):455-464.

PubMed [journal]
PMID:
27866166
PMCID:
PMC5223521

PIF4 and ELF3 Act Independently in Arabidopsis thaliana Thermoresponsive Flowering.

Press MO, Lanctot A, Queitsch C.

PloS one. 2016; 11(8):e0161791.

PubMed [journal]
PMID:
27564448
PMCID:
PMC5001698

Research Summary

We focus on the genetic architecture of complex traits and mechanisms and evolution of gene regulation. We ascertain uncharacterized sequence variation in plants and worms and resolve the relative importance of additive variation and epistasis in complex traits. We use genome-scale assays for mapping regulatory DNA, including enhancers, and chromosome conformation to explore newly discovered regulatory phenomena in plants, in addition to identifying potentially beneficial regulatory variation among plant strains and species. An important research focus is technology development.