faculty

Peter Myler

peter.myler@cidresearch.org

Center for Infectious Disease Research, 

Gene Expression, Cell Cycle & Chromosome Biology

Genetics, Genomics & Evolution

Microbiology, Infection & Immunity

Parasite Molecular Biology, Genomics And Bioinformatics

Faculty Contact Information

Phone: 206-256-7332

Lab Information

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Publications

The identification of inhibitory compounds of Rickettsia prowazekii methionine aminopeptidase for antibacterial applications.

Helgren TR, Seven ES, Chen C, Edwards TE, Staker BL, Abendroth J, Myler PJ, Horn JR, Hagen TJ.

Bioorganic & medicinal chemistry letters. 2018; 28(8):1376-1380. NIHMSID: NIHMS951902

PubMed [journal]
PMID:
29551481
PMCID:
PMC5908248

Crystal structure of chorismate mutase from Burkholderia thailandensis.

Asojo OA, Dranow DM, Serbzhinskiy D, Subramanian S, Staker B, Edwards TE, Myler PJ.

Acta crystallographica. Section F, Structural biology communications. 2018; 74(Pt 5):294-299.

PubMed [journal]
PMID:
29717997
PMCID:
PMC5931142

Crystal structure of chorismate mutase from Burkholderia phymatum.

Asojo OA, Subramanian S, Abendroth J, Exley I, Lorimer DD, Edwards TE, Myler PJ.

Acta crystallographica. Section F, Structural biology communications. 2018; 74(Pt 4):187-192.

PubMed [journal]
PMID:
29633965
PMCID:
PMC5894103

Mycobacterium tuberculosis Rv3651 is a triple sensor-domain protein.

Abendroth J, Frando A, Phan IQ, Staker BL, Myler PJ, Edwards TE, Grundner C.

Protein science : a publication of the Protein Society. 2018; 27(2):568-572.

PubMed [journal]
PMID:
29119630
PMCID:
PMC5775179

Disclosing 3' UTR cis-elements and putative partners involved in gene expression regulation in Leishmania spp.

TerrĂ£o MC, Rosas de Vasconcelos EJ, Defina TA, Myler PJ, Cruz AK.

PloS one. 2017; 12(8):e0183401.

PubMed [journal]
PMID:
28859096
PMCID:
PMC5578504

Research Summary

The Myler laboratory is devoted to discovery research aimed at developing novel therapeutic strategies against global infectious disease. Our work focuses on using genomic, bioinformatic, and molecular approaches to study gene and protein structure in bacterial, eukaryote and viral pathogens.