faculty

David Beier

david.beier@seattlechildrens.org

Seattle Childrens Research Institute, 

Developmental Biology, Stem Cells & Aging

Genetics, Genomics & Evolution

Developmental genetic analysis in model organisms.

Faculty Contact Information

Building: Jack MacDonald Building, 1900 9th Ave, Seattle, 98101 Room: 535 Phone: 206-884-1419

Lab Information

Location: Seattle Children's Research Institute Building: Jack MacDonald Building

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Research Summary

My research focuses on using genetic methods for the identification of genes causing human disease and developmental defects. We have positionally cloned the causal gene for over 50 mutations, many encoding previously uncharacterized genes. Our research has used many of the major tools in model organism analysis, including gene mapping and genomic analysis, characterization of modifying genes and QTLs, ENU mutagenesis for developmental investigation, SNP genotyping and next-gen sequencing for genetic mapping in the mouse and zebrafish, and genome-editing methods such as CRISPR.