faculty

Cecilia Moens

cmoens@fredhutch.org
Member

Fred Hutch

Basic Sciences

Cell Signaling & Cell/Environment Interactions

Developmental Biology, Stem Cells & Aging (Area Director)

Neuroscience

Nervous system development in zebrafish

Faculty Contact Information

Building: Weintraub Room: B2-159 Box: B2-159 Phone: 206-667-5627 Alt Phone: 206-667-5697 http://research.fhcrc.org/moens/en.html

Research Summary

The Moens lab studies the early development of the vertebrate brain, using the transparent zebrafish embryo as our in vivo model system. Our approaches combine genetics and in vivo imaging of neurons and neural progenitors in the process of neuroepithelial morphogenesis, neuronal migration and axogenesis with the goal of understanding how genes control the early events in the embryo that ultimately lead to the establishment of normal neural circuits.

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Publications

The following publications were retrieved from PubMed:

The generation of granule cells during the development and evolution of the cerebellum.

Iulianella A, Wingate RJ, Moens CB, Capaldo E.

Dev Dyn. 2019 Jul; 7(248)506-513

Microtubules are required for the maintenance of planar cell polarity in monociliated floorplate cells.

Mathewson AW, Berman DG, Moens CB.

Dev Biol. 2019 Aug 1; 1(452)21-33

Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis.

Poudel KR, Roh-Johnson M, Su A, Ho T, Mathsyaraja H, Anderson S, Grady WM, Moens CB, Conacci-Sorrell M, Eisenman RN, Bai J.

Dev Cell. 2018 Jun 18; 6(45)738-752.e6

Multiple zebrafish atoh1 genes specify a diversity of neuronal types in the zebrafish cerebellum.

Kidwell CU, Su CY, Hibi M, Moens CB.

Dev Biol. 2018 Jun 1; 1(438)44-56

Vagus Motor Neuron Topographic Map Determined by Parallel Mechanisms of hox5 Expression and Time of Axon Initiation.

Barsh GR, Isabella AJ, Moens CB.

Curr Biol. 2017 Dec 18; 24(27)3812-3825.e3

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Lab Information

Location: Fred Hutch
Building: Weintraub
Room: B2-123
Box: B2-159
Phone: 206-667-5697
Alt Phone: 206-667-5627 (office)
http://research.fhcrc.org/moens/en.html