David Fredricks


Fred Hutch, 

Genetics, Genomics & Evolution

Microbiology, Infection & Immunity

The human microbiome

Faculty Contact Information

Lab Information

Location: Fred Hutch Building: Eastlake Box: E4-100 http://research.fhcrc.org/fredricks/en.html

Accepting Students For:

Rotation, Spring
Rotation, Winter


The following publications were retrieved from PubMed:

The gut microbiota and graft-versus-host disease.

Fredricks DN

J Clin Invest. 2019 May 1; 5(129)1808-1817

Association between vaginal washing and detection of <i>Lactobacillus</i> by culture and quantitative PCR in HIV-seronegative Kenyan women: a cross-sectional analysis.

Lokken EM, Manguro GO, Abdallah A, Ngacha C, Shafi J, Kiarie J, Jaoko W, Srinivasan S, Fiedler TL, Munch MM, Fredricks DN, McClelland RS, Balkus JE.

Sex Transm Infect. 2019 Jan 29;

Association between vaginal washing and vaginal bacterial concentrations.

Sabo MC, Balkus JE, Richardson BA, Srinivasan S, Kimani J, Anzala O, Schwebke J, Feidler TL, Fredricks DN, McClelland RS.

PLoS One. 2019; 1(14)e0210825

The Evolving Facets of Bacterial Vaginosis: Implications for HIV Transmission.

McKinnon LR, Achilles SL, Bradshaw CS, Burgener A, Crucitti T, Fredricks DN, Jaspan HB, Kaul R, Kaushic C, Klatt N, Kwon DS, Marrazzo JM, Masson L, McClelland RS, Ravel J, van de Wijgert JHHM, Vodstrcil LA, Tachedjian G.

AIDS Res Hum Retroviruses. 2019 Mar; 3(35)219-228

Primary Syphilis in the Male Urethra - A Case Report.

Chambers LC, Srinivasan S, Lukehart SA, Ocbamichael N, Morgan JL, Lowens MS, Fredricks DN, Golden MR, Manhart LE.

Clin Infect Dis. 2018 Sep 10;

Research Summary

We study human associated microbial communities, including their composition, structure, dynamics and function. Our goal is to advance our understanding of how microbial populations in humans influence health and susceptibility to disease. Ongoing projects in the lab focus on the gut microbiome in patients with cancer and its connection with graft versus host disease and other outcomes in transplant recipients. We also study how the genital tract microbiota influences HIV infection, other sexually transmitted infections, preterm birth, and urethritis in men.