David Baker


University of Washington, 

Biophysical and Structural Biology

Protein structure prediction and design

Faculty Contact Information

Building: MolES Room: 442 Box: 351655 Phone: 206-543-1295 https://www.bakerlab.org/

Lab Information

Location: Institute for Protein Design Building: MolES Room: 4th floor Box: 351655 http://www.ipd.uw.edu/

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter

Research Summary

The goal of current research in our laboratory is to develop an improved model of intra and intermolecular interactions and to apply this improved model to the prediction and design of macromolecular structures and interactions using the Rosetta computer program. At the core of Rosetta are the physical model of macromolecular interactions and algorithms for finding the lowest energy structure for an amino acid sequence (protein structure prediction) or a protein-protein complex and for finding the lowest energy amino acid sequence for a protein or protein-protein complex (protein design).