University of Washington,
Biophysical and Structural Biology
Protein structure prediction and design
Faculty Contact Information
Accepting Students For:
The goal of current research in our laboratory is to develop an improved model of intra and intermolecular interactions and to apply this improved model to the prediction and design of macromolecular structures and interactions using the Rosetta computer program. At the core of Rosetta are the physical model of macromolecular interactions and algorithms for finding the lowest energy structure for an amino acid sequence (protein structure prediction) or a protein-protein complex and for finding the lowest energy amino acid sequence for a protein or protein-protein complex (protein design).