William M. Grady


Fred Hutch, 

Cancer Biology

Cell Signaling & Cell/Environment Interactions

Gene Expression, Cell Cycle & Chromosome Biology

Molecular and cell biology of gastrointestinal cancer and Cancer epigenetics

Faculty Contact Information

Building: Thomas Building Room: D4-108 Phone: 206-667-1107

Lab Information

Location: Fred Hutchinson Cancer Research Center Building: Thomas Building Room: D4-255 Box: D4-100 Phone: 206-667-1987 https://research.fhcrc.org/grady/en/research.html

Accepting Students For:

Rotation, Spring
Rotation, Winter

Research Summary

The Grady lab studies the molecular pathogenesis of gastrointestinal cancer, with areas of focus on the the study of mutations and epigenetic alterations in driving cancer formation and on the role of cancer epigenetics in the initiation and progression of tumors. We use a variety of cutting-edge approaches (organoid cultures, methylation arrays, droplet digital PCR, next-generation sequencing, bisulfite sequencing, organoid cultures, CRISPR-Cas9, etc)in different model systems and primary tissues in order to discover the functional role of molecular alterations in the tumorigenesis process.