faculty

Toshio Tsukiyama

ttsukiya@fredhutch.org
Professor

Fred Hutch

, 

Basic Sciences

Gene Expression, Cell Cycle & Chromosome Biology (Area Director)

chromatin regulation for cell division and cell-cycle control

Faculty Contact Information

Building: A1 Room: A1-175 Box: A1-162 Phone: 206-667-4996 http://research.fhcrc.org/tsukiyama/en.html

Research Summary

In eukaryotic cells, DNA is packaged into chromatin, which allows compact storage of the genome, but limits the access of DNA binding proteins to their targets. As a result, chromatin structure affects virtually all DNA-dependent processes and chromatin regulators are frequently mutated in cancer. However, how chromatin regulation affects cell division and cell-cycle is not well unserstood. We are especially interested in cell quiescence, and are investigating how chromatin regulation affects the entry, maintenance and exit from quiescence.

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&query_key=1&WebEnv=MCID_60115be737cccf3e9531341b&retmode=json
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Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Lab Information

Location: Fred Hutchinson Cancer Research Center
Building: A1
Room: A1-175
Box: A1-162
Phone: 206-667-4996
http://research.fhcrc.org/tsukiyama/en.html