Akhila Rajan

Assistant Professor

Fred Hutch

Basic Sciences

Cell Signaling & Cell/Environment Interactions

Gene Expression, Cell Cycle & Chromosome Biology


Impact of obesity on immunity and cognition

Faculty Contact Information

Building: Weintraub Building Room: B2 163 Box: A2 025 http://akhilalab.org/

Research Summary

We investigate how fat stores communicate with the brain to control physiology. Our inquiries have led us to unexpected and fundamental discoveries in the realms of both cell biology [how nutrient state regulates nucleocytoplasmic localization of fat hormones/adipokines] and neurobiology [how adipokines influence synapse number to maintain body weight]. Active ongoing projects: i) how fat cells package adipokines for delivery to the brain; ii) elucidate interactions between fat stores and innate immune axes; iii) uncover how adipokine localization controls hunger-driven feeding motivation.

DEI Statement

At the Rajan Lab, we believe that everyone should have equal opportunity to learn and explore so that they may realize themselves to their fullest potential. We believe in diversity and inclusion, since the challenges facing humanity, are beyond a single individual and will require the coming together of all peoples of different perspectives and backgrounds to work collectively toward solutions.

Training Summary

Bias Mitigation Education: Grounding & Commitment module (BME-1)

Helping Your Trainees Develop Resilience (Offered by Sharon Milgram NIH-OITE)

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Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter

Lab Information

Location: Fred Hutch
Building: Weintraub
Room: B2 183
Box: MS A2 025