Akhila Rajan

Assistant Professor

Fred Hutch

Basic Sciences

Cell Signaling & Cell/Environment Interactions (Area Director)

Gene Expression, Cell Cycle & Chromosome Biology


Impact of obesity on immunity and cognition

Faculty Contact Information

Building: Weintraub Building Room: B2 163 Box: A2 025 http://akhilalab.org/

Research Summary

We investigate how fat stores communicate with the brain to control physiology. Our inquiries have led us to unexpected and fundamental discoveries in the realms of both cell biology [how nutrient state regulates nucleocytoplasmic localization of fat hormones/adipokines] and neurobiology [how adipokines influence synapse number to maintain body weight]. Active ongoing projects: i) how fat cells package adipokines for delivery to the brain; ii) elucidate interactions between fat stores and innate immune axes; iii) uncover how adipokine localization controls hunger-driven feeding motivation.

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Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter

Lab Information

Location: Fred Hutch
Building: Weintraub
Room: B2 183
Box: MS A2 025