Cell Signaling & Cell/Environment Interactions (Area Director)
Microbiology, Infection & Immunity
How fat stores impact cognition, immunity and behavior
Faculty Contact Information
My lab studies how fat stores impact cognition, immunity and behavior. In the past 4 years, we uncovered how fat cells regulates adipokine secretion. We discovered a mechanism in fat cells to couple adipokine secretion to its nucleocytoplasmic localization. In parallel studies, we also elucidated how adipokines inhibit target neurons to maintain body weight. Now, we address: i) how fat cells package adipokines for delivery to the brain; ii) how protein localization in fat cells is regulated by nutrient state; iii) how fat interfaces with and impacts innate immunity.
Accepting Students For:
Room: B2 183
Box: MS A2 025