Akhila Rajan

Assistant Professor

Fred Hutch

Basic Sciences

Cell Signaling & Cell/Environment Interactions (Area Director)

Microbiology, Infection & Immunity


How fat stores impact cognition, immunity and behavior

Faculty Contact Information

Building: Weintraub Building Room: B2 163 Box: A2 025 http://akhilalab.org/

Research Summary

My lab studies how fat stores impact cognition, immunity and behavior. In the past 4 years, we uncovered how fat cells regulates adipokine secretion. We discovered a mechanism in fat cells to couple adipokine secretion to its nucleocytoplasmic localization. In parallel studies, we also elucidated how adipokines inhibit target neurons to maintain body weight. Now, we address: i) how fat cells package adipokines for delivery to the brain; ii) how protein localization in fat cells is regulated by nutrient state; iii) how fat interfaces with and impacts innate immunity.

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Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter

Lab Information

Location: Fred Hutch
Building: Weintraub
Room: B2 183
Box: MS A2 025