faculty

Lucas Sullivan

lucas@fredhutch.org
Assistant Member

Fred Hutch

Human Biology

Cancer Biology

Cell Signaling & Cell/Environment Interactions

Developmental Biology, Stem Cells & Aging

Understanding metabolic constraints of cell proliferation

Faculty Contact Information

Building: Hutchinson Room: C3-159 Box: c3-168 Phone: 206-667-7826

Research Summary

My lab broadly seeks to understand how metabolism is used to support cell function. One example is to determine the metabolic pathways particularly required for cancer growth and progression, with a goal to identify new targets for cancer therapy. We use mass spectrometry, isotope tracing, metabolomics, and cancer models to understand several themes in metabolism including the role of metabolic pathways in supporting cell proliferation, the network effects of physiologically relevant perturbations to cell metabolism, and discovery of new metabolic products and pathways.

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&query_key=1&WebEnv=NCID_1_168498146_130.14.18.48_9001_1569069446_2117944708_0MetA0_S_MegaStore&retmode=json
Resource id #555 -- array(2) { ["header"]=> array(2) { ["type"]=> string(8) "esummary" ["version"]=> string(3) "0.3" } ["result"]=> array(22) { ["uids"]=> array(21) { [0]=> string(8) "30193108" [1]=> string(8) "29941931" [2]=> string(8) "29227471" [3]=> string(8) "28820875" [4]=> string(8) "27658530" [5]=> string(8) "27746050" [6]=> string(8) "27434767" [7]=> string(8) "27110680" [8]=> string(8) "27058668" [9]=> string(8) "26919427" [10]=> string(8) "26880201" [11]=> string(8) "26853747" [12]=> string(8) "26232225" [13]=> string(8) "25671107" [14]=> string(8) "25347702" [15]=> string(8) "24857658" [16]=> string(8) "24843020" [17]=> string(8) "24335489" [18]=> string(8) "23747014" [19]=> string(8) "23020852" [20]=> string(8) "22101431" } [30193108]=> array(43) { ["uid"]=> string(8) "30193108" ["pubdate"]=> string(10) "2018 Sep 6" ["epubdate"]=> string(0) "" ["source"]=> string(4) "Cell" ["authors"]=> array(1) { [0]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(11) "Sullivan LB" ["title"]=> string(60) "Metabolic Frugality Marks Cancer Cells for Immune Targeting." ["sorttitle"]=> string(59) "metabolic frugality marks cancer cells for immune targeting" ["volume"]=> string(3) "174" ["issue"]=> string(1) "6" ["pages"]=> string(9) "1344-1346" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0413066" ["issn"]=> string(9) "0092-8674" ["essn"]=> string(9) "1097-4172" ["pubtype"]=> array(2) { [0]=> string(7) "Comment" [1]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(5) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "30193108" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S0092-8674(18)31039-0" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(26) "10.1016/j.cell.2018.08.023" } [3]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "30193108" } [4]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "30193108" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2018/09/08 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2018/09/08 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2019/05/14 06:00" } } ["references"]=> array(1) { [0]=> array(4) { ["refsource"]=> string(37) "Cell. 2018 Sep 6;174(6):1559-1570.e22" ["reftype"]=> string(10) "Comment on" ["pmid"]=> int(30100185) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(1) ["fulljournalname"]=> string(4) "Cell" ["elocationid"]=> string(31) "doi: 10.1016/j.cell.2018.08.023" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2018/09/06 00:00" ["sortfirstauthor"]=> string(11) "Sullivan LB" ["vernaculartitle"]=> string(0) "" } [29941931]=> array(43) { ["uid"]=> string(8) "29941931" ["pubdate"]=> string(8) "2018 Jul" ["epubdate"]=> string(11) "2018 Jun 25" ["source"]=> string(13) "Nat Cell Biol" ["authors"]=> array(11) { [0]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(8) "Luengo A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(8) "Danai LV" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(7) "Bush LN" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(8) "Diehl FF" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(9) "Hosios AM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(6) "Lau AN" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(10) "Elmiligy S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(10) "Malstrom S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(8) "Lewis CA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(16) "Vander Heiden MG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(16) "Vander Heiden MG" ["title"]=> string(66) "Aspartate is an endogenous metabolic limitation for tumour growth." ["sorttitle"]=> string(65) "aspartate is an endogenous metabolic limitation for tumour growth" ["volume"]=> string(2) "20" ["issue"]=> string(1) "7" ["pages"]=> string(7) "782-788" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "100890575" ["issn"]=> string(9) "1465-7392" ["essn"]=> string(9) "1476-4679" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "29941931" } [1]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(25) "10.1038/s41556-018-0125-0" } [2]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(25) "10.1038/s41556-018-0125-0" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC6051729" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(11) "NIHMS969303" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "29941931" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "29941931" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(46) "pmc-id: PMC6051729;manuscript-id: NIHMS969303;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2018/02/15 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2018/05/18 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2018/06/27 06:00" } [3]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2019/04/10 06:00" } [4]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2018/06/27 06:00" } } ["references"]=> array(1) { [0]=> array(4) { ["refsource"]=> string(37) "Nat Cell Biol. 2018 Jul;20(7):738-739" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(29941932) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(21) ["fulljournalname"]=> string(19) "Nature cell biology" ["elocationid"]=> string(30) "doi: 10.1038/s41556-018-0125-0" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2018/07/01 00:00" ["sortfirstauthor"]=> string(11) "Sullivan LB" ["vernaculartitle"]=> string(0) "" } [29227471]=> array(43) { ["uid"]=> string(8) "29227471" ["pubdate"]=> string(8) "2018 Feb" ["epubdate"]=> string(11) "2017 Dec 11" ["source"]=> string(13) "Nat Chem Biol" ["authors"]=> array(10) { [0]=> array(3) { ["name"]=> string(11) "McLellan CA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(10) "Vincent BM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(8) "Solis NV" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(12) "Lancaster AK" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(11) "Hartland CL" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(11) "Youngsaye W" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(9) "Filler SG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(11) "Whitesell L" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(11) "Lindquist S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(11) "Lindquist S" ["title"]=> string(83) "Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy." ["sorttitle"]=> string(82) "inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy" ["volume"]=> string(2) "14" ["issue"]=> string(1) "2" ["pages"]=> string(7) "135-141" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101231976" ["issn"]=> string(9) "1552-4450" ["essn"]=> string(9) "1552-4469" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "29227471" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(13) "nchembio.2534" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(21) "10.1038/nchembio.2534" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC5771894" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(11) "NIHMS916444" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "29227471" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "29227471" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(46) "pmc-id: PMC5771894;manuscript-id: NIHMS916444;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2017/06/01 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2017/10/27 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2017/12/12 06:00" } [3]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2019/05/06 06:00" } [4]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2017/12/12 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(1) ["fulljournalname"]=> string(23) "Nature chemical biology" ["elocationid"]=> string(26) "doi: 10.1038/nchembio.2534" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2018/02/01 00:00" ["sortfirstauthor"]=> string(11) "McLellan CA" ["vernaculartitle"]=> string(0) "" } [28820875]=> array(43) { ["uid"]=> string(8) "28820875" ["pubdate"]=> string(11) "2017 Aug 18" ["epubdate"]=> string(0) "" ["source"]=> string(13) "Nat Chem Biol" ["authors"]=> array(1) { [0]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(11) "Sullivan LB" ["title"]=> string(54) "Extracellular vesicles: Taking metabolism on the road." ["sorttitle"]=> string(52) "extracellular vesicles taking metabolism on the road" ["volume"]=> string(2) "13" ["issue"]=> string(1) "9" ["pages"]=> string(7) "924-925" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101231976" ["issn"]=> string(9) "1552-4450" ["essn"]=> string(9) "1552-4469" ["pubtype"]=> array(2) { [0]=> string(7) "Comment" [1]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(5) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "28820875" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(13) "nchembio.2455" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(21) "10.1038/nchembio.2455" } [3]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "28820875" } [4]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "28820875" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2017/08/19 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2017/08/19 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2019/09/20 06:00" } } ["references"]=> array(1) { [0]=> array(4) { ["refsource"]=> string(37) "Nat Chem Biol. 2017 Sep;13(9):951-955" ["reftype"]=> string(10) "Comment on" ["pmid"]=> int(28671681) ["note"]=> string(0) "" } } ["attributes"]=> array(0) { } ["pmcrefcount"]=> int(2) ["fulljournalname"]=> string(23) "Nature chemical biology" ["elocationid"]=> string(26) "doi: 10.1038/nchembio.2455" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2017/08/18 00:00" ["sortfirstauthor"]=> string(11) "Sullivan LB" ["vernaculartitle"]=> string(0) "" } [27658530]=> array(43) { ["uid"]=> string(8) "27658530" ["pubdate"]=> string(8) "2016 Nov" ["epubdate"]=> string(11) "2016 Sep 23" ["source"]=> string(14) "Nat Rev Cancer" ["authors"]=> array(3) { [0]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(6) "Gui DY" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(16) "Vander Heiden MG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(16) "Vander Heiden MG" ["title"]=> string(88) "Altered metabolite levels in cancer: implications for tumour biology and cancer therapy." ["sorttitle"]=> string(86) "altered metabolite levels in cancer implications for tumour biology and cancer therapy" ["volume"]=> string(2) "16" ["issue"]=> string(2) "11" ["pages"]=> string(7) "680-693" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101124168" ["issn"]=> string(9) "1474-175X" ["essn"]=> string(9) "1474-1768" ["pubtype"]=> array(2) { [0]=> string(15) "Journal Article" [1]=> string(6) "Review" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(5) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "27658530" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(11) "nrc.2016.85" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(19) "10.1038/nrc.2016.85" } [3]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "27658530" } [4]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "27658530" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2016/10/25 06:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2017/05/17 06:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2016/09/24 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(41) ["fulljournalname"]=> string(22) "Nature reviews. Cancer" ["elocationid"]=> string(24) "doi: 10.1038/nrc.2016.85" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2016/11/01 00:00" ["sortfirstauthor"]=> string(11) "Sullivan LB" ["vernaculartitle"]=> string(0) "" } [27746050]=> array(43) { ["uid"]=> string(8) "27746050" ["pubdate"]=> string(10) "2016 Nov 8" ["epubdate"]=> string(11) "2016 Oct 13" ["source"]=> string(10) "Cell Metab" ["authors"]=> array(10) { [0]=> array(3) { ["name"]=> string(6) "Gui DY" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(8) "Luengo A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(9) "Hosios AM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(7) "Bush LN" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(8) "Gitego N" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(11) "Davidson SM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(11) "Freinkman E" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(9) "Thomas CJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(16) "Vander Heiden MG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(16) "Vander Heiden MG" ["title"]=> string(145) "Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin." ["sorttitle"]=> string(143) "environment dictates dependence on mitochondrial complex i for nad and aspartate production and determines cancer cell sensitivity to metformin" ["volume"]=> string(2) "24" ["issue"]=> string(1) "5" ["pages"]=> string(7) "716-727" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101233170" ["issn"]=> string(9) "1550-4131" ["essn"]=> string(9) "1932-7420" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "27746050" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S1550-4131(16)30484-3" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(26) "10.1016/j.cmet.2016.09.006" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC5102768" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(11) "NIHMS817830" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "27746050" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "27746050" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(46) "pmc-id: PMC5102768;manuscript-id: NIHMS817830;" } } ["history"]=> array(6) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2015/08/24 00:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "revised" ["date"]=> string(16) "2016/07/26 00:00" } [2]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2016/09/14 00:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2016/10/18 06:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2017/06/27 06:00" } [5]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2016/10/18 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(49) ["fulljournalname"]=> string(15) "Cell metabolism" ["elocationid"]=> string(31) "doi: 10.1016/j.cmet.2016.09.006" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2016/11/08 00:00" ["sortfirstauthor"]=> string(6) "Gui DY" ["vernaculartitle"]=> string(0) "" } [27434767]=> array(43) { ["uid"]=> string(8) "27434767" ["pubdate"]=> string(11) "2016 Jul 19" ["epubdate"]=> string(0) "" ["source"]=> string(13) "Nat Chem Biol" ["authors"]=> array(32) { [0]=> array(3) { ["name"]=> string(9) "Pacold ME" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(13) "Brimacombe KR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(7) "Chan SH" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(8) "Rohde JM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(8) "Lewis CA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(8) "Swier LJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(11) "Possemato R" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(7) "Chen WW" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(8) "Fiske BP" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(5) "Cho S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [11]=> array(3) { ["name"]=> string(11) "Freinkman E" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [12]=> array(3) { ["name"]=> string(8) "Birsoy K" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [13]=> array(3) { ["name"]=> string(6) "Abu MR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [14]=> array(3) { ["name"]=> string(8) "Shaul YD" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [15]=> array(3) { ["name"]=> string(6) "Liu CM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [16]=> array(3) { ["name"]=> string(6) "Zhou M" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [17]=> array(3) { ["name"]=> string(6) "Koh MJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [18]=> array(3) { ["name"]=> string(7) "Chung H" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [19]=> array(3) { ["name"]=> string(11) "Davidson SM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [20]=> array(3) { ["name"]=> string(8) "Luengo A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [21]=> array(3) { ["name"]=> string(7) "Wang AQ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [22]=> array(3) { ["name"]=> string(4) "Xu X" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [23]=> array(3) { ["name"]=> string(8) "Yasgar A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [24]=> array(3) { ["name"]=> string(5) "Liu L" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [25]=> array(3) { ["name"]=> string(5) "Rai G" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [26]=> array(3) { ["name"]=> string(11) "Westover KD" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [27]=> array(3) { ["name"]=> string(9) "Heiden MG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [28]=> array(3) { ["name"]=> string(6) "Shen M" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [29]=> array(3) { ["name"]=> string(7) "Gray NS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [30]=> array(3) { ["name"]=> string(8) "Boxer MB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [31]=> array(3) { ["name"]=> string(11) "Sabatini DM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(11) "Sabatini DM" ["title"]=> string(97) "Corrigendum: A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate." ["sorttitle"]=> string(95) "corrigendum a phgdh inhibitor reveals coordination of serine synthesis and one carbon unit fate" ["volume"]=> string(2) "12" ["issue"]=> string(1) "8" ["pages"]=> string(3) "656" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101231976" ["issn"]=> string(9) "1552-4450" ["essn"]=> string(9) "1552-4469" ["pubtype"]=> array(2) { [0]=> string(15) "Journal Article" [1]=> string(17) "Published Erratum" } ["recordstatus"]=> string(6) "PubMed" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(5) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "27434767" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(16) "nchembio0816-656" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(24) "10.1038/nchembio0816-656" } [3]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "27434767" } [4]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "27434767" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2016/07/20 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2016/07/21 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2016/07/21 06:01" } } ["references"]=> array(1) { [0]=> array(4) { ["refsource"]=> string(36) "Nat Chem Biol. 2016 Jun;12 (6):452-8" ["reftype"]=> string(11) "Erratum for" ["pmid"]=> int(27110680) ["note"]=> string(0) "" } } ["attributes"]=> array(0) { } ["pmcrefcount"]=> int(4) ["fulljournalname"]=> string(23) "Nature chemical biology" ["elocationid"]=> string(29) "doi: 10.1038/nchembio0816-656" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2016/07/19 00:00" ["sortfirstauthor"]=> string(9) "Pacold ME" ["vernaculartitle"]=> string(0) "" } [27110680]=> array(43) { ["uid"]=> string(8) "27110680" ["pubdate"]=> string(8) "2016 Jun" ["epubdate"]=> string(11) "2016 Apr 25" ["source"]=> string(13) "Nat Chem Biol" ["authors"]=> array(32) { [0]=> array(3) { ["name"]=> string(9) "Pacold ME" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(13) "Brimacombe KR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(7) "Chan SH" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(8) "Rohde JM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(8) "Lewis CA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(8) "Swier LJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(11) "Possemato R" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(7) "Chen WW" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(8) "Fiske BP" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(5) "Cho S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [11]=> array(3) { ["name"]=> string(11) "Freinkman E" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [12]=> array(3) { ["name"]=> string(8) "Birsoy K" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [13]=> array(3) { ["name"]=> string(14) "Abu-Remaileh M" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [14]=> array(3) { ["name"]=> string(8) "Shaul YD" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [15]=> array(3) { ["name"]=> string(6) "Liu CM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [16]=> array(3) { ["name"]=> string(6) "Zhou M" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [17]=> array(3) { ["name"]=> string(6) "Koh MJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [18]=> array(3) { ["name"]=> string(7) "Chung H" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [19]=> array(3) { ["name"]=> string(11) "Davidson SM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [20]=> array(3) { ["name"]=> string(8) "Luengo A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [21]=> array(3) { ["name"]=> string(7) "Wang AQ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [22]=> array(3) { ["name"]=> string(4) "Xu X" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [23]=> array(3) { ["name"]=> string(8) "Yasgar A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [24]=> array(3) { ["name"]=> string(5) "Liu L" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [25]=> array(3) { ["name"]=> string(5) "Rai G" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [26]=> array(3) { ["name"]=> string(11) "Westover KD" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [27]=> array(3) { ["name"]=> string(16) "Vander Heiden MG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [28]=> array(3) { ["name"]=> string(6) "Shen M" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [29]=> array(3) { ["name"]=> string(7) "Gray NS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [30]=> array(3) { ["name"]=> string(8) "Boxer MB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [31]=> array(3) { ["name"]=> string(11) "Sabatini DM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(11) "Sabatini DM" ["title"]=> string(84) "A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate." ["sorttitle"]=> string(81) "phgdh inhibitor reveals coordination of serine synthesis and one carbon unit fate" ["volume"]=> string(2) "12" ["issue"]=> string(1) "6" ["pages"]=> string(5) "452-8" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101231976" ["issn"]=> string(9) "1552-4450" ["essn"]=> string(9) "1552-4469" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "27110680" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(13) "nchembio.2070" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(21) "10.1038/nchembio.2070" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC4871733" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(11) "NIHMS772725" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "27110680" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "27110680" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(46) "pmc-id: PMC4871733;manuscript-id: NIHMS772725;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2015/12/16 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2016/03/24 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2016/04/26 06:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2016/04/26 06:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2017/05/04 06:00" } } ["references"]=> array(2) { [0]=> array(4) { ["refsource"]=> string(39) "Nat Chem Biol. 2016 May 18;12(6):389-90" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(27191646) ["note"]=> string(0) "" } [1]=> array(4) { ["refsource"]=> string(37) "Nat Chem Biol. 2016 Jul 19;12 (8):656" ["reftype"]=> string(10) "Erratum in" ["pmid"]=> int(27434767) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(62) ["fulljournalname"]=> string(23) "Nature chemical biology" ["elocationid"]=> string(26) "doi: 10.1038/nchembio.2070" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2016/06/01 00:00" ["sortfirstauthor"]=> string(9) "Pacold ME" ["vernaculartitle"]=> string(0) "" } [27058668]=> array(43) { ["uid"]=> string(8) "27058668" ["pubdate"]=> string(10) "2016 Apr 7" ["epubdate"]=> string(0) "" ["source"]=> string(4) "Cell" ["authors"]=> array(16) { [0]=> array(3) { ["name"]=> string(12) "Olenchock BA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(9) "Moslehi J" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(7) "Baik AH" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(11) "Davidson SM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(10) "Williams J" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(9) "Gibson WJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(14) "Chakraborty AA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(9) "Pierce KA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(9) "Miller CM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(8) "Hanse EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(9) "Kelekar A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [11]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [12]=> array(3) { ["name"]=> string(9) "Wagers AJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [13]=> array(3) { ["name"]=> string(8) "Clish CB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [14]=> array(3) { ["name"]=> string(16) "Vander Heiden MG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [15]=> array(3) { ["name"]=> string(12) "Kaelin WG Jr" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(12) "Kaelin WG Jr" ["title"]=> string(90) "EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection." ["sorttitle"]=> string(86) "egln1 inhibition and rerouting of ketoglutarate suffice for remote ischemic protection" ["volume"]=> string(3) "165" ["issue"]=> string(1) "2" ["pages"]=> string(3) "497" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0413066" ["issn"]=> string(9) "0092-8674" ["essn"]=> string(9) "1097-4172" ["pubtype"]=> array(1) { [0]=> string(17) "Published Erratum" } ["recordstatus"]=> string(6) "PubMed" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(5) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "27058668" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S0092-8674(16)30335-X" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(26) "10.1016/j.cell.2016.03.037" } [3]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "27058668" } [4]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "27058668" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2016/04/09 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2016/04/09 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2016/04/09 06:01" } } ["references"]=> array(1) { [0]=> array(4) { ["refsource"]=> string(31) "Cell. 2016 Feb 25;164(5):884-95" ["reftype"]=> string(11) "Erratum for" ["pmid"]=> int(26919427) ["note"]=> string(0) "" } } ["attributes"]=> array(0) { } ["pmcrefcount"]=> int(4) ["fulljournalname"]=> string(4) "Cell" ["elocationid"]=> string(31) "doi: 10.1016/j.cell.2016.03.037" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2016/04/07 00:00" ["sortfirstauthor"]=> string(12) "Olenchock BA" ["vernaculartitle"]=> string(0) "" } [26919427]=> array(43) { ["uid"]=> string(8) "26919427" ["pubdate"]=> string(11) "2016 Feb 25" ["epubdate"]=> string(0) "" ["source"]=> string(4) "Cell" ["authors"]=> array(16) { [0]=> array(3) { ["name"]=> string(12) "Olenchock BA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(9) "Moslehi J" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(7) "Baik AH" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(11) "Davidson SM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(10) "Williams J" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(9) "Gibson WJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(14) "Chakraborty AA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(9) "Pierce KA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(9) "Miller CM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(8) "Hanse EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(9) "Kelekar A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [11]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [12]=> array(3) { ["name"]=> string(9) "Wagers AJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [13]=> array(3) { ["name"]=> string(8) "Clish CB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [14]=> array(3) { ["name"]=> string(16) "Vander Heiden MG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [15]=> array(3) { ["name"]=> string(12) "Kaelin WG Jr" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(12) "Kaelin WG Jr" ["title"]=> string(90) "EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection." ["sorttitle"]=> string(86) "egln1 inhibition and rerouting of ketoglutarate suffice for remote ischemic protection" ["volume"]=> string(3) "164" ["issue"]=> string(1) "5" ["pages"]=> string(6) "884-95" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0413066" ["issn"]=> string(9) "0092-8674" ["essn"]=> string(9) "1097-4172" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "26919427" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S0092-8674(16)30072-1" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(26) "10.1016/j.cell.2016.02.006" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC4819986" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(11) "NIHMS761410" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "26919427" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "26919427" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(71) "pmc-id: PMC4819986;manuscript-id: NIHMS761410;embargo-date: 2017/02/25;" } } ["history"]=> array(7) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2015/08/10 00:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "revised" ["date"]=> string(16) "2015/12/12 00:00" } [2]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2016/02/01 00:00" } [3]=> array(2) { ["pubstatus"]=> string(11) "pmc-release" ["date"]=> string(16) "2017/02/25 00:00" } [4]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2016/02/27 06:00" } [5]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2016/02/27 06:00" } [6]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2016/07/28 06:00" } } ["references"]=> array(1) { [0]=> array(4) { ["refsource"]=> string(27) "Cell. 2016 Apr 7;165(2):497" ["reftype"]=> string(10) "Erratum in" ["pmid"]=> int(27058668) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(28) ["fulljournalname"]=> string(4) "Cell" ["elocationid"]=> string(31) "doi: 10.1016/j.cell.2016.02.006" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2016/02/25 00:00" ["sortfirstauthor"]=> string(12) "Olenchock BA" ["vernaculartitle"]=> string(0) "" } [26880201]=> array(43) { ["uid"]=> string(8) "26880201" ["pubdate"]=> string(11) "2016 Feb 15" ["epubdate"]=> string(0) "" ["source"]=> string(11) "J Cell Biol" ["authors"]=> array(11) { [0]=> array(3) { ["name"]=> string(8) "Hecht VC" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(13) "Kimmerling RJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(6) "Kim DH" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(9) "Hosios AM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(14) "Stockslager MA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(10) "Stevens MM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(7) "Kang JH" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(7) "Wirtz D" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(16) "Vander Heiden MG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(10) "Manalis SR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(10) "Manalis SR" ["title"]=> string(82) "Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes." ["sorttitle"]=> string(81) "biophysical changes reduce energetic demand in growth factor deprived lymphocytes" ["volume"]=> string(3) "212" ["issue"]=> string(1) "4" ["pages"]=> string(6) "439-47" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0375356" ["issn"]=> string(9) "0021-9525" ["essn"]=> string(9) "1540-8140" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "26880201" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(13) "jcb.201506118" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(21) "10.1083/jcb.201506118" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC4754715" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "26880201" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "26880201" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC4754715;" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2016/02/17 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2016/02/18 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2016/08/02 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(7) ["fulljournalname"]=> string(27) "The Journal of cell biology" ["elocationid"]=> string(26) "doi: 10.1083/jcb.201506118" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2016/02/15 00:00" ["sortfirstauthor"]=> string(8) "Hecht VC" ["vernaculartitle"]=> string(0) "" } [26853747]=> array(43) { ["uid"]=> string(8) "26853747" ["pubdate"]=> string(10) "2016 Mar 8" ["epubdate"]=> string(10) "2016 Feb 4" ["source"]=> string(10) "Cell Metab" ["authors"]=> array(20) { [0]=> array(3) { ["name"]=> string(11) "Davidson SM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(20) "Papagiannakopoulos T" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(12) "Olenchock BA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(9) "Heyman JE" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(10) "Keibler MA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(8) "Luengo A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(8) "Bauer MR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(6) "Jha AK" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(10) "O'Brien JP" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(9) "Pierce KA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(6) "Gui DY" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [11]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [12]=> array(3) { ["name"]=> string(12) "Wasylenko TM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [13]=> array(3) { ["name"]=> string(10) "Subbaraj L" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [14]=> array(3) { ["name"]=> string(7) "Chin CR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [15]=> array(3) { ["name"]=> string(16) "Stephanopolous G" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [16]=> array(3) { ["name"]=> string(7) "Mott BT" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [17]=> array(3) { ["name"]=> string(7) "Jacks T" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [18]=> array(3) { ["name"]=> string(8) "Clish CB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [19]=> array(3) { ["name"]=> string(16) "Vander Heiden MG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(16) "Vander Heiden MG" ["title"]=> string(88) "Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer." ["sorttitle"]=> string(87) "environment impacts the metabolic dependencies of ras driven non small cell lung cancer" ["volume"]=> string(2) "23" ["issue"]=> string(1) "3" ["pages"]=> string(6) "517-28" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101233170" ["issn"]=> string(9) "1550-4131" ["essn"]=> string(9) "1932-7420" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "26853747" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S1550-4131(16)00041-3" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(26) "10.1016/j.cmet.2016.01.007" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC4785096" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(11) "NIHMS758714" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "26853747" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "26853747" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(46) "pmc-id: PMC4785096;manuscript-id: NIHMS758714;" } } ["history"]=> array(6) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2015/07/14 00:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "revised" ["date"]=> string(16) "2015/11/16 00:00" } [2]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2016/01/06 00:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2016/02/09 06:00" } [4]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2016/02/09 06:00" } [5]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2016/12/15 06:00" } } ["references"]=> array(1) { [0]=> array(4) { ["refsource"]=> string(34) "Nat Rev Cancer. 2016 Apr;16(4):198" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(27009387) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(150) ["fulljournalname"]=> string(15) "Cell metabolism" ["elocationid"]=> string(31) "doi: 10.1016/j.cmet.2016.01.007" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2016/03/08 00:00" ["sortfirstauthor"]=> string(11) "Davidson SM" ["vernaculartitle"]=> string(0) "" } [26232225]=> array(43) { ["uid"]=> string(8) "26232225" ["pubdate"]=> string(11) "2015 Jul 30" ["epubdate"]=> string(0) "" ["source"]=> string(4) "Cell" ["authors"]=> array(6) { [0]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(6) "Gui DY" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(9) "Hosios AM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(7) "Bush LN" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(11) "Freinkman E" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(16) "Vander Heiden MG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(16) "Vander Heiden MG" ["title"]=> string(97) "Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells." ["sorttitle"]=> string(96) "supporting aspartate biosynthesis is an essential function of respiration in proliferating cells" ["volume"]=> string(3) "162" ["issue"]=> string(1) "3" ["pages"]=> string(6) "552-63" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0413066" ["issn"]=> string(9) "0092-8674" ["essn"]=> string(9) "1097-4172" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "26232225" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S0092-8674(15)00854-5" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(26) "10.1016/j.cell.2015.07.017" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC4522278" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(11) "NIHMS709568" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "26232225" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "26232225" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(46) "pmc-id: PMC4522278;manuscript-id: NIHMS709568;" } } ["history"]=> array(6) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2015/06/08 00:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "revised" ["date"]=> string(16) "2015/07/06 00:00" } [2]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2015/07/08 00:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2015/08/02 06:00" } [4]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2015/08/02 06:00" } [5]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2015/10/29 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(181) ["fulljournalname"]=> string(4) "Cell" ["elocationid"]=> string(31) "doi: 10.1016/j.cell.2015.07.017" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2015/07/30 00:00" ["sortfirstauthor"]=> string(11) "Sullivan LB" ["vernaculartitle"]=> string(0) "" } [25671107]=> array(43) { ["uid"]=> string(8) "25671107" ["pubdate"]=> string(4) "2014" ["epubdate"]=> string(11) "2014 Nov 28" ["source"]=> string(12) "Cancer Metab" ["authors"]=> array(2) { [0]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(10) "Chandel NS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(10) "Chandel NS" ["title"]=> string(49) "Mitochondrial reactive oxygen species and cancer." ["sorttitle"]=> string(48) "mitochondrial reactive oxygen species and cancer" ["volume"]=> string(1) "2" ["issue"]=> string(0) "" ["pages"]=> string(2) "17" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101607582" ["issn"]=> string(0) "" ["essn"]=> string(9) "2049-3002" ["pubtype"]=> array(2) { [0]=> string(15) "Journal Article" [1]=> string(6) "Review" } ["recordstatus"]=> string(6) "PubMed" ["pubstatus"]=> string(3) "258" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "25671107" } [1]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(22) "10.1186/2049-3002-2-17" } [2]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(3) "138" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC4323058" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "25671107" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "25671107" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC4323058;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2014/06/03 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2014/08/27 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2015/02/12 06:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2015/02/12 06:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2015/02/12 06:01" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(125) ["fulljournalname"]=> string(23) "Cancer & metabolism" ["elocationid"]=> string(27) "doi: 10.1186/2049-3002-2-17" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2014/11/28 00:00" ["sortfirstauthor"]=> string(11) "Sullivan LB" ["vernaculartitle"]=> string(0) "" } [25347702]=> array(43) { ["uid"]=> string(8) "25347702" ["pubdate"]=> string(11) "2014 Oct 24" ["epubdate"]=> string(11) "2014 Oct 24" ["source"]=> string(8) "BMC Biol" ["authors"]=> array(3) { [0]=> array(3) { ["name"]=> string(8) "Luengo A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(9) "Heiden MG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(9) "Heiden MG" ["title"]=> string(113) "Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy." ["sorttitle"]=> string(111) "understanding the complex i ty of metformin action limiting mitochondrial respiration to improve cancer therapy" ["volume"]=> string(2) "12" ["issue"]=> string(0) "" ["pages"]=> string(2) "82" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101190720" ["issn"]=> string(0) "" ["essn"]=> string(9) "1741-7007" ["pubtype"]=> array(2) { [0]=> string(7) "Comment" [1]=> string(15) "Journal Article" } ["recordstatus"]=> string(6) "PubMed" ["pubstatus"]=> string(1) "3" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "25347702" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(17) "s12915-014-0082-4" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(25) "10.1186/s12915-014-0082-4" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC4207883" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "25347702" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "25347702" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC4207883;" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2014/10/28 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2014/10/28 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2014/10/28 06:01" } } ["references"]=> array(1) { [0]=> array(4) { ["refsource"]=> string(23) "Cancer Metab. 2014;2:12" ["reftype"]=> string(10) "Comment on" ["pmid"]=> int(25184038) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(21) ["fulljournalname"]=> string(11) "BMC biology" ["elocationid"]=> string(30) "doi: 10.1186/s12915-014-0082-4" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2014/10/24 00:00" ["sortfirstauthor"]=> string(8) "Luengo A" ["vernaculartitle"]=> string(0) "" } [24857658]=> array(43) { ["uid"]=> string(8) "24857658" ["pubdate"]=> string(11) "2014 Jun 12" ["epubdate"]=> string(11) "2014 May 22" ["source"]=> string(8) "Cell Rep" ["authors"]=> array(12) { [0]=> array(3) { ["name"]=> string(9) "Mullen AR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(4) "Hu Z" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(5) "Shi X" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(7) "Jiang L" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(11) "Boroughs LK" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(8) "Kovacs Z" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(9) "Boriack R" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(9) "Rakheja D" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(10) "Linehan WM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(10) "Chandel NS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [11]=> array(3) { ["name"]=> string(15) "DeBerardinis RJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(15) "DeBerardinis RJ" ["title"]=> string(116) "Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects." ["sorttitle"]=> string(115) "oxidation of alpha ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects" ["volume"]=> string(1) "7" ["issue"]=> string(1) "5" ["pages"]=> string(9) "1679-1690" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101573691" ["issn"]=> string(0) "" ["essn"]=> string(9) "2211-1247" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "24857658" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S2211-1247(14)00339-8" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(28) "10.1016/j.celrep.2014.04.037" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC4057960" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(11) "NIHMS591624" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "24857658" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "24857658" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(46) "pmc-id: PMC4057960;manuscript-id: NIHMS591624;" } } ["history"]=> array(6) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2013/10/28 00:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "revised" ["date"]=> string(16) "2014/03/09 00:00" } [2]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2014/04/21 00:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2014/05/27 06:00" } [4]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2014/05/27 06:00" } [5]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2015/08/22 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(90) ["fulljournalname"]=> string(12) "Cell reports" ["elocationid"]=> string(33) "doi: 10.1016/j.celrep.2014.04.037" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2014/06/12 00:00" ["sortfirstauthor"]=> string(9) "Mullen AR" ["vernaculartitle"]=> string(0) "" } [24843020]=> array(43) { ["uid"]=> string(8) "24843020" ["pubdate"]=> string(11) "2014 May 13" ["epubdate"]=> string(11) "2014 May 13" ["source"]=> string(5) "Elife" ["authors"]=> array(11) { [0]=> array(3) { ["name"]=> string(10) "Wheaton WW" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(11) "Weinberg SE" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(11) "Hamanaka RB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(11) "Soberanes S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(6) "Anso E" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(10) "Glasauer A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(8) "Dufour E" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(8) "Mutlu GM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(11) "Budigner GS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(10) "Chandel NS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(10) "Chandel NS" ["title"]=> string(83) "Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis." ["sorttitle"]=> string(82) "metformin inhibits mitochondrial complex i of cancer cells to reduce tumorigenesis" ["volume"]=> string(1) "3" ["issue"]=> string(0) "" ["pages"]=> string(6) "e02242" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101579614" ["issn"]=> string(0) "" ["essn"]=> string(9) "2050-084X" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "3" ["articleids"]=> array(6) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "24843020" } [1]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC4017650" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(19) "10.7554/eLife.02242" } [3]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "24843020" } [4]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "24843020" } [5]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC4017650;" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2014/05/21 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2014/05/21 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2014/05/21 06:01" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(214) ["fulljournalname"]=> string(5) "eLife" ["elocationid"]=> string(24) "doi: 10.7554/eLife.02242" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2014/05/13 00:00" ["sortfirstauthor"]=> string(10) "Wheaton WW" ["vernaculartitle"]=> string(0) "" } [24335489]=> array(43) { ["uid"]=> string(8) "24335489" ["pubdate"]=> string(4) "2014" ["epubdate"]=> string(11) "2013 Dec 13" ["source"]=> string(10) "Cell Cycle" ["authors"]=> array(2) { [0]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(10) "Chandel NS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(10) "Chandel NS" ["title"]=> string(58) "Mitochondrial metabolism in TCA cycle mutant cancer cells." ["sorttitle"]=> string(57) "mitochondrial metabolism in tca cycle mutant cancer cells" ["volume"]=> string(2) "13" ["issue"]=> string(1) "3" ["pages"]=> string(5) "347-8" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101137841" ["issn"]=> string(9) "1538-4101" ["essn"]=> string(9) "1551-4005" ["pubtype"]=> array(2) { [0]=> string(7) "Comment" [1]=> string(9) "Editorial" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "24335489" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(5) "27513" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(16) "10.4161/cc.27513" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC3956527" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "24335489" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "24335489" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC3956527;" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2013/12/17 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2013/12/18 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2015/01/15 06:00" } } ["references"]=> array(1) { [0]=> array(4) { ["refsource"]=> string(34) "Mol Cell. 2013 Jul 25;51(2):236-48" ["reftype"]=> string(10) "Comment on" ["pmid"]=> int(23747014) ["note"]=> string(0) "" } } ["attributes"]=> array(0) { } ["pmcrefcount"]=> int(3) ["fulljournalname"]=> string(29) "Cell cycle (Georgetown, Tex.)" ["elocationid"]=> string(21) "doi: 10.4161/cc.27513" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2014/01/01 00:00" ["sortfirstauthor"]=> string(11) "Sullivan LB" ["vernaculartitle"]=> string(0) "" } [23747014]=> array(43) { ["uid"]=> string(8) "23747014" ["pubdate"]=> string(11) "2013 Jul 25" ["epubdate"]=> string(10) "2013 Jun 6" ["source"]=> string(8) "Mol Cell" ["authors"]=> array(9) { [0]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(17) "Martinez-Garcia E" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(8) "Nguyen H" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(9) "Mullen AR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(8) "Dufour E" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(11) "Sudarshan S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(8) "Licht JD" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(15) "Deberardinis RJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(10) "Chandel NS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(10) "Chandel NS" ["title"]=> string(87) "The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling." ["sorttitle"]=> string(82) "proto oncometabolite fumarate binds glutathione to amplify ros dependent signaling" ["volume"]=> string(2) "51" ["issue"]=> string(1) "2" ["pages"]=> string(6) "236-48" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "9802571" ["issn"]=> string(9) "1097-2765" ["essn"]=> string(9) "1097-4164" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "23747014" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S1097-2765(13)00366-3" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(28) "10.1016/j.molcel.2013.05.003" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC3775267" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(11) "NIHMS511733" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "23747014" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "23747014" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(46) "pmc-id: PMC3775267;manuscript-id: NIHMS511733;" } } ["history"]=> array(6) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2012/09/11 00:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "revised" ["date"]=> string(16) "2013/03/20 00:00" } [2]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2013/05/02 00:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2013/06/11 06:00" } [4]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2013/06/12 06:00" } [5]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2013/11/12 06:00" } } ["references"]=> array(2) { [0]=> array(4) { ["refsource"]=> string(31) "Mol Cell. 2013 Jul 25;51(2):273" ["reftype"]=> string(10) "Erratum in" ["pmid"]=> string(0) "" ["note"]=> string(0) "" } [1]=> array(4) { ["refsource"]=> string(28) "Cell Cycle. 2014;13(3):347-8" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(24335489) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(88) ["fulljournalname"]=> string(14) "Molecular cell" ["elocationid"]=> string(33) "doi: 10.1016/j.molcel.2013.05.003" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2013/07/25 00:00" ["sortfirstauthor"]=> string(11) "Sullivan LB" ["vernaculartitle"]=> string(0) "" } [23020852]=> array(43) { ["uid"]=> string(8) "23020852" ["pubdate"]=> string(11) "2012 Sep 28" ["epubdate"]=> string(0) "" ["source"]=> string(8) "Mol Cell" ["authors"]=> array(3) { [0]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(9) "Santos JH" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(10) "Chandel NS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(10) "Chandel NS" ["title"]=> string(58) "Mitochondria and telomeres: the promiscuous roles of TIN2." ["sorttitle"]=> string(56) "mitochondria and telomeres the promiscuous roles of tin2" ["volume"]=> string(2) "47" ["issue"]=> string(1) "6" ["pages"]=> string(5) "823-4" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "9802571" ["issn"]=> string(9) "1097-2765" ["essn"]=> string(9) "1097-4164" ["pubtype"]=> array(2) { [0]=> string(7) "Comment" [1]=> string(15) "Journal Article" } ["recordstatus"]=> string(6) "PubMed" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(5) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "23020852" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S1097-2765(12)00782-4" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(28) "10.1016/j.molcel.2012.09.006" } [3]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "23020852" } [4]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "23020852" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2012/10/02 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2012/10/02 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2012/10/02 06:01" } } ["references"]=> array(1) { [0]=> array(4) { ["refsource"]=> string(34) "Mol Cell. 2012 Sep 28;47(6):839-50" ["reftype"]=> string(10) "Comment on" ["pmid"]=> int(22885005) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(4) ["fulljournalname"]=> string(14) "Molecular cell" ["elocationid"]=> string(33) "doi: 10.1016/j.molcel.2012.09.006" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2012/09/28 00:00" ["sortfirstauthor"]=> string(11) "Sullivan LB" ["vernaculartitle"]=> string(0) "" } [22101431]=> array(43) { ["uid"]=> string(8) "22101431" ["pubdate"]=> string(11) "2011 Nov 20" ["epubdate"]=> string(11) "2011 Nov 20" ["source"]=> string(6) "Nature" ["authors"]=> array(10) { [0]=> array(3) { ["name"]=> string(9) "Mullen AR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(10) "Wheaton WW" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(6) "Jin ES" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(7) "Chen PH" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(11) "Sullivan LB" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(7) "Cheng T" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(6) "Yang Y" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(10) "Linehan WM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(10) "Chandel NS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(15) "DeBerardinis RJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(15) "DeBerardinis RJ" ["title"]=> string(84) "Reductive carboxylation supports growth in tumour cells with defective mitochondria." ["sorttitle"]=> string(83) "reductive carboxylation supports growth in tumour cells with defective mitochondria" ["volume"]=> string(3) "481" ["issue"]=> string(4) "7381" ["pages"]=> string(5) "385-8" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0410462" ["issn"]=> string(9) "0028-0836" ["essn"]=> string(9) "1476-4687" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "3" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "22101431" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(11) "nature10642" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(19) "10.1038/nature10642" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC3262117" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(11) "NIHMS331574" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "22101431" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "22101431" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(46) "pmc-id: PMC3262117;manuscript-id: NIHMS331574;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2011/06/13 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2011/10/13 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2011/11/22 06:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2011/11/22 06:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2012/03/07 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(399) ["fulljournalname"]=> string(6) "Nature" ["elocationid"]=> string(24) "doi: 10.1038/nature10642" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2011/11/20 00:00" ["sortfirstauthor"]=> string(9) "Mullen AR" ["vernaculartitle"]=> string(0) "" } } }

Publications

The following publications were retrieved from PubMed:

Metabolic Frugality Marks Cancer Cells for Immune Targeting.

Sullivan LB

Cell. 2018 Sep 6; 6(174)1344-1346

Aspartate is an endogenous metabolic limitation for tumour growth.

Sullivan LB, Luengo A, Danai LV, Bush LN, Diehl FF, Hosios AM, Lau AN, Elmiligy S, Malstrom S, Lewis CA, Vander Heiden MG.

Nat Cell Biol. 2018 Jul; 7(20)782-788

Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy.

McLellan CA, Vincent BM, Solis NV, Lancaster AK, Sullivan LB, Hartland CL, Youngsaye W, Filler SG, Whitesell L, Lindquist S.

Nat Chem Biol. 2018 Feb; 2(14)135-141

Extracellular vesicles: Taking metabolism on the road.

Sullivan LB

Nat Chem Biol. 2017 Aug 18; 9(13)924-925

Altered metabolite levels in cancer: implications for tumour biology and cancer therapy.

Sullivan LB, Gui DY, Vander Heiden MG.

Nat Rev Cancer. 2016 Nov; 11(16)680-693

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Lab Information

Location: Fred Hutchinson Cancer Research Center
Building: Hutchinson
Room: C3-187