faculty
Alison Feder
affeder@uw.edu
Assistant Professor
University of Washington
Cancer Biology
Computational Biology
Genetics, Genomics & Evolution
Evolutionary dynamics in viruses and cancer
Faculty Contact Information
Box: 355065
Research Summary
Our goal is to understand the dynamics of rapidly-evolving populations, especially viruses evolving within their hosts and solid tumors progressing to malignancy. In particular, we are characterizing how spatial organization shapes these evolutionary outcomes, and developing approaches to leverage spatial data to better understand evolutionary histories.
DEI Statement
I will create a supportive environment that aims to allow all of its members (future and current) to thrive. At its core, this means we must respect all members of our community. We will talk openly and regularly about how we can make science a more inclusive endeavor. We will not tolerate bullying, and we will confront microaggressions.
Training Summary
DEI Training (Lavender Rights Project, 6 hours)
Entering Mentoring Workshop (CIMER, 8 hours)
Race, Bias and Dissonance Training (4 hours)
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Publications
The following publications were retrieved from PubMed:
Feder AF, Harper KN, Brumme CJ, Pennings PS.
Elife. 2021 Sep 2; (10)
The clarifying role of time series data in the population genetics of HIV.
Feder AF, Pennings PS, Petrov DA.
PLoS Genet. 2021 Jan; 1(17)e1009050
Evolutionary Dynamics in Structured Populations Under Strong Population Genetic Forces.
Feder AF, Pennings PS, Hermisson J, Petrov DA.
G3 (Bethesda). 2019 Oct 7; 10(9)3395-3407
The Relationship Between Haplotype-Based F(ST) and Haplotype Length.
Mehta RS, Feder AF, Boca SM, Rosenberg NA.
Genetics. 2019 Sep; 1(213)281-295
Theys K, Feder AF, Gelbart M, Hartl M, Stern A, Pennings PS.
PLoS Genet. 2018 Dec; 12(14)e1007855
Theys K, Feder AF, Gelbart M, Hartl M, Stern A, Pennings PS.
PLoS Genet. 2018 Jun; 6(14)e1007420
Feder AF, Kline C, Polacino P, Cottrell M, Kashuba ADM, Keele BF, Hu SL, Petrov DA, Pennings PS, Ambrose Z.
PLoS Pathog. 2017 May; 5(13)e1006358
Feder AF, Rhee SY, Holmes SP, Shafer RW, Petrov DA, Pennings PS.
Elife. 2017 Jan 19; (6)
More effective drugs lead to harder selective sweeps in the evolution of drug resistance in HIV-1.
Feder AF, Rhee SY, Holmes SP, Shafer RW, Petrov DA, Pennings PS.
Elife. 2016 Feb 15; (5)
Wilson BA, Garud NR, Feder AF, Assaf ZJ, Pennings PS.
Mol Ecol. 2016 Jan; 1(25)42-66
Identifying signatures of selection in genetic time series.
Feder AF, Kryazhimskiy S, Plotkin JB.
Genetics. 2014 Feb; 2(196)509-22
LDx: estimation of linkage disequilibrium from high-throughput pooled resequencing data.
Feder AF, Petrov DA, Bergland AO.
PLoS One. 2012; 11(7)e48588
Lohmueller KE, Albrechtsen A, Li Y, Kim SY, Korneliussen T, Vinckenbosch N, Tian G, Huerta-Sanchez E, Feder AF, Grarup N, Jørgensen T, Jiang T, Witte DR, Sandbæk A, Hellmann I, Lauritzen T, Hansen T, Pedersen O, Wang J, Nielsen R.
PLoS Genet. 2011 Oct; 10(7)e1002326
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