Rong Tian
rongtian@uw.eduUniversity of Washington,
Cell Signaling & Cell/Environment Interactions
Developmental Biology, Stem Cells & Aging
Mitochondrial and Metabolic mechanisms of human diseases
Faculty Contact Information
Lab Information
Accepting Students For:
Publications
Heart specific knockout of Ndufs4 ameliorates ischemia reperfusion injury.
Zhang H, Gong G, Wang P, Zhang Z, Kolwicz SC, Rabinovitch PS, Tian R, Wang W.
Journal of molecular and cellular cardiology. 2018; 123:38-45. NIHMSID: NIHMS990623
- PMID:
- 30165037
- PMCID:
- PMC6192835
Mitochondrial dysfunction in pathophysiology of heart failure.
Zhou B, Tian R.
The Journal of clinical investigation. 2018; 128(9):3716-3726.
- PMID:
- 30124471
- PMCID:
- PMC6118589
Glucose promotes cell growth by suppressing branched-chain amino acid degradation.
Shao D, Villet O, Zhang Z, Choi SW, Yan J, Ritterhoff J, Gu H, Djukovic D, Christodoulou D, Kolwicz SC Jr, Raftery D, Tian R.
Nature communications. 2018; 9(1):2935.
- PMID:
- 30050148
- PMCID:
- PMC6062555
NAD(H) in Mitochondrial Energy Transduction: Implications for Health and Disease
Walker MA, Tian R.
Current Opinion in Physiology. 2018 June; 3(Mitochondrial Biology):101-109.
Raising NAD in Heart Failure: Time to Translate?
Walker MA, Tian R.
Circulation. 2018; 137(21):2274-2277. NIHMSID: NIHMS954031
- PMID:
- 29784680
- PMCID:
- PMC5967641
The Role of Diacylglycerol Acyltransferase (DGAT) 1 and 2 in Cardiac Metabolism and Function.
Roe ND, Handzlik MK, Li T, Tian R.
Scientific reports. 2018; 8(1):4983.
- PMID:
- 29563512
- PMCID:
- PMC5862879
Chavez JD, Lee CF, Caudal A, Keller A, Tian R, Bruce JE.
Cell systems. 2018; 6(1):136-141.e5. NIHMSID: NIHMS922763
- PMID:
- 29199018
- PMCID:
- PMC5799023
Failed Power Plant Turns Into Mass Murder: New Insight on Mitochondrial Cardiomyopathy.
Lee CF, Cao Y, Tian R.
Circulation research. 2018; 122(1):11-13. NIHMSID: NIHMS923169
- PMID:
- 29301837
- PMCID:
- PMC5757239
Airhart SE, Shireman LM, Risler LJ, Anderson GD, Nagana Gowda GA, Raftery D, Tian R, Shen DD, O'Brien KD.
PloS one. 2017; 12(12):e0186459.
- PMID:
- 29211728
- PMCID:
- PMC5718430
Cao Y, Bojjireddy N, Kim M, Li T, Zhai P, Nagarajan N, Sadoshima J, Palmiter RD, Tian R.
Circulation research. 2017; 121(10):1182-1191. NIHMSID: NIHMS901807
- PMID:
- 28835357
- PMCID:
- PMC5659937
Research Summary
The Tian Laboratory focuses on the roles of cell metabolism and mitochondrial function in the pathogenesis of human diseases. Our research combines the high resolution NMR techniques and metabolomics with the ability to target molecular regulatory mechanisms via genetic manipulation in animal models. Current research topics include:
Mitochondrial mechanisms in stress response;
Metabolic reprogramming during the development and disease;
Regulation of pathological cardiac hypertrophy by substrate metabolism.