faculty

Rong Tian

rongtian@uw.edu
Professor

University of Washington

Biochemistry

Cell Signaling & Cell/Environment Interactions

Developmental Biology, Stem Cells & Aging

Mitochondrial and Metabolic mechanisms of human diseases

Faculty Contact Information

Building: SLU North Building Room: N130 Box: Box 358057 Phone: 206-543-8982 Alt Phone: 206-616-5672 https://sites.uw.edu/mmcslu/faculty/rong_tian-md-phd/

Research Summary

The Tian Laboratory focuses on the roles of cell metabolism and mitochondrial function in the pathogenesis of human diseases. Our research combines the high resolution NMR techniques and metabolomics with the ability to target molecular regulatory mechanisms via genetic manipulation in animal models. Current research topics include:
Mitochondrial mechanisms in stress response;
Metabolic reprogramming during the development and disease;
Mitochondrial protein interactome
Targeting NAD metabolism for therapy

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Publications

The following publications were retrieved from PubMed:

Targeting NAD<sup>+</sup> Metabolism as Interventions for Mitochondrial Disease.

Lee CF, Caudal A, Abell L, Nagana Gowda GA, Tian R.

Sci Rep. 2019 Feb 28; 1(9)3073

Heart specific knockout of Ndufs4 ameliorates ischemia reperfusion injury.

Zhang H, Gong G, Wang P, Zhang Z, Kolwicz SC, Rabinovitch PS, Tian R, Wang W.

J Mol Cell Cardiol. 2018 Oct; (123)38-45

Glucose promotes cell growth by suppressing branched-chain amino acid degradation.

Shao D, Villet O, Zhang Z, Choi SW, Yan J, Ritterhoff J, Gu H, Djukovic D, Christodoulou D, Kolwicz SC Jr, Raftery D, Tian R.

Nat Commun. 2018 Jul 26; 1(9)2935

Raising NAD in Heart Failure: Time to Translate?

Walker MA, Tian R.

Circulation. 2018 May 22; 21(137)2274-2277

The Role of Diacylglycerol Acyltransferase (DGAT) 1 and 2 in Cardiac Metabolism and Function.

Roe ND, Handzlik MK, Li T, Tian R.

Sci Rep. 2018 Mar 21; 1(8)4983

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Lab Information

Location: UW SLU campus
Building: North Building
Room: N130
Box: Box 358057
Phone: 206-543-8982
https://sites.uw.edu/mmcslu/laboratories/research-laboratories-tian-lab-2-2-2/