student

Alexandre Germanos

alexg22@uw.edu

Fred Hutch

Human Biology

Cancer Biology

Computational Biology

Entry Quarter: Autumn 2017
Defense date: 12/13/2019
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Publications

The following publications were retrieved from PubMed:

Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress.

Cai EY, Kufeld MN, Schuster S, Arora S, Larkin M, Germanos AA, Hsieh AC, Beronja S.

Cell Stem Cell. 2020 Aug 6; 2(27)270-283.e7

The androgen receptor regulates a druggable translational regulon in advanced prostate cancer.

Liu Y, Horn JL, Banda K, Goodman AZ, Lim Y, Jana S, Arora S, Germanos AA, Wen L, Hardin WR, Yang YC, Coleman IM, Tharakan RG, Cai EY, Uo T, Pillai SPS, Corey E, Morrissey C, Chen Y, Carver BS, Plymate SR, Beronja S, Nelson PS, Hsieh AC.

Sci Transl Med. 2019 Jul 31; 503(11)

Glucocerebrosidase Deficiency in Drosophila Results in α-Synuclein-Independent Protein Aggregation and Neurodegeneration.

Davis MY, Trinh K, Thomas RE, Yu S, Germanos AA, Whitley BN, Sardi SP, Montine TJ, Pallanck LJ.

PLoS Genet. 2016 Mar; 3(12)e1005944

Striking similarities in genetic aberrations between a rectal tumor and its lung recurrence.

Rahma OE, Burotto M, Do Canto LM, Germanos AA, Haddad BR, Marshall JL.

World J Gastrointest Oncol. 2013 Nov 15; 11(5)198-203



Publications Link

Research Summary

My projects are focused on understanding the genetics and genomics of prostate cancer. I am investigating the function of a cis-regulatory element in mRNA transcripts involved in prostate cancer proliferation, and using computational tools to characterize the cellular makeup of the prostate and the effects of cancer on this environment.

Lab Information

Advisor: Andrew Hsieh