student

Ricky Padilla-Del Valle

rickyyyy@uw.edu

Pacific Northwest Research Institute

Genome Sciences

Gene Expression, Cell Cycle & Chromosome Biology

Entry Quarter: Summer 2018
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Publications

The following publications were retrieved from PubMed:

A vasculature-centric approach to developing novel treatment options for glioblastoma.

Wirsching HG, Roth P, Weller M.

Expert Opin Ther Targets. 2021 Jan 22;

Why do knees after total knee arthroplasty fail in different parts of the world?

Mathis DT, Hirschmann MT.

J Orthop. 2021 Jan-Feb; (23)52-59

COVID-19 pathways for brain and heart injury in comorbidity patients: A role of medical imaging and artificial intelligence-based COVID severity classification: A review.

Suri JS, Puvvula A, Biswas M, Majhail M, Saba L, Faa G, Singh IM, Oberleitner R, Turk M, Chadha PS, Johri AM, Sanches JM, Khanna NN, Viskovic K, Mavrogeni S, Laird JR, Pareek G, Miner M, Sobel DW, Balestrieri A, Sfikakis PP, Tsoulfas G, Protogerou A, Misra DP, Agarwal V, Kitas GD, Ahluwalia P, Kolluri R, Teji J, Maini MA, Agbakoba A, Dhanjil SK, Sockalingam M, Saxena A, Nicolaides A, Sharma A, Rathore V, Ajuluchukwu JNA, Fatemi M, Alizad A, Viswanathan V, Krishnan PR, Naidu S.

Comput Biol Med. 2020 Sep; (124)103960

Daratumumab subcutaneous formulation for the treatment of multiple myeloma.

Paul B, Hamadeh I, Atrash S, Bhutani M, Voorhees P, Usmani SZ.

Expert Opin Biol Ther. 2020 Nov; 11(20)1253-1259



Publications Link

Research Summary

While mobile genetic elements inflate and sculpture the host genome, intrinsic genomic defenses arise in response to battle change and reestablish order. This co-evolutionary interplay allows pathogens like the retrotransposon Long Interspersed Element 1 (LINE-1) generate biologically expensive changes. As part of the McLaughlin Lab, I use evolutionary-guided methods driven by phylogenetics and experimental evolution to functionally access and describe the nature and dynamics of LINE-1 diversification and its consequences in shaping human genomes.

Lab Information

Advisor: Rick McLaughlin

Rotation Labs