Ricky Padilla-Del Valle

Diversity Committee

Gene Expression, Cell Cycle & Chromosome Biology

Genetics, Genomics & Evolution

Entry Quarter: Summer 2018

Research Summary

While mobile genetic elements inflate and sculpture the host genome, intrinsic genomic defenses arise in response to battle change and reestablish order. This co-evolutionary interplay allows pathogens like the retrotransposon Long Interspersed Element 1 (LINE-1) to generate biologically expensive changes that translate into mutagenic events, and consequently disease. As part of the McLaughlin Lab, I use evolutionary-guided methods driven by phylogenetics and experimental evolution to functionally access and describe the nature and dynamics of LINE-1 diversification and its consequences in individual human genomes.

Lab Information

Advisor: Rick McLaughlin