Ricky Padilla-Del Vallerickyyyy@uw.edu
Pacific Northwest Research Institute,
Gene Expression, Cell Cycle & Chromosome Biology
The following publications were retrieved from PubMed:
Wirsching HG, Roth P, Weller M.
Expert Opin Ther Targets. 2021 Jan 22;
Mathis DT, Hirschmann MT.
J Orthop. 2021 Jan-Feb; (23)52-59
Rendic S, Guengerich FP.
Curr Drug Metab. 2020; 14(21)1127-1135
Suri JS, Puvvula A, Biswas M, Majhail M, Saba L, Faa G, Singh IM, Oberleitner R, Turk M, Chadha PS, Johri AM, Sanches JM, Khanna NN, Viskovic K, Mavrogeni S, Laird JR, Pareek G, Miner M, Sobel DW, Balestrieri A, Sfikakis PP, Tsoulfas G, Protogerou A, Misra DP, Agarwal V, Kitas GD, Ahluwalia P, Kolluri R, Teji J, Maini MA, Agbakoba A, Dhanjil SK, Sockalingam M, Saxena A, Nicolaides A, Sharma A, Rathore V, Ajuluchukwu JNA, Fatemi M, Alizad A, Viswanathan V, Krishnan PR, Naidu S.
Comput Biol Med. 2020 Sep; (124)103960
Paul B, Hamadeh I, Atrash S, Bhutani M, Voorhees P, Usmani SZ.
Expert Opin Biol Ther. 2020 Nov; 11(20)1253-1259
Ebrahimpour-Koujan S, Saneei P, Larijani B, Esmaillzadeh A.
J Hum Nutr Diet. 2020 Jul 19;
While mobile genetic elements inflate and sculpture the host genome, intrinsic genomic defenses arise in response to battle change and reestablish order. This co-evolutionary interplay allows pathogens like the retrotransposon Long Interspersed Element 1 (LINE-1) generate biologically expensive changes. As part of the McLaughlin Lab, I use evolutionary-guided methods driven by phylogenetics and experimental evolution to functionally access and describe the nature and dynamics of LINE-1 diversification and its consequences in shaping human genomes.