student

Derrick R. Hicks

drhicks1@uw.edu

University of Washington

Biochemistry

Entry Quarter: Summer 2015
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Publications

The following publications were retrieved from PubMed:

Massively parallel de novo protein design for targeted therapeutics.

Chevalier A, Silva DA, Rocklin GJ, Hicks DR, Vergara R, Murapa P, Bernard SM, Zhang L, Lam KH, Yao G, Bahl CD, Miyashita SI, Goreshnik I, Fuller JT, Koday MT, Jenkins CM, Colvin T, Carter L, Bohn A, Bryan CM, Fernández-Velasco DA, Stewart L, Dong M, Huang X, Jin R, Wilson IA, Fuller DH, Baker D.

Nature. 2017 Oct 5; 7674(550)74-79

Human CTP synthase filament structure reveals the active enzyme conformation.

Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM.

Nat Struct Mol Biol. 2017 Jun; 6(24)507-514

Supplementation with Abscisic Acid Reduces Malaria Disease Severity and Parasite Transmission.

Glennon EK, Adams LG, Hicks DR, Dehesh K, Luckhart S.

Am J Trop Med Hyg. 2016 Jun 1; 6(94)1266-75

The plastidial retrograde signal methyl erythritol cyclopyrophosphate is a regulator of salicylic acid and jasmonic acid crosstalk.

Lemos M, Xiao Y, Bjornson M, Wang JZ, Hicks D, Souza Ad, Wang CQ, Yang P, Ma S, Dinesh-Kumar S, Dehesh K.

J Exp Bot. 2016 Mar; 5(67)1557-66

A key general stress response motif is regulated non-uniformly by CAMTA transcription factors.

Benn G, Wang CQ, Hicks DR, Stein J, Guthrie C, Dehesh K.

Plant J. 2014 Oct; 1(80)82-92



Publications Link

Research Summary

My research focus is on the design of protein interfaces, both protein-protein interfaces and protein-small molecule interfaces. My long term goal is the design completely de novo chemically induced dimers which could be used as basic science research tools or in the control of engineered cell biologics.

Lab Information

Advisor: David Baker