University of Washington,
Microbiology, Infection & Immunity
Microbiome and mucosal dysfunction in HIV transmission and pathogenesis
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The complex interactions between the epithelial barrier, the microbiome, mucus and immune cells are critical for protection from disease. The focus of my lab is to understand mechanisms underlying mucosal dysfunction, microbiome dysbiosis and altered immunity in mucosal tissues (mainly gastrointestinal and female reproductive tracts), and how these defects contribute to HIV transmission and pathogenesis. Our ultimate goal is to improve prevention and treatment strategies for HIV infection.