Cochlear culture

How to see what we hear
Connections explored

Probing synaptic transmission in culture

Neuroscience

Neuroscience research in Seattle MCB seeks to understand nervous system development, brain function, and neurological diseases at the cellular and molecular level through a combination of molecular, genetic, electrophysiological, computational, and behavioral approaches.

Model Curricula

Autumn

CONJ 531
Signaling Mechanisms in Excitable Cells

NEURO 504, PBIO 504
Biophysics of Nerve, Muscle, and Synapse

MCB 522
The Developmental Basis of Human Disease

winter

CONJ 544
Protein Structure, Modification and Regulation

spring

NEURO 548, PBIO 548
Molecular Mechanisms of Synaptic Plasticity

NEURO 557, PBIO 557
Ion Channel Gating

Connections matter

Seattle is a major hub for studies in Neuroscience.

UW Computational Neuroscience

Center for Sensorimotor Neural Engineering

Bloedel Center for Speech and Hearing

Seattle Childrens’ Neuroscience Institute

UW Neurosciences Institute

Allen Institute for Brain Science

Faculty Area Directors: Olivia Bermingham-McDonogh, Jihong Bai

Student Area Directors: Marcella Cline

Area Of interest Faculty

Featured Research

Area Directors

Faculty Area Directors: Olivia Bermingham-McDonogh, Jihong Bai

Student Area Directors: Marcella Cline, Alex Neitz, Carrie Stine

Lab Openings

Rajan Lab:
All Quarters, Permanent Position

Fat's impact on cognition & immunity

Singhvi Lab:
All Quarters, Permanent Position

glia, neuron, cell signaling, sensory systems

Bajjalieh Lab:
Autumn, Spring, Winter, Permanent Position

cell signaling, neuroscience, lipid signaling, synapse

Barria Lab:
Spring, Summer, Winter

Glutamatergic receptors, synaptic transmission, synaptic plasticity, Wnt signaling

Grill Lab:
Permanent Position

proteomics, genetics, neuroscience

Furlong Lab:
Spring

Crowder Lab:
All Quarters, Permanent Position

Hypoxia, genetic screens, C. elegans, drug screens, ischemia, stroke, infarction, cell death, protein misfolding, protein aggregation, mitochondria

Moens Lab:
All Quarters, Permanent Position

zebrafish, genetics, developmental biology, neural development, motor neuron, planar cell polarity, neuroepithelial morphogenesis, neuronal migration, axon guidance.

Daggett Lab:
All Quarters, Permanent Position

computational, protein dynamics, disease, amyloid, protein design, functional amyloid

Dhaka Lab:
Autumn, Spring, Winter

Raible Lab:
All Quarters, Permanent Position

zebrafish, lateral line, hair cell, hearing, deafness, genetics, crispr

Veesler Lab:
All Quarters, Permanent Position

Cryo-electron microscopy, viruses, viral fusion proteins, bacterial secretion systems, ion channels,vaccine design, structure-based drug design

Bai Lab:
All Quarters, Permanent Position

Brain, neuron, synapse, neurotransmitter, endocytosis, exocytosis, C. elegans,

Young Lab:
All Quarters

stem cells, neurons, alzheimer's disease

Parrish Lab:
Autumn, Spring, Winter, Permanent Position

Somatosensory neuron development in Drosophila

Kraemer Lab:
All Quarters, Permanent Position

Amyotrophic lateral sclerosis, Alzheiemer's disease, Frontotemporal Lobar Degeneration Neurodegeneration, tau, TDP-43, protein aggregation, proteostasis

Ailion Lab:
All Quarters, Permanent Position

C. elegans, neurobiology, genetics, speciation, neuromodulation, G protein, insulin, diabetes, signal transduction, hybrid incompatibility, mitochondria, selfish genes

Bruchas Lab:
All Quarters, Permanent Position

Neuronal Signaling, GPCRs, Optogenetics, Neural Circuits, Computation, Neuropeptides, RNA, Cellular Imaging, Physiology, Arrestin, Kinases, G-proteins,

King Lab:
Permanent Position

human genetics, cancer genetics, gene discovery, genomics

McKnight Lab:
All Quarters, Permanent Position

PKA, cAMP, obesity, hypothalamus, leptin, gene expression, memory, learning

Davis Lab:
All Quarters, Permanent Position

GBA, protein aggregation, Parkinson's disease, neurodegeneration

Neumaier Lab:
Spring, Summer, Winter, Permanent Position

serotonin, stress, addiction

Liachko Lab:
All Quarters, Permanent Position

Neurodegeneration, Amyotrophic Lateral Sclerosis (ALS), Alzheimer's disease, C. elegans, primary neurons

Bermingham-McDonogh Lab:
Autumn, Spring, Winter, Permanent Position

Hair cells, inner ear, neurogenesis, regeneration, stem cells, cochlea, vestibular, auditory, ATAC -Seq, Single cell RNA-Se

Pallanck Lab:
All Quarters, Permanent Position

Palmiter Lab:
Autumn, Spring, Winter, Permanent Position

agouti-related protein,calcitonin gene-related protein,feeding behavior,drinking,salt appetite,anorexia,reproduction,temperature regulation

Valdmanis Lab:
All Quarters, Permanent Position

Gene therapy, MicroRNAs, noncoding RNAs, neurogenetics, Amyotrophic Lateral Sclerosis, Alzheimer's disease

Phillips Lab:
All Quarters, Permanent Position

dopamine, nucleus accumbens, striatum, drug addiction, decision making, stress, depression

Promislow Lab:
Spring, Summer, Winter, Permanent Position

senescence, aging, sexual selection, mating, cost of reproduction, Drosophila, metabolomics, quantitative genetics, theory, systems biology, dogs

Rasmussen Lab:
All Quarters, Permanent Position

zebrafish, development, regeneration, organogenesis, neurodegeneration, skin

Gordon Lab:
All Quarters, Permanent Position

Membrane Biophysics, Ion Channels, Protein Dynamics and Energetics

Ferguson Lab:
All Quarters, Permanent Position

addiction, rat, circuits, heroin, cocaine, reward

Yadav Lab:
All Quarters, Permanent Position

Neurodevelopmental Disorders, Kinase Signaling, Autism

Reh Lab:
Autumn, Spring, Winter, Permanent Position

retina, regeneration, stem cells, reprogramming, ESC, brain, transcription, epigenetics, chromatin

Tuthill Lab:
All Quarters, Permanent Position

sensorimotor, mechanosensory, proprioception, touch, computational neuroscience, 2-photon, electrophysiology, drosophila, ventral nerve cord, neural circuits, whole-cell patch-clamp, walking