Jessica Hamerman


Benaroya Research Institute, 

Microbiology, Infection & Immunity

Regulation of macrophage development, function, and inflammatory responses

Faculty Contact Information

Building: Benaroya Research Institute Phone: 206-287-1077 http://immunology.washington.edu/jessica-hamerman-phd

Lab Information

Location: Benaroya Research Institute

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter


The following publications were retrieved from PubMed:

B cell adaptor for PI3-kinase (BCAP) modulates CD8<sup>+</sup> effector and memory T cell differentiation.

Singh MD, Ni M, Sullivan JM, Hamerman JA, Campbell DJ.

J Exp Med. 2018 Sep 3; 9(215)2429-2443

A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome.

Kanter JE, Kramer F, Barnhart S, Duggan JM, Shimizu-Albergine M, Kothari V, Chait A, Bouman SD, Hamerman JA, Hansen BF, Olsen GS, Bornfeldt KE.

Diabetes. 2018 May; 5(67)946-959

cGAS-mediated control of blood-stage malaria promotes Plasmodium-specific germinal center responses.

Hahn WO, Butler NS, Lindner SE, Akilesh HM, Sather DN, Kappe SH, Hamerman JA, Gale M Jr, Liles WC, Pepper M.

JCI Insight. 2018 Jan 25; 2(3)

BCAP inhibits proliferation and differentiation of myeloid progenitors in the steady state and during demand situations.

Duggan JM, Buechler MB, Olson RM, Hohl TM, Hamerman JA.

Blood. 2017 Mar 16; 11(129)1503-1513

Research Summary

Research in the Hamerman Lab is focused on understanding the process of inflammation and how it is regulated. We study macrophages, key inducers of inflammation, and related cells of the myeloid lineage. Our research encompasses regulation of macrophage inflammatory output via pattern recognition receptor signaling, and myeloid cell trafficking, development and homeostasis during health and disease. Our goal is to understand how myeloid cells respond during infection and inflammation, and how this promotes clearance of pathogens and susceptibility to inflammatory and autoimmune disease.