David Fredricks


Fred Hutch, 

Microbiology, Infection & Immunity

The human microbiome

Faculty Contact Information

Lab Information

Location: Fred Hutch Building: Eastlake Box: E4-100 http://research.fhcrc.org/fredricks/en.html

Accepting Students For:

Rotation, Spring
Rotation, Winter


The following publications were retrieved from PubMed:

Primary Syphilis in the Male Urethra - A Case Report.

Chambers LC, Srinivasan S, Lukehart SA, Ocbamichael N, Morgan JL, Lowens MS, Fredricks DN, Golden MR, Manhart LE.

Clin Infect Dis. 2018 Sep 10;

Cross-sectional study of urethral exposures at last sexual episode associated with non-gonococcal urethritis among STD clinic patients.

Chambers LC, Morgan JL, Lowens MS, Robinson TS, Romano SS, Leipertz GL, Hughes JP, Golden MR, Khosropour CM, Fredricks DN, Manhart LE.

Sex Transm Infect. 2018 Sep 4;

Antibiotic Exposure Prior to Respiratory Viral Infection Is Associated with Progression to Lower Respiratory Tract Disease in Allogeneic Hematopoietic Cell Transplant Recipients.

Ogimi C, Krantz EM, Golob JL, Waghmare A, Liu C, Leisenring WM, Woodard CR, Marquis S, Kuypers JM, Jerome KR, Pergam SA, Fredricks DN, Sorror ML, Englund JA, Boeckh M.

Biol Blood Marrow Transplant. 2018 May 16;

Parallel detection of lactobacillus and bacterial vaginosis-associated bacterial DNA in the chorioamnion and vagina of pregnant women at term.

Lannon SMR, Adams Waldorf KM, Fiedler T, Kapur RP, Agnew K, Rajagopal L, Gravett MG, Fredricks DN.

J Matern Fetal Neonatal Med. 2018 Mar 12; 1-9

Evaluation of the association between the concentrations of key vaginal bacteria and the increased risk of HIV acquisition in African women from five cohorts: a nested case-control study.

McClelland RS, Lingappa JR, Srinivasan S, Kinuthia J, John-Stewart GC, Jaoko W, Richardson BA, Yuhas K, Fiedler TL, Mandaliya KN, Munch MM, Mugo NR, Cohen CR, Baeten JM, Celum C, Overbaugh J, Fredricks DN.

Lancet Infect Dis. 2018 May; 5(18)554-564

Research Summary

We study human associated microbial communities, including their composition, structure, dynamics and function. Our goal is to advance our understanding of how microbial populations in humans influence health and susceptibility to disease. Ongoing projects in the lab focus on the gut microbiome in patients with cancer, and the how the genital tract microbiota influences HIV infection and other sexually transmitted infections.