faculty

Judit Villen

jvillen@uw.edu

University of Washington, 

Cancer Biology

Cell Signaling & Cell/Environment Interactions

Cell signaling and Proteomics

Faculty Contact Information

Building: Foege Room: S133C Box: 355065 Phone: 206-685-1490

Lab Information

Location: University of Washington Building: Foege Room: S133A Box: 355065 Phone: 206-543-1880 http://villenlab.gs.washington.edu/

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Publications

The following publications were retrieved from PubMed:

TORC1 and TORC2 converge to regulate the SAGA co-activator in response to nutrient availability.

Laboucarié T, Detilleux D, Rodriguez-Mias RA, Faux C, Romeo Y, Franz-Wachtel M, Krug K, Maček B, Villén J, Petersen J, Helmlinger D.

EMBO Rep. 2017 Dec; 12(18)2197-2218

The phosphatidic acid-binding, polybasic domain is responsible for the differences in the phosphoregulation of lipins 1 and 3.

Boroda S, Takkellapati S, Lawrence RT, Entwisle SW, Pearson JM, Granade ME, Mullins GR, Eaton JM, Villén J, Harris TE.

J Biol Chem. 2017 Dec 15; 50(292)20481-20493

Determinants and Regulation of Protein Turnover in Yeast.

Martin-Perez M, Villén J.

Cell Syst. 2017 Sep 27; 3(5)283-294.e5

An atlas of human kinase regulation.

Ochoa D, Jonikas M, Lawrence RT, El Debs B, Selkrig J, Typas A, Villén J, Santos SD, Beltrao P.

Mol Syst Biol. 2016 Dec 1; 12(12)888

Evolution of protein phosphorylation across 18 fungal species.

Studer RA, Rodriguez-Mias RA, Haas KM, Hsu JI, Viéitez C, Solé C, Swaney DL, Stanford LB, Liachko I, Böttcher R, Dunham MJ, de Nadal E, Posas F, Beltrao P, Villén J.

Science. 2016 Oct 14; 6309(354)229-232

Research Summary

The Villen lab is interested in the organization principles of signaling. We develop and apply proteomic technologies that provide a systems-level view of signaling to reveal signaling components, their connections, and their functional regulation. Our long-term goal is to understand the wiring diagram of a cell at such resolution that we can predict and control cellular output, encompassing molecules, shapes, and functions.