University of Washington,
Cell Signaling & Cell/Environment Interactions
Gene Expression, Cell Cycle & Chromosome Biology
Regulation of nuclear functions by ubiquitin and ubiquitin-like modifications
Faculty Contact Information
Accepting Students For:
The Gardner lab has a broad scope that focuses on how ubiquitin and ubiquitin-like protein modifiers regulate protein function in the nucleus. Main projects in the Gardner lab converge on elucidating the mechanisms of ubiquitin-mediated misfolded protein degradation in nuclear protein quality control, understanding the functions of ubiquitination in regulating ribosome biogenesis at the level of ribosomal rDNA transcription and ribosome assembly, and uncovering novel roles of protein sumoylation in response to cellular stress.
We welcome new thoughts and new ideas! Come join us!!