faculty

John Scott

scottjdw@uw.edu

University of Washington, 

Cell Signaling & Cell/Environment Interactions

Signal transduction events that are controlled by anchoring proteins

Faculty Contact Information

Building: Health Sciences Building Room: K-336B Box: 357750 http://faculty.washington.edu/scottjdw/index.html

Lab Information

Location: University of Washington Building: Health Sciences Builcing Room: K-316 http://faculty.washington.edu/scottjdw/index.html

Accepting Students For:

Rotation, Spring
Rotation, Winter

Research Summary

His research program focuses on defining the intracellular communication networks that promote specificity in signal transduction events. Dr. Scott’s lab has identified a family of A-kinase–anchoring proteins (AKAPs) that target the cAMP-dependent protein kinase (PKA) and other signaling enzymes to specific subcellular sites. AKAPs influence the regulation of physiological processes by bringing enzymes close to their appropriate effectors and substrates at precisely the right moment. Dr. Scott and his lab have made significant progress on establishing the AKAP model, the functional consequence