John Scott


University of Washington, 

Cell Signaling & Cell/Environment Interactions

Signal transduction events that are controlled by anchoring proteins

Faculty Contact Information

Building: Health Sciences Building Room: K-336B Box: 357750 http://faculty.washington.edu/scottjdw/index.html

Lab Information

Location: University of Washington Building: Health Sciences Builcing Room: K-316 http://faculty.washington.edu/scottjdw/index.html

Accepting Students For:

Rotation, Spring
Rotation, Winter


The following publications were retrieved from PubMed:

Hepatitis C continuum of care and utilization of healthcare and harm reduction services among persons who inject drugs in Seattle.

Tsui JI, Miller CM, Scott JD, Corcorran MA, Dombrowski JC, Glick SN.

Drug Alcohol Depend. 2018 Dec 26; (195)114-120

Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins.

Smith FD, Omar MH, Nygren PJ, Soughayer J, Hoshi N, Lau HT, Snyder CG, Branon TC, Ghosh D, Langeberg LK, Ting AY, Santana LF, Ong SE, Navedo MF, Scott JD.

Proc Natl Acad Sci U S A. 2018 Dec 4; 49(115)E11465-E11474

Project ECHO: telementoring to educate and support prescribing of HIV pre-exposure prophylaxis by community medical providers.

Wood BR, Mann MS, Martinez-Paz N, Unruh KT, Annese M, Spach DH, Scott JD, Stekler JD.

Sex Health. 2018 Nov; 6(15)601-605

Protein kinase A activation: Something new under the sun?

Smith FD, Scott JD.

J Cell Biol. 2018 Jun 4; 6(217)1895-1897

Research Summary

His research program focuses on defining the intracellular communication networks that promote specificity in signal transduction events. Dr. Scott’s lab has identified a family of A-kinase–anchoring proteins (AKAPs) that target the cAMP-dependent protein kinase (PKA) and other signaling enzymes to specific subcellular sites. AKAPs influence the regulation of physiological processes by bringing enzymes close to their appropriate effectors and substrates at precisely the right moment. Dr. Scott and his lab have made significant progress on establishing the AKAP model, the functional consequence