faculty
John Scott
scottjdw@uw.eduUniversity of Washington,
Cell Signaling & Cell/Environment Interactions
Signal transduction events that are controlled by anchoring proteins
Faculty Contact Information
Building: Health Sciences Building
Room: K-336B
Box: 357750
http://faculty.washington.edu/scottjdw/index.html
Lab Information
Location: University of Washington
Building: Health Sciences Builcing
Room: K-316
http://faculty.washington.edu/scottjdw/index.html
Accepting Students For:
Rotation, Spring
Rotation, Winter
Research Summary
His research program focuses on defining the intracellular communication networks that promote specificity in signal transduction events. Dr. Scott’s lab has identified a family of A-kinase–anchoring proteins (AKAPs) that target the cAMP-dependent protein kinase (PKA) and other signaling enzymes to specific subcellular sites. AKAPs influence the regulation of physiological processes by bringing enzymes close to their appropriate effectors and substrates at precisely the right moment. Dr. Scott and his lab have made significant progress on establishing the AKAP model, the functional consequence