faculty

Jesse Bloom

jbloom@fredhutch.org

Fred Hutch, 

Computational Biology (Area Director)

Genetics, Genomics & Evolution

Microbiology, Infection & Immunity

The evolution of proteins and viruses

Faculty Contact Information

Building: Weintraub Room: B3-160 Box: A3-020 http://research.fhcrc.org/bloom/en.html

Lab Information

Location: Fred Hutch Building: Weintraub building Room: B3-123 Phone: 206-667-3603 http://research.fhcrc.org/bloom/en.html

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Publications

Reconciling disparate estimates of viral genetic diversity during human influenza infections.

Xue KS, Bloom JD.

Nature genetics. 2019;

PubMed [journal]
PMID:
30804564

An Antigenic Atlas of HIV-1 Escape from Broadly Neutralizing Antibodies Distinguishes Functional and Structural Epitopes.

Dingens AS, Arenz D, Weight H, Overbaugh J, Bloom JD.

Immunity. 2019; 50(2):520-532.e3.

PubMed [journal]
PMID:
30709739

Comprehensive profiling of translation initiation in influenza virus infected cells.

Machkovech HM, Bloom JD, Subramaniam AR.

PLoS pathogens. 2019; 15(1):e1007518.

PubMed [journal]
PMID:
30673779
PMCID:
PMC6361465

Modeling site-specific amino-acid preferences deepens phylogenetic estimates of viral sequence divergence.

Hilton SK, Bloom JD.

Virus evolution. 2018; 4(2):vey033.

PubMed [journal]
PMID:
30425841
PMCID:
PMC6220371

Characterization of Influenza B Virus Variants with Reduced Neuraminidase Inhibitor Susceptibility.

Farrukee R, Zarebski AE, McCaw JM, Bloom JD, Reading PC, Hurt AC.

Antimicrobial agents and chemotherapy. 2018; 62(11).

PubMed [journal]
PMID:
30201817
PMCID:
PMC6201084

Research Summary

We use a combination of experimental and computational approaches to study molecular evolution. We especially focus on viruses such as influenza.