Michael Lagunoff

Isolation and characterization of circulating lymphatic endothelial colony forming cells.

DiMaio TA, Wentz BL, Lagunoff M.

Exp Cell Res. 2016 Jan 1; 1(340)159-69

Latent KSHV Infected Endothelial Cells Are Glutamine Addicted and Require Glutaminolysis for Survival.

Sanchez EL, Carroll PA, Thalhofer AB, Lagunoff M.

PLoS Pathog. 2015 Jul; 7(11)e1005052

Viral activation of cellular metabolism.

Sanchez EL, Lagunoff M.

Virology. 2015 May; (479-480)609-18

Nelfinavir impairs glycosylation of herpes simplex virus 1 envelope proteins and blocks virus maturation.

Gantt S, Gachelet E, Carlsson J, Barcy S, Casper C, Lagunoff M.

Adv Virol. 2015; (2015)687162

KSHV-TK: thymidine kinase or tyrosine kinase?

Lagunoff M

EMBO J. 2015 Feb 12; 4(34)427-9

Dengue virus induces and requires glycolysis for optimal replication.

Fontaine KA, Sanchez EL, Camarda R, Lagunoff M.

J Virol. 2015 Feb; 4(89)2358-66

Kaposi's sarcoma-associated herpesvirus downregulates transforming growth factor β2 to promote enhanced stability of capillary-like tube formation.

DiMaio TA, Gutierrez KD, Lagunoff M.

J Virol. 2014 Dec; 24(88)14301-9

Nuclear factor kappa B is required for the production of infectious human herpesvirus 8 virions.

Blattman NN, Lagunoff M, Blattman JN, Corey L.

Front Microbiol. 2014; (5)129

Vaccinia virus requires glutamine but not glucose for efficient replication.

Fontaine KA, Camarda R, Lagunoff M.

J Virol. 2014 Apr; 8(88)4366-74

Ets-1 is required for the activation of VEGFR3 during latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells.

Gutierrez KD, Morris VA, Wu D, Barcy S, Lagunoff M.

J Virol. 2013 Jun; 12(87)6758-68

Global metabolic profiling of infection by an oncogenic virus: KSHV induces and requires lipogenesis for survival of latent infection.

Delgado T, Sanchez EL, Camarda R, Lagunoff M.

PLoS Pathog. 2012; 8(8)e1002866

The KSHV viral IL-6 homolog is sufficient to induce blood to lymphatic endothelial cell differentiation.

Morris VA, Punjabi AS, Wells RC, Wittkopp CJ, Vart R, Lagunoff M.

Virology. 2012 Jul 5; 2(428)112-20

KSHV Induction of Angiogenic and Lymphangiogenic Phenotypes.

Dimaio TA, Lagunoff M.

Front Microbiol. 2012; (3)102

Latent KSHV infection of endothelial cells induces integrin beta3 to activate angiogenic phenotypes.

DiMaio TA, Gutierrez KD, Lagunoff M.

PLoS Pathog. 2011 Dec; 12(7)e1002424

The HIV protease inhibitor nelfinavir inhibits Kaposi's sarcoma-associated herpesvirus replication in vitro.

Gantt S, Carlsson J, Ikoma M, Gachelet E, Gray M, Geballe AP, Corey L, Casper C, Lagunoff M, Vieira J.

Antimicrob Agents Chemother. 2011 Jun; 6(55)2696-703

Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells.

Delgado T, Carroll PA, Punjabi AS, Margineantu D, Hockenbery DM, Lagunoff M.

Proc Natl Acad Sci U S A. 2010 Jun 8; 23(107)10696-701

Activation of Akt through gp130 receptor signaling is required for Kaposi's sarcoma-associated herpesvirus-induced lymphatic reprogramming of endothelial cells.

Morris VA, Punjabi AS, Lagunoff M.

J Virol. 2008 Sep; 17(82)8771-9

CD8 T cell control of HSV reactivation from latency is abrogated by viral inhibition of MHC class I.

Orr MT, Mathis MA, Lagunoff M, Sacks JA, Wilson CB.

Cell Host Microbe. 2007 Sep 13; 3(2)172-80

Persistent activation of STAT3 by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells.

Punjabi AS, Carroll PA, Chen L, Lagunoff M.

J Virol. 2007 Mar; 5(81)2449-58

The KSHV viral interleukin-6 is not essential for latency or lytic replication in BJAB cells.

Chen L, Lagunoff M.

Virology. 2007 Mar 15; 2(359)425-35

The insulin receptor is essential for virus-induced tumorigenesis of Kaposi's sarcoma.

Rose PP, Carroll JM, Carroll PA, DeFilippis VR, Lagunoff M, Moses AV, Roberts CT Jr, Früh K.

Oncogene. 2007 Mar 29; 14(26)1995-2005

Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors.

Carroll PA, Kenerson HL, Yeung RS, Lagunoff M.

J Virol. 2006 Nov; 21(80)10802-12

Establishment and maintenance of Kaposi's sarcoma-associated herpesvirus latency in B cells.

Chen L, Lagunoff M.

J Virol. 2005 Nov; 22(79)14383-91

Kaposi's sarcoma-associated herpesvirus infection of blood endothelial cells induces lymphatic differentiation.

Carroll PA, Brazeau E, Lagunoff M.

Virology. 2004 Oct 10; 1(328)7-18

Inhibition of apoptosis by the gamma-herpesviruses.

Lagunoff M, Carroll PA.

Int Rev Immunol. 2003 Sep-Dec; 5-6(22)373-99

De novo infection and serial transmission of Kaposi's sarcoma-associated herpesvirus in cultured endothelial cells.

Lagunoff M, Bechtel J, Venetsanakos E, Roy AM, Abbey N, Herndier B, McMahon M, Ganem D.

J Virol. 2002 Mar; 5(76)2440-8

Immunoreceptor tyrosine-based activation motif-dependent signaling by Kaposi's sarcoma-associated herpesvirus K1 protein: effects on lytic viral replication.

Lagunoff M, Lukac DM, Ganem D.

J Virol. 2001 Jul; 13(75)5891-8

Herpes simplex virus 1 open reading frames O and P are not necessary for establishment of latent infection in mice.

Randall G, Lagunoff M, Roizman B.

J Virol. 2000 Oct; 19(74)9019-27

Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposi's sarcoma (KS)-associated herpesvirus: implications for KS pathogenesis.

Kirshner JR, Staskus K, Haase A, Lagunoff M, Ganem D.

J Virol. 1999 Jul; 7(73)6006-14

Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus.

Lagunoff M, Majeti R, Weiss A, Ganem D.

Proc Natl Acad Sci U S A. 1999 May 11; 10(96)5704-9

A cluster of latently expressed genes in Kaposi's sarcoma-associated herpesvirus.

Dittmer D, Lagunoff M, Renne R, Staskus K, Haase A, Ganem D.

J Virol. 1998 Oct; 10(72)8309-15

Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus.

Kedes DH, Lagunoff M, Renne R, Ganem D.

J Clin Invest. 1997 Nov 15; 10(100)2606-10

The structure and coding organization of the genomic termini of Kaposi's sarcoma-associated herpesvirus.

Lagunoff M, Ganem D.

Virology. 1997 Sep 15; 1(236)147-54

The product of ORF O located within the domain of herpes simplex virus 1 genome transcribed during latent infection binds to and inhibits in vitro binding of infected cell protein 4 to its cognate DNA site.

Randall G, Lagunoff M, Roizman B.

Proc Natl Acad Sci U S A. 1997 Sep 16; 19(94)10379-84

The protease and the assembly protein of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8).

Unal A, Pray TR, Lagunoff M, Pennington MW, Ganem D, Craik CS.

J Virol. 1997 Sep; 9(71)7030-8

The size and conformation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in infected cells and virions.

Renne R, Lagunoff M, Zhong W, Ganem D.

J Virol. 1996 Nov; 11(70)8151-4

Phenotypic properties of herpes simplex virus 1 containing a derepressed open reading frame P gene.

Lagunoff M, Randall G, Roizman B.

J Virol. 1996 Mar; 3(70)1810-7

The regulation of synthesis and properties of the protein product of open reading frame P of the herpes simplex virus 1 genome.

Lagunoff M, Roizman B.

J Virol. 1995 Jun; 6(69)3615-23

Two overlapping transcription units which extend across the L-S junction of herpes simplex virus type 1.

Bohenzky RA, Lagunoff M, Roizman B, Wagner EK, Silverstein S.

J Virol. 1995 May; 5(69)2889-97

Expression of a herpes simplex virus 1 open reading frame antisense to the gamma(1)34.5 gene and transcribed by an RNA 3' coterminal with the unspliced latency-associated transcript.

Lagunoff M, Roizman B.

J Virol. 1994 Sep; 9(68)6021-8