James Zimring

Alloimmunogenicity of an isolated MHC allele is affected by the context of MHC mismatch in a murine model.

Hudson KE, Wong ASL, Richards AL, Kapp LM, Zimring JC.

Transfusion. 2019 Feb; 2(59)744-753

Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS-III-Omics.

D'Alessandro A, Culp-Hill R, Reisz JA, Anderson M, Fu X, Nemkov T, Gehrke S, Zheng C, Kanias T, Guo Y, Page G, Gladwin MT, Kleinman S, Lanteri M, Stone M, Busch M, Zimring JC, Recipient Epidemiology and Donor Evaluation Study-III (REDS-III)..

Transfusion. 2019 Jan; 1(59)89-100

Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells.

Reisz JA, Nemkov T, Dzieciatkowska M, Culp-Hill R, Stefanoni D, Hill RC, Yoshida T, Dunham A, Kanias T, Dumont LJ, Busch M, Eisenmesser EZ, Zimring JC, Hansen KC, D'Alessandro A.

Transfusion. 2018 Dec; 12(58)2978-2991

Red blood cells as an organ? How deep omics characterization of the most abundant cell in the human body highlights other systemic metabolic functions beyond oxygen transport.

Nemkov T, Reisz JA, Xia Y, Zimring JC, D'Alessandro A.

Expert Rev Proteomics. 2018 Nov; 11(15)855-864

The clinical impact of glucose-6-phosphate dehydrogenase deficiency in patients with sickle cell disease.

Karafin MS, Fu X, D'Alessandro A, Thomas T, Hod EA, Zimring JC, Field JJ, Francis RO.

Curr Opin Hematol. 2018 Nov; 6(25)494-499

Identification of IgG3-specific epitope that remedies problem in diagnostic IgG subclass determination due to human genetic variation.

Howie HL, Wang X, Kapp L, Lebedev JN, Zimring JC.

J Clin Pathol. 2018 Jun; 6(71)559-561

A unique major histocompatibility complex Class II-binding register correlates with HLA-DR11-associated immunogenicity of the major K blood group antigen.

Gunasekera D, Zimring JC, Pratt KP.

Transfusion. 2018 May; 5(58)1171-1181

Common murine immunoglobulin detection reagents have diminished reactivity with IgG3 - A vulnerability to misinterpretation.

Howie HL, Wang X, Kapp L, Lebedev J, Hudson KE, Zimring JC.

J Immunol Methods. 2018 Apr; (455)10-13

Peritransplantation Red Blood Cell Transfusion Is Associated with Increased Risk of Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.

Hosoba S, Waller EK, Shenvi N, Graiser M, Easley KA, Al-Kadhimi Z, Andoh A, Antun AG, Barclay S, Josephson CD, Koff JL, Khoury HJ, Langston AA, Zimring JC, Roback JD, Giver CR.

Biol Blood Marrow Transplant. 2018 May; 5(24)973-982

Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016.

Vostal JG, Buehler PW, Gelderman MP, Alayash AI, Doctor A, Zimring JC, Glynn SA, Hess JR, Klein H, Acker JP, Spinella PC, D'Alessandro A, Palsson B, Raife TJ, Busch MP, McMahon TJ, Intaglietta M, Swartz HM, Dubick MA, Cardin S, Patel RP, Natanson C, Weisel JW, Muszynski JA, Norris PJ, Ness PM.

Transfusion. 2018 Jan; 1(58)255-266

Antibodies to Senescent Antigen and C3 Are Not Required for Normal Red Blood Cell Lifespan in a Murine Model.

Hudson KE, de Wolski K, Kapp LM, Richards AL, Schniederjan MJ, Zimring JC.

Front Immunol. 2017; (8)1425

Innate B-1 B Cells Are Not Enriched in Red Blood Cell Autoimmune Mice: Importance of B Cell Receptor Transgenic Selection.

Richards AL, Howie HL, Kapp LM, Hendrickson JE, Zimring JC, Hudson KE.

Front Immunol. 2017; (8)1366

Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage.

Nemkov T, Sun K, Reisz JA, Song A, Yoshida T, Dunham A, Wither MJ, Francis RO, Roach RC, Dzieciatkowska M, Rogers SC, Doctor A, Kriebardis A, Antonelou M, Papassideri I, Young CT, Thomas TA, Hansen KC, Spitalnik SL, Xia Y, Zimring JC, Hod EA, D'Alessandro A.

Haematologica. 2018 Feb; 2(103)361-372

Murine red blood cells from genetically distinct donors cross-regulate when stored together.

Hay A, Howie HL, Waterman HR, de Wolski K, Zimring JC.

Transfusion. 2017 Nov; 11(57)2657-2664

Errors in data interpretation from genetic variation of human analytes.

Howie HL, Delaney M, Wang X, Er LS, Kapp L, Lebedev JN, Zimring JC.

JCI Insight. 2017 Jul 6; 13(2)

Type I IFN Is Necessary and Sufficient for Inflammation-Induced Red Blood Cell Alloimmunization in Mice.

Gibb DR, Liu J, Natarajan P, Santhanakrishnan M, Madrid DJ, Eisenbarth SC, Zimring JC, Iwasaki A, Hendrickson JE.

J Immunol. 2017 Aug 1; 3(199)1041-1050

Iron-deficient erythropoiesis in blood donors and red blood cell recovery after transfusion: initial studies with a mouse model.

Bandyopadhyay S, Brittenham GM, Francis RO, Zimring JC, Hod EA, Spitalnik SL.

Blood Transfus. 2017 Mar; 2(15)158-164

Large retrospective effects, clear differences in animals, and multiple negative randomised controlled trials: this is exactly how it is supposed to work.

Zimring JC, Spitalnik SL.

Blood Transfus. 2017 Mar; 2(15)104-106

Antigen Density Dictates Immune Responsiveness following Red Blood Cell Transfusion.

Arthur CM, Patel SR, Smith NH, Bennett A, Kamili NA, Mener A, Gerner-Smidt C, Sullivan HC, Hale JS, Wieland A, Youngblood B, Zimring JC, Hendrickson JE, Stowell SR.

J Immunol. 2017 Apr 1; 7(198)2671-2680

Cellular immune responses in red blood cell alloimmunization.

Zimring JC, Hudson KE.

Hematology Am Soc Hematol Educ Program. 2016 Dec 2; 1(2016)452-456

Interleukin-6 receptor-alpha signaling drives anti-RBC alloantibody production and T-follicular helper cell differentiation in a murine model of red blood cell alloimmunization.

Arneja A, Salazar JE, Jiang W, Hendrickson JE, Zimring JC, Luckey CJ.

Haematologica. 2016 Nov; 11(101)e440-e444

Serological blind spots for variants of human IgG3 and IgG4 by a commonly used anti-immunoglobulin reagent.

Howie HL, Delaney M, Wang X, Er LS, Vidarsson G, Stegmann TC, Kapp L, Lebedev JN, Wu Y, AuBuchon JP, Zimring JC.

Transfusion. 2016 Dec; 12(56)2953-2962

Scientific advances: Fallacy of perfection harms peer review.

Zimring JC, Spitalnik SL.

Nature. 2016 Sep 1; 7618(537)34

Bioactive lipids accumulate in stored red blood cells despite leukoreduction: a targeted metabolomics study.

Fu X, Felcyn JR, Odem-Davis K, Zimring JC.

Transfusion. 2016 Oct; 10(56)2560-2570

Testosterone-dependent sex differences in red blood cell hemolysis in storage, stress, and disease.

Kanias T, Sinchar D, Osei-Hwedieh D, Baust JJ, Jordan A, Zimring JC, Waterman HR, de Wolski KS, Acker JP, Gladwin MT.

Transfusion. 2016 Oct; 10(56)2571-2583

The Nlrp3 Inflammasome Does Not Regulate Alloimmunization to Transfused Red Blood Cells in Mice.

Gibb DR, Calabro S, Liu D, Tormey CA, Spitalnik SL, Zimring JC, Hendrickson JE, Hod EA, Eisenbarth SC.

EBioMedicine. 2016 Jul; (9)77-86

Bridging channel dendritic cells induce immunity to transfused red blood cells.

Calabro S, Gallman A, Gowthaman U, Liu D, Chen P, Liu J, Krishnaswamy JK, Nascimento MS, Xu L, Patel SR, Williams A, Tormey CA, Hod EA, Spitalnik SL, Zimring JC, Hendrickson JE, Stowell SR, Eisenbarth SC.

J Exp Med. 2016 May 30; 6(213)887-96

Metabolites in stored platelets associated with platelet recoveries and survivals.

Zimring JC, Slichter S, Odem-Davis K, Felcyn JR, Kapp LM, Bell LN, Gunst PR, Corson J, Jones MK, Pellham E, Bailey SL, Fu X.

Transfusion. 2016 Aug; 8(56)1974-83

Lost in translation: signal and frequency amplification in animal modeling.

Zimring JC, Spitalnik SL, Odem-Davis K.

Transfusion. 2016 Mar; 3(56)773-4

Metabolic pathways that correlate with post-transfusion circulation of stored murine red blood cells.

de Wolski K, Fu X, Dumont LJ, Roback JD, Waterman H, Odem-Davis K, Howie HL, Zimring JC.

Haematologica. 2016 May; 5(101)578-86

Erythrophagocytosis by plasmacytoid dendritic cells and monocytes is enhanced during inflammation.

Richards AL, Hendrickson JE, Zimring JC, Hudson KE.

Transfusion. 2016 Apr; 4(56)905-16

Does AC stand for acylcarnitine, anticoagulant, or both?

Zimring JC

Blood. 2015 Sep 24; 13(126)1524-5

Transfusion-induced alloimmunization and platelet refractoriness in a mouse model: mechanisms and interventions.

Waterman HR, Kapp LM, Munday A, Odem-Davis K, Zimring JC.

Transfusion. 2016 Jan; 1(56)91-100

2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium.

Spitalnik SL, Triulzi D, Devine DV, Dzik WH, Eder AF, Gernsheimer T, Josephson CD, Kor DJ, Luban NL, Roubinian NH, Mondoro T, Welniak LA, Zou S, Glynn S, State of the Science in Transfusion Medicine Working Groups..

Transfusion. 2015 Sep; 9(55)2282-90

IgG-Mediated Immune Suppression to Erythrocytes by Polyclonal Antibodies Can Occur in the Absence of Activating or Inhibitory Fcγ Receptors in a Full Mouse Model.

Bernardo L, Yu H, Amash A, Zimring JC, Lazarus AH.

J Immunol. 2015 Sep 1; 5(195)2224-30

Anti-KEL sera prevents alloimmunization to transfused KEL RBCs in a murine model.

Stowell SR, Arthur CM, Girard-Pierce KR, Sullivan HC, Santhanakrishnan M, Natarajan P, Patel SR, Tormey CA, Zimring JC, Hendrickson JE.

Haematologica. 2015 Oct; 10(100)e394-7

Do immune complexes play a role in hemolytic sequelae of intravenous immune globulin?

Zimring JC

Transfusion. 2015 Jul; (55 Suppl 2)S86-9

Widening our gaze of red blood storage haze: a role for metabolomics.

Zimring JC

Transfusion. 2015 Jun; 6(55)1139-42

Analysis of 24-h recovery of transfused stored RBCs in recipient mice of distinct genetic backgrounds.

Waterman HR, Kapp LM, Howie HL, Hod EA, Spitalnik SL, Zimring JC.

Vox Sang. 2015 Aug; 2(109)148-54

Factors Influencing RBC Alloimmunization: Lessons Learned from Murine Models.

Ryder AB, Zimring JC, Hendrickson JE.

Transfus Med Hemother. 2014 Nov; 6(41)406-19

Established and theoretical factors to consider in assessing the red cell storage lesion.

Zimring JC

Blood. 2015 Apr 2; 14(125)2185-90

Pathobiology of transfusion reactions.

Zimring JC, Spitalnik SL.

Annu Rev Pathol. 2015; (10)83-110

Complex changes in von Willebrand factor-associated parameters are acquired during uncomplicated pregnancy.

Drury-Stewart DN, Lannert KW, Chung DW, Teramura GT, Zimring JC, Konkle BA, Gammill HS, Johnsen JM.

PLoS One. 2014; 11(9)e112935

The fat and the skinny on acute lung injury.

Zimring JC

Blood. 2014 Oct 23; 17(124)2617-8

Antibody-mediated immune suppression of erythrocyte alloimmunization can occur independently from red cell clearance or epitope masking in a murine model.

Yu H, Stowell SR, Bernardo L, Hendrickson JE, Zimring JC, Amash A, Uchikawa M, Lazarus AH.

J Immunol. 2014 Sep 15; 6(193)2902-10

Macrophages clear refrigerator storage-damaged red blood cells and subsequently secrete cytokines in vivo, but not in vitro, in a murine model.

Wojczyk BS, Kim N, Bandyopadhyay S, Francis RO, Zimring JC, Hod EA, Spitalnik SL.

Transfusion. 2014 Dec; 12(54)3186-97

Metabolomics of ADSOL (AS-1) red blood cell storage.

Roback JD, Josephson CD, Waller EK, Newman JL, Karatela S, Uppal K, Jones DP, Zimring JC, Dumont LJ.

Transfus Med Rev. 2014 Apr; 2(28)41-55

Fresh versus old blood: are there differences and do they matter?

Zimring JC

Hematology Am Soc Hematol Educ Program. 2013; (2013)651-5

Antigen modulation confers protection to red blood cells from antibody through Fcγ receptor ligation.

Stowell SR, Liepkalns JS, Hendrickson JE, Girard-Pierce KR, Smith NH, Arthur CM, Zimring JC.

J Immunol. 2013 Nov 15; 10(191)5013-25

Transfusion-induced bone marrow transplant rejection due to minor histocompatibility antigens.

Patel SR, Zimring JC.

Transfus Med Rev. 2013 Oct; 4(27)241-8

A novel role for C3 in antibody-induced red blood cell clearance and antigen modulation.

Girard-Pierce KR, Stowell SR, Smith NH, Arthur CM, Sullivan HC, Hendrickson JE, Zimring JC.

Blood. 2013 Sep 5; 10(122)1793-801

Glucose-6-phosphate dehydrogenase deficiency in transfusion medicine: the unknown risks.

Francis RO, Jhang JS, Pham HP, Hod EA, Zimring JC, Spitalnik SL.

Vox Sang. 2013 Nov; 4(105)271-82

Alloantibodies to a paternally derived RBC KEL antigen lead to hemolytic disease of the fetus/newborn in a murine model.

Stowell SR, Henry KL, Smith NH, Hudson KE, Halverson GR, Park JC, Bennett AM, Girard-Pierce KR, Arthur CM, Bunting ST, Zimring JC, Hendrickson JE.

Blood. 2013 Aug 22; 8(122)1494-504

Resolution of translation start site for the human Kell glycoprotein.

Blacken GR, Zimring JC, Fu X.

Transfusion. 2013 Nov; 11 Suppl 2(53)2882-6

Strain-specific red blood cell storage, metabolism, and eicosanoid generation in a mouse model.

Zimring JC, Smith N, Stowell SR, Johnsen JM, Bell LN, Francis RO, Hod EA, Hendrickson JE, Roback JD, Spitalnik SL.

Transfusion. 2014 Jan; 1(54)137-48

Transfusion of murine red blood cells expressing the human KEL glycoprotein induces clinically significant alloantibodies.

Stowell SR, Girard-Pierce KR, Smith NH, Henry KL, Arthur CM, Zimring JC, Hendrickson JE.

Transfusion. 2014 Jan; 1(54)179-89

On the appropriate use and interpretation of animal models in transfusion medicine research.

Zimring JC, Spitalnik SL.

Transfusion. 2013 Oct; 10(53)2334-9

Location, location, location: advancing veto cell therapies.

Zimring JC

Blood. 2013 Feb 14; 7(121)1069-70

Addition of ascorbic acid solution to stored murine red blood cells increases posttransfusion recovery and decreases microparticles and alloimmunization.

Stowell SR, Smith NH, Zimring JC, Fu X, Palmer AF, Fontes J, Banerjee U, Yazer MH.

Transfusion. 2013 Oct; 10(53)2248-57

Initiation and regulation of complement during hemolytic transfusion reactions.

Stowell SR, Winkler AM, Maier CL, Arthur CM, Smith NH, Girard-Pierce KR, Cummings RD, Zimring JC, Hendrickson JE.

Clin Dev Immunol. 2012; (2012)307093

Resistance of a subset of red blood cells to clearance by antibodies in a mouse model of incompatible transfusion.

Liepkalns JS, Cadwell CM, Stowell SR, Hod EA, Spitalnik SL, Zimring JC.

Transfusion. 2013 Jun; 6(53)1319-27

Frequency of glucose-6-phosphate dehydrogenase-deficient red blood cell units in a metropolitan transfusion service.

Francis RO, Jhang J, Hendrickson JE, Zimring JC, Hod EA, Spitalnik SL.

Transfusion. 2013 Mar; 3(53)606-11

Partial tolerance of autoreactive B and T cells to erythrocyte-specific self-antigens in mice.

Hudson KE, Hendrickson JE, Cadwell CM, Iwakoshi NN, Zimring JC.

Haematologica. 2012 Dec; 12(97)1836-44

Effects of genetic, epigenetic, and environmental factors on alloimmunization to transfused antigens: Current paradigms and future considerations.

Zimring JC, Stowell SR, Johnsen JM, Hendrickson JE.

Transfus Clin Biol. 2012 Jun; 3(19)125-31

Keeping the Kell away from immunity.

Zimring JC, Johnsen JM.

Blood. 2012 Jun 7; 23(119)5346-8

Biphasic clearance of incompatible red blood cells through a novel mechanism requiring neither complement nor Fcγ receptors in a murine model.

Liepkalns JS, Hod EA, Stowell SR, Cadwell CM, Spitalnik SL, Zimring JC.

Transfusion. 2012 Dec; 12(52)2631-45

Generation of transgenic mice with antithetical KEL1 and KEL2 human blood group antigens on red blood cells.

Smith NH, Henry KL, Cadwell CM, Bennett A, Hendrickson JE, Frame T, Zimring JC.

Transfusion. 2012 Dec; 12(52)2620-30

CTLA4-Ig prevents alloantibody production and BMT rejection in response to platelet transfusions in mice.

Gilson CR, Patel SR, Zimring JC.

Transfusion. 2012 Oct; 10(52)2209-19

Mechanisms of alloimmunization and subsequent bone marrow transplantation rejection induced by platelet transfusion in a murine model.

Patel SR, Smith NH, Kapp L, Zimring JC.

Am J Transplant. 2012 May; 5(12)1102-12

Transfusion in the absence of inflammation induces antigen-specific tolerance to murine RBCs.

Smith NH, Hod EA, Spitalnik SL, Zimring JC, Hendrickson JE.

Blood. 2012 Feb 9; 6(119)1566-9

Transfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non-transferrin-bound iron.

Hod EA, Brittenham GM, Billote GB, Francis RO, Ginzburg YZ, Hendrickson JE, Jhang J, Schwartz J, Sharma S, Sheth S, Sireci AN, Stephens HL, Stotler BA, Wojczyk BS, Zimring JC, Spitalnik SL.

Blood. 2011 Dec 15; 25(118)6675-82

Alloimmunization to transfused platelets requires priming of CD4+ T cells in the splenic microenvironment in a murine model.

Gilson CR, Zimring JC.

Transfusion. 2012 Apr; 4(52)849-59

Minor antigens on transfused RBCs crossprime CD8 T cells but do not induce full effector function.

Desmarets M, Mylvaganam G, Waller EK, Josephson CD, Pack C, Lukacher AE, Zimring JC.

Am J Transplant. 2011 Sep; 9(11)1825-34

Alloimmunization to transfused HOD red blood cells is not increased in mice with sickle cell disease.

Hendrickson JE, Hod EA, Perry JR, Ghosh S, Chappa P, Adisa O, Kean LS, Ofori-Acquah SF, Archer DR, Spitalnik SL, Zimring JC.

Transfusion. 2012 Feb; 2(52)231-40

Transfusion of fresh murine red blood cells reverses adverse effects of older stored red blood cells.

Hendrickson JE, Hod EA, Hudson KE, Spitalnik SL, Zimring JC.

Transfusion. 2011 Dec; 12(51)2695-702

Rapid clearance of transfused murine red blood cells is associated with recipient cytokine storm and enhanced alloimmunogenicity.

Hendrickson JE, Hod EA, Cadwell CM, Eisenbarth SC, Spiegel DA, Tormey CA, Spitalnik SL, Zimring JC.

Transfusion. 2011 Nov; 11(51)2445-54

Alloimmunization against RBC or PLT antigens is independent of TRIM21 expression in a murine model.

Patel SR, Hendrickson JE, Smith NH, Cadwell CM, Ozato K, Morse HC 3rd, Yoshimi R, Zimring JC.

Mol Immunol. 2011 Mar; 6-7(48)909-13

Current problems and future directions of transfusion-induced alloimmunization: summary of an NHLBI working group.

Zimring JC, Welniak L, Semple JW, Ness PM, Slichter SJ, Spitalnik SL, NHLBI Alloimmunization Working Group..

Transfusion. 2011 Feb; 2(51)435-41

MHC II on transfused murine blood is not required for alloimmunization against MHC I.

Gilson CR, Cadwell CM, Smith NH, Hendrickson JE, Zimring JC.

Vox Sang. 2010 Nov; 4(99)369-74

Recent developments and future directions of alloimmunization to transfused blood products.

Zimring JC

Clin Lab Med. 2010 Jun; 2(30)467-73

Use of mouse models to study the mechanisms and consequences of RBC clearance.

Hod EA, Arinsburg SA, Francis RO, Hendrickson JE, Zimring JC, Spitalnik SL.

Vox Sang. 2010 Aug 1; 2(99)99-111

Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation.

Hod EA, Zhang N, Sokol SA, Wojczyk BS, Francis RO, Ansaldi D, Francis KP, Della-Latta P, Whittier S, Sheth S, Hendrickson JE, Zimring JC, Brittenham GM, Spitalnik SL.

Blood. 2010 May 27; 21(115)4284-92

Regulation of primary alloantibody response through antecedent exposure to a microbial T-cell epitope.

Hudson KE, Lin E, Hendrickson JE, Lukacher AE, Zimring JC.

Blood. 2010 May 13; 19(115)3989-96

Storage of murine red blood cells enhances alloantibody responses to an erythroid-specific model antigen.

Hendrickson JE, Hod EA, Spitalnik SL, Hillyer CD, Zimring JC.

Transfusion. 2010 Mar; 3(50)642-8

To RBC or not to RBC: the role of suicidal death in hemolytic transfusion reactions.

Zimring JC, Spitalnik SL.

Transfusion. 2009 Sep; 9(49)1776-8

Transfusion of minor histocompatibility antigen-mismatched platelets induces rejection of bone marrow transplants in mice.

Patel SR, Cadwell CM, Medford A, Zimring JC.

J Clin Invest. 2009 Sep; 9(119)2787-94

A novel mouse model of red blood cell storage and posttransfusion in vivo survival.

Gilson CR, Kraus TS, Hod EA, Hendrickson JE, Spitalnik SL, Hillyer CD, Shaz BH, Zimring JC.

Transfusion. 2009 Aug; 8(49)1546-53

Antigen loss from antibody-coated red blood cells.

Zimring JC, Cadwell CM, Spitalnik SL.

Transfus Med Rev. 2009 Jul; 3(23)189-204

Minor histocompatibility antigens on transfused leukoreduced units of red blood cells induce bone marrow transplant rejection in a mouse model.

Desmarets M, Cadwell CM, Peterson KR, Neades R, Zimring JC.

Blood. 2009 Sep 10; 11(114)2315-22

The spleen plays a central role in primary humoral alloimmunization to transfused mHEL red blood cells.

Hendrickson JE, Saakadze N, Cadwell CM, Upton JW, Mocarski ES, Hillyer CD, Zimring JC.

Transfusion. 2009 Aug; 8(49)1678-84

Does a febrile reaction to platelets predispose recipients to red blood cell alloimmunization?

Yazer MH, Triulzi DJ, Shaz B, Kraus T, Zimring JC.

Transfusion. 2009 Jun; 6(49)1070-5

An autoanti-Kp b immunoglobulin M that simulates antigen suppression.

Bosco A, Xenocostas A, Kinney J, Cadwell CM, Zimring JC.

Transfusion. 2009 Apr; 4(49)750-6

Animal models of transfusion-related acute lung injury.

Lögdberg LE, Vikulina T, Zimring JC, Hillyer CD.

Transfus Med Rev. 2009 Jan; 1(23)13-24

The role of inflammation in alloimmunization to antigens on transfused red blood cells.

Zimring JC, Hendrickson JE.

Curr Opin Hematol. 2008 Nov; 6(15)631-5

Lessons learned from mouse models of hemolytic transfusion reactions.

Hod EA, Zimring JC, Spitalnik SL.

Curr Opin Hematol. 2008 Nov; 6(15)601-5

Hypothesis: hemolytic transfusion reactions represent an alternative type of anaphylaxis.

Hod EA, Sokol SA, Zimring JC, Spitalnik SL.

Int J Clin Exp Pathol. 2009; 1(2)71-82

Blood donation and blood transfusion: special considerations for African Americans.

Shaz BH, Zimring JC, Demmons DG, Hillyer CD.

Transfus Med Rev. 2008 Jul; 3(22)202-14

Discrete Toll-like receptor agonists have differential effects on alloimmunization to transfused red blood cells.

Hendrickson JE, Roback JD, Hillyer CD, Easley KA, Zimring JC.

Transfusion. 2008 Sep; 9(48)1869-77

Cytokine storm in a mouse model of IgG-mediated hemolytic transfusion reactions.

Hod EA, Cadwell CM, Liepkalns JS, Zimring JC, Sokol SA, Schirmer DA, Jhang J, Spitalnik SL.

Blood. 2008 Aug 1; 3(112)891-4

Cross-linking induces non-haemolytic antigen-loss from transfused red blood cells: a potential role for rheumatoid factor.

Cadwell CM, Zimring JC.

Vox Sang. 2008 Aug; 2(95)159-62

Ovalbumin serves as a neo-transplantation antigen in retinal pigment epithelial cells.

Wajchman JR, Zimring JC, Lake JP, Wen J, Kapp JA.

Mol Vis. 2007 Oct 5; (13)1902-11

Transfusion-induced autoantibodies and differential immunogenicity of blood group antigens: a novel hypothesis.

Zimring JC, Spitalnik SL, Roback JD, Hillyer CD.

Transfusion. 2007 Dec; 12(47)2189-96

Inflammation enhances consumption and presentation of transfused RBC antigens by dendritic cells.

Hendrickson JE, Chadwick TE, Roback JD, Hillyer CD, Zimring JC.

Blood. 2007 Oct 1; 7(110)2736-43

Nonhemolytic antigen loss from red blood cells requires cooperative binding of multiple antibodies recognizing different epitopes.

Zimring JC, Cadwell CM, Chadwick TE, Spitalnik SL, Schirmer DA, Wu T, Parkos CA, Hillyer CD.

Blood. 2007 Sep 15; 6(110)2201-8

Analysis of CD8+ T cell-mediated anti-viral responses in mice with targeted deletions of the M1 or M5 muscarinic cholinergic receptors.

Vezys V, Masopust D, Desmarets M, Wess J, Zimring JC.

Life Sci. 2007 May 30; 24-25(80)2330-3

Transfusion-related acute lung injury.

Sheppard CA, Lögdberg LE, Zimring JC, Hillyer CD.

Hematol Oncol Clin North Am. 2007 Feb; 1(21)163-76

Transfusion-transmitted cytomegalovirus: lessons from a murine model.

Roback JD, Su L, Zimring JC, Hillyer CD.

Transfus Med Rev. 2007 Jan; 1(21)26-36

Recipient inflammation affects the frequency and magnitude of immunization to transfused red blood cells.

Hendrickson JE, Desmarets M, Deshpande SS, Chadwick TE, Hillyer CD, Roback JD, Zimring JC.

Transfusion. 2006 Sep; 9(46)1526-36

Performance characteristics of two real-time PCR assays for the quantification of Epstein-Barr virus DNA.

Hill CE, Harris SB, Culler EE, Zimring JC, Nolte FS, Caliendo AM.

Am J Clin Pathol. 2006 May; 5(125)665-71

Rapamycin prolongs susceptibility of responding T cells to tolerance induction by CD8+ veto cells.

Anderson KM, Zimring JC.

Transplantation. 2006 Jan 15; 1(81)88-94

Immunization to minor histocompatibility antigens on transfused RBCs through crosspriming into recipient MHC class I pathways.

Zimring JC, Hair GA, Deshpande SS, Horan JT.

Blood. 2006 Jan 1; 1(107)187-9

Regulation of CD8+ cytolytic T lymphocyte differentiation by a cholinergic pathway.

Zimring JC, Kapp LM, Yamada M, Wess J, Kapp JA.

J Neuroimmunol. 2005 Jul; 1-2(164)66-75

Nonhemolytic antibody-induced loss of erythrocyte surface antigen.

Zimring JC, Hair GA, Chadwick TE, Deshpande SS, Anderson KM, Hillyer CD, Roback JD.

Blood. 2005 Aug 1; 3(106)1105-12

Effect of mediators of innate immunity and inflammation on CD8+ veto cells.

Zimring JC, Chadwick TE, Hillyer CD, Roback JD.

Transplantation. 2004 Dec 15; 11(78)1597-600

Appropriate use of recombinant factor VIIa: an expanding and unanswered question.

Zimring JC

Transfusion. 2004 Nov; 11(44)1544-6

Identification and characterization of CD8+ suppressor T cells.

Zimring JC, Kapp JA.

Immunol Res. 2004; 1-3(29)303-12

Short duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interferon in BCBL-1 cells.

Pozharskaya VP, Weakland LL, Zimring JC, Krug LT, Unger ER, Neisch A, Joshi H, Inoue N, Offermann MK.

J Virol. 2004 Jun; 12(78)6621-35

CD75s is a marker of murine CD8(+) suppressor T cells.

Zimring JC, Levery SB, Kniep B, Kapp LM, Fuller M, Kapp JA.

Int Immunol. 2003 Nov; 11(15)1389-99

Transcriptional activation by the human herpesvirus-8-encoded interferon regulatory factor.

Roan F, Zimring JC, Goodbourn S, Offermann MK.

J Gen Virol. 1999 Aug; (80 ( Pt 8))2205-9

CD40 ligation induced phenotypic and functional expression of CD80 by human cardiac microvascular endothelial cells.

Jollow KC, Zimring JC, Sundstrom JB, Ansari AA.

Transplantation. 1999 Aug 15; 3(68)430-9

Human herpesvirus 8 encodes an interferon regulatory factor (IRF) homolog that represses IRF-1-mediated transcription.

Zimring JC, Goodbourn S, Offermann MK.

J Virol. 1998 Jan; 1(72)701-7