Trisha Davis
tdavis@uw.eduUniversity of Washington,
Cancer Biology
Gene Expression, Cell Cycle & Chromosome Biology
Genetics, Genomics & Evolution
Biochemical and biophysical analysis of mitosis
Faculty Contact Information
Lab Information
Accepting Students For:
Publications
DaRosa PA, Harrison JS, Zelter A, Davis TN, Brzovic P, Kuhlman B, Klevit RE.
Molecular cell. 2018; 72(4):753-765.e6. NIHMSID: NIHMS1507957
- PMID:
- 30392931
- PMCID:
- PMC6239910
Helgeson LA, Zelter A, Riffle M, MacCoss MJ, Asbury CL, Davis TN.
Proceedings of the National Academy of Sciences of the United States of America. 2018; 115(11):2740-2745.
- PMID:
- 29487209
- PMCID:
- PMC5856539
Luan Q, Zelter A, MacCoss MJ, Davis TN, Nolen BJ.
Proceedings of the National Academy of Sciences of the United States of America. 2018; 115(7):E1409-E1418.
- PMID:
- 29386393
- PMCID:
- PMC5816175
Viswanath S, Bonomi M, Kim SJ, Klenchin VA, Taylor KC, Yabut KC, Umbreit NT, Van Epps HA, Meehl J, Jones MH, Russel D, Velazquez-Muriel JA, Winey M, Rayment I, Davis TN, Sali A, Muller EG.
Molecular biology of the cell. 2017; 28(23):3298-3314.
- PMID:
- 28814505
- PMCID:
- PMC5687031
Direct measurement of the strength of microtubule attachment to yeast centrosomes.
Fong KK, Sarangapani KK, Yusko EC, Riffle M, Llauró A, Graczyk B, Davis TN, Asbury CL.
Molecular biology of the cell. 2017; 28(14):1853-1861.
- PMID:
- 28331072
- PMCID:
- PMC5541836
Bickhart DM, Rosen BD, Koren S, Sayre BL, Hastie AR, Chan S, Lee J, Lam ET, Liachko I, Sullivan ST, Burton JN, Huson HJ, Nystrom JC, Kelley CM, Hutchison JL, Zhou Y, Sun J, Crisà A, Ponce de León FA, Schwartz JC, Hammond JA, Waldbieser GC, Schroeder SG, Liu GE, Dunham MJ, Shendure J, Sonstegard TS, Phillippy AM, Van Tassell CP, Smith TP.
Nature genetics. 2017; 49(4):643-650. NIHMSID: NIHMS956430
- PMID:
- 28263316
- PMCID:
- PMC5909822
The Ndc80 complex bridges two Dam1 complex rings.
Kim JO, Zelter A, Umbreit NT, Bollozos A, Riffle M, Johnson R, MacCoss MJ, Asbury CL, Davis TN.
eLife. 2017; 6.
- PMID:
- 28191870
- PMCID:
- PMC5354518
Corrigendum: Design of a hyperstable 60-subunit protein icosahedron.
Hsia Y, Bale JB, Gonen S, Shi D, Sheffler W, Fong KK, Nattermann U, Xu C, Huang PS, Ravichandran R, Yi S, Davis TN, Gonen T, King NP, Baker D.
Nature. 2016; 540(7631):150.
- PMID:
- 27760110
Berger S, Procko E, Margineantu D, Lee EF, Shen BW, Zelter A, Silva DA, Chawla K, Herold MJ, Garnier JM, Johnson R, MacCoss MJ, Lessene G, Davis TN, Stayton PS, Stoddard BL, Fairlie WD, Hockenbery DM, Baker D.
eLife. 2016; 5.
- PMID:
- 27805565
- PMCID:
- PMC5127641
Riffle M, Jaschob D, Zelter A, Davis TN.
Journal of proteome research. 2016; 15(8):2863-70.
- PMID:
- 27302480
- PMCID:
- PMC4977572
Research Summary
How does the cell ensure transmission of an exact complement of chromosomes each cell division? How does this process go awry in cancer cells? These are questions of interest to our lab. We use a variety of techniques from single-molecule biophysical approaches to biochemistry, genetics and microscopy to explore the regulation and action of the cell cycle machinery that ensures fidelity of chromosome segregation.