faculty

Kelly Lee

kklee@uw.edu
Associate Professor

University of Washington

Medical Chemistry

Biophysical and Structural Biology (Area Director)

Microbiology, Infection & Immunity

VIRUS STRUCTURE, DYNAMICS AND FUNCTION. MEMBRANE FUSION.

Faculty Contact Information

Building: Health Sciences Building Room: H-172J Box: 357610 Phone: 206-616-3972 http://faculty.washington.edu/kklee/Welcome.html

Research Summary

Viruses undergo dynamic structural reorganizations at many critical stages of their life cycles including during host cell invasion, membrane fusion, genome expulsion, assembly, and cell egress. The changes often involve concerted changes among hundreds of protein components and in the case of enveloped viruses, membranes as well. We use biophysical, structural, and biochemical techniques including cryo-EM, hydrogen/deuterium-exchange with mass spectrometry (HDX-MS), and small-angle X-ray scattering (SAXS) to understand these dynamic processes.

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Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Lab Information

Location: University of Washington
Building: Health Sciences Building
Room: H-053/H-059
Box: 357610
Phone: 206-616-3496
http://faculty.washington.edu/kklee/Welcome.html