University of Washington,
Developmental Biology, Stem Cells & Aging
Genetics, Genomics & Evolution
Development and application of proteomics technologies
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The focus of our research is in the development of stable isotope and mass spectrometry based approaches to improve our understanding of biology on a molecular, cellular, and whole organism level. Presently, individuals in the laboratory are working on technology for 1) automating biochemical sample preparation methods for the analysis of protein mixtures; 2) increasing the dynamic range of liquid chromatography-mass spectrometry for the analysis of peptides; and 3) developing computational tools for the automated conversion of mass spectrometry data into biologically meaningful results.