Ajay Dhaka
dhaka@uw.eduUniversity of Washington,
Developmental Biology, Stem Cells & Aging
Neuroscience
Neurobiology of touch, temperature and pain
Faculty Contact Information
Lab Information
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Publications
The following publications were retrieved from PubMed:
A zebrafish and mouse model for selective pruritus via direct activation of TRPA1.
Esancy K, Condon L, Feng J, Kimball C, Curtright A, Dhaka A.
Elife. 2018 Mar 21; (7)
Quantitative Analysis of Mouse Dural Afferent Neurons Expressing TRPM8, VGLUT3, and NF200.
Ren L, Chang MJ, Zhang Z, Dhaka A, Guo Z, Cao YQ.
Headache. 2018 Jan; 1(58)88-101
Gau P, Curtright A, Condon L, Raible DW, Dhaka A.
PLoS Genet. 2017 Jul; 7(13)e1006884
Vibhute AM, Dhaka A, Athiyarath V, Sureshan KM.
Chem Sci. 2016 Sep 1; 9(7)6282
A versatile glycosylation strategy <i>via</i> Au(iii) catalyzed activation of thioglycoside donors.
Vibhute AM, Dhaka A, Athiyarath V, Sureshan KM.
Chem Sci. 2016 Jul 1; 7(7)4259-4263
Exploration of millet models for developing nutrient rich graminaceous crops.
Muthamilarasan M, Dhaka A, Yadav R, Prasad M.
Plant Sci. 2016 Jan; (242)89-97
Function and postnatal changes of dural afferent fibers expressing TRPM8 channels.
Ren L, Dhaka A, Cao YQ.
Mol Pain. 2015 Jun 26; (11)37
Kimball C, Luo J, Yin S, Hu H, Dhaka A.
Mol Pharmacol. 2015 Jul; 1(88)131-8
Modeling nociception in zebrafish: a way forward for unbiased analgesic discovery.
Curtright A, Rosser M, Goh S, Keown B, Wagner E, Sharifi J, Raible DW, Dhaka A.
PLoS One. 2015; 1(10)e0116766
Singh J, Suhag M, Dhaka A.
Carbohydr Polym. 2015 Mar 6; (117)624-31
Brenner DS, Golden JP, Vogt SK, Dhaka A, Story GM, Gereau RW IV.
Pain. 2014 Oct; 10(155)2124-33
The zebrafish ortholog of TRPV1 is required for heat-induced locomotion.
Gau P, Poon J, Ufret-Vincenty C, Snelson CD, Gordon SE, Raible DW, Dhaka A.
J Neurosci. 2013 Mar 20; 12(33)5249-60
Huang D, Li S, Dhaka A, Story GM, Cao YQ.
Mol Pain. 2012 Sep 12; (8)66
Cooling-sensitive TRPM8 is thermostat of skin temperature against cooling.
Tajino K, Hosokawa H, Maegawa S, Matsumura K, Dhaka A, Kobayashi S.
PLoS One. 2011 Mar 2; 3(6)e17504
Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea.
Parra A, Madrid R, Echevarria D, del Olmo S, Morenilla-Palao C, Acosta MC, Gallar J, Dhaka A, Viana F, Belmonte C.
Nat Med. 2010 Dec; 12(16)1396-9
Fear learning and extinction are linked to neuronal plasticity through Rin1 signaling.
Bliss JM, Gray EE, Dhaka A, O'Dell TJ, Colicelli J.
J Neurosci Res. 2010 Mar; 4(88)917-26
Mandadi S, Nakanishi ST, Takashima Y, Dhaka A, Patapoutian A, McKemy DD, Whelan PJ.
Neuroscience. 2009 Sep 15; 4(162)1377-97
TRPV1 is activated by both acidic and basic pH.
Dhaka A, Uzzell V, Dubin AE, Mathur J, Petrus M, Bandell M, Patapoutian A.
J Neurosci. 2009 Jan 7; 1(29)153-8
Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1.
Cruz-Orengo L, Dhaka A, Heuermann RJ, Young TJ, Montana MC, Cavanaugh EJ, Kim D, Story GM.
Mol Pain. 2008 Jul 31; (4)30
Visualizing cold spots: TRPM8-expressing sensory neurons and their projections.
Dhaka A, Earley TJ, Watson J, Patapoutian A.
J Neurosci. 2008 Jan 16; 3(28)566-75
TRPM8 is required for cold sensation in mice.
Dhaka A, Murray AN, Mathur J, Earley TJ, Petrus MJ, Patapoutian A.
Neuron. 2007 May 3; 3(54)371-8
Trp ion channels and temperature sensation.
Dhaka A, Viswanath V, Patapoutian A.
Annu Rev Neurosci. 2006; (29)135-61
Samarth RM, Saini MR, Maharwal J, Dhaka A, Kumar A.
Indian J Exp Biol. 2002 Nov; 11(40)1245-9
Extrinsic and intrinsic factors governing cell fate in cortical progenitor cultures.
Irvin DK, Dhaka A, Hicks C, Weinmaster G, Kornblum HI.
Dev Neurosci. 2003 Mar-Aug; 2-4(25)162-72
The RAS effector RIN1 modulates the formation of aversive memories.
Dhaka A, Costa RM, Hu H, Irvin DK, Patel A, Kornblum HI, Silva AJ, O'Dell TJ, Colicelli J.
J Neurosci. 2003 Feb 1; 3(23)748-57
The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.
Wang Y, Waldron RT, Dhaka A, Patel A, Riley MM, Rozengurt E, Colicelli J.
Mol Cell Biol. 2002 Feb; 3(22)916-26
Regulation of the oncogenic activity of BCR-ABL by a tightly bound substrate protein RIN1.
Afar DE, Han L, McLaughlin J, Wong S, Dhaka A, Parmar K, Rosenberg N, Witte ON, Colicelli J.
Immunity. 1997 Jun; 6(6)773-82
Protein binding and signaling properties of RIN1 suggest a unique effector function.
Han L, Wong D, Dhaka A, Afar D, White M, Xie W, Herschman H, Witte O, Colicelli J.
Proc Natl Acad Sci U S A. 1997 May 13; 10(94)4954-9