Research Summary
Our research focuses on the origin and regulation of myogenic stem cells in skeletal muscle. Our long-term goal is to identify means to ameliorate age-related muscle deterioration (sarcopenia) and muscle wasting disorders due to muscular dystrophy. Sarcopenia is characterized by a decline in mass, strength, and endurance of skeletal muscles, and by fat accumulation between and within myofibers. Subtle muscle injuries that occur during routine muscle activity raise a continuous demand for functional myofiber repair throughout life. However, myogenic stem cell performance declines in old age.
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string(16) "1981/08/01 00:00"
}
[1]=>
array(2) {
["pubstatus"]=>
string(7) "medline"
["date"]=>
string(16) "1981/08/01 00:01"
}
[2]=>
array(2) {
["pubstatus"]=>
string(6) "entrez"
["date"]=>
string(16) "1981/08/01 00:00"
}
}
["references"]=>
array(0) {
}
["attributes"]=>
array(0) {
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["pmcrefcount"]=>
int(3)
["fulljournalname"]=>
string(21) "Developmental biology"
["elocationid"]=>
string(0) ""
["doctype"]=>
string(8) "citation"
["srccontriblist"]=>
array(0) {
}
["booktitle"]=>
string(0) ""
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string(0) ""
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string(0) ""
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string(0) ""
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["sortpubdate"]=>
string(16) "1981/08/01 00:00"
["sortfirstauthor"]=>
string(8) "Hille MB"
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}
Publications
The following publications were retrieved from PubMed:
Farewell to Professor David Yaffe - A pillar of the myogenesis field.
Yablonka-Reuveni Z, Stockdale F, Nudel U, Israeli D, Blau HM, Shainberg A, Neuman S, Kessler-Icekson G, Krull EM, Paterson B, Fuchs OS, Greenberg D, Sarig R, Halevy O, Ozawa E, Katcoff DJ.
Eur J Transl Myol. 2020 Sep 30; 3(30)9306