Research Summary
Our research focuses on the origin and regulation of myogenic stem cells in skeletal muscle. Our long-term goal is to identify means to ameliorate age-related muscle deterioration (sarcopenia) and muscle wasting disorders due to muscular dystrophy. Sarcopenia is characterized by a decline in mass, strength, and endurance of skeletal muscles, and by fat accumulation between and within myofibers. Subtle muscle injuries that occur during routine muscle activity raise a continuous demand for functional myofiber repair throughout life. However, myogenic stem cell performance declines in old age.
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array(3) {
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string(3) "pii"
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int(4)
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string(20) "0012-1606(81)90336-5"
}
[2]=>
array(3) {
["idtype"]=>
string(3) "pmc"
["idtypen"]=>
int(8)
["value"]=>
string(10) "PMC4096317"
}
[3]=>
array(3) {
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string(3) "mid"
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int(8)
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string(11) "NIHMS591028"
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array(3) {
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string(3) "doi"
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string(28) "10.1016/0012-1606(81)90336-5"
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[5]=>
array(3) {
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int(8)
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string(7) "6793424"
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array(3) {
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string(3) "eid"
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int(8)
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string(7) "6793424"
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[7]=>
array(3) {
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string(5) "pmcid"
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int(5)
["value"]=>
string(46) "pmc-id: PMC4096317;manuscript-id: NIHMS591028;"
}
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["history"]=>
array(3) {
[0]=>
array(2) {
["pubstatus"]=>
string(6) "pubmed"
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string(16) "1981/08/01 00:00"
}
[1]=>
array(2) {
["pubstatus"]=>
string(7) "medline"
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string(16) "1981/08/01 00:01"
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[2]=>
array(2) {
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string(6) "entrez"
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string(16) "1981/08/01 00:00"
}
}
["references"]=>
array(0) {
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array(0) {
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["pmcrefcount"]=>
int(3)
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string(21) "Developmental biology"
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string(0) ""
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string(8) "citation"
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array(0) {
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string(0) ""
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string(0) ""
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string(0) ""
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string(0) ""
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string(16) "1981/08/01 00:00"
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string(8) "Hille MB"
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}
}
Publications
The following publications were retrieved from PubMed:
