faculty

Zipora Yablonka-Reuveni

reuveni@u.washington.edu

University of Washington, 

Cell Signaling & Cell/Environment Interactions

Developmental Biology, Stem Cells & Aging

Gene Expression, Cell Cycle & Chromosome Biology

Origin and regulation of myogenic stem cells in skeletal muscle

Faculty Contact Information

Building: Health Sciences Building Room: G-503 Box: 357420 Phone: 206-685-2708

Accepting Students For:

Research Summary

Our research focuses on the origin and regulation of myogenic stem cells in skeletal muscle. Our long-term goal is to identify means to ameliorate age-related muscle deterioration (sarcopenia) and muscle wasting disorders due to muscular dystrophy. Sarcopenia is characterized by a decline in mass, strength, and endurance of skeletal muscles, and by fat accumulation between and within myofibers. Subtle muscle injuries that occur during routine muscle activity raise a continuous demand for functional myofiber repair throughout life. However, myogenic stem cell performance declines in old age.