Alex Paredez

Assistant Professor

University of Washington


Cell Signaling & Cell/Environment Interactions

Genetics, Genomics & Evolution

Microbiology, Infection & Immunity

Parasitology and Evolution of the Cytoskeleton

Faculty Contact Information

Building: Hitchcock Hall Room: 407 Box: 351800 Phone: 206-221-9197 http://www.biology.washington.edu/users/aparedez

Research Summary

Giardia lamblia, is an extracellular parasite that uses its cytoskeleton to attach to the host intestine. In addition to being a major parasite, it belongs to a deep branching group of eukaryotes known as the Excavates. Intriguingly, Giardia lacks all canonical actin binding proteins. Still, its actin cytoskeleton performs essential cellular roles and has complex organization that is regulated by a minimalistic Rho GTPase signaling system. We aim to uncover the molecules and mechanisms of cytoskeletal regulation for therapeutic development and to gain evolutionary insight.

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