faculty

Jessica Hamerman

jhamerman@benaroyaresearch.org

Professor

Benaroya Research Institute

Cell Signaling & Cell/Environment Interactions

Microbiology, Infection & Immunity

Regulation of macrophage and dendritic cell development, function, and inflammatory responses

Faculty Contact Information

Building: Benaroya Research Institute Box: x Phone: 206-287-1077 https://www.immunology.washington.edu/faculty/affiliate-faculty/hamerman/

Research Summary

Research in the Hamerman Lab is focused on understanding the process of inflammation and how it is regulated by myeloid cells. We study macrophages, initiators of inflammation, and dendritic cells, initiators of adaptive immunity. We focus on molecular mechanisms by which macrophages and dendritic cells initiate inflammatory and immune responses. Our goal is to understand how these myeloid cells respond during infection and inflammation, and how this promotes clearance of pathogens and susceptibility to inflammatory and autoimmune disease, using both mouse and human systems.

DEI Statement

Each individual is unique and needs different things from their mentor, based on their background. I give individualized mentoring for each lab member to help them meet their goals, meeting each trainee where they are currently and where they want to go in the future. Diversity in the lab strengthens each of us individually and the lab as a whole. I am committed to providing an inclusive lab environment for all trainees.

Training Summary

2019 Mentoring Training, University of Wisconsin Center for Improvement of Mentored Experiences in Research (CIMER)

2020 Culturally Aware Mentoring, University of Wisconsin and NIH National Research Mentoring Network

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Publications

The following publications were retrieved from PubMed:

Signals governing monocyte differentiation during inflammation.

Orozco SL, Canny SP, Hamerman JA.

Curr Opin Immunol. 2021 Dec; (73)16-24

The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity.

Bolouri H, Speake C, Skibinski D, Long SA, Hocking AM, Campbell DJ, Hamerman JA, Malhotra U, Buckner JH, Benaroya Research Institute COVID-19 Research Team..

J Clin Invest. 2021 Feb 1; 3(131)

Endotracheal aspirates contain a limited number of lower respiratory tract immune cells.

Orlov M, Morrell ED, Dmyterko V, Hamerman JA, Wurfel MM, Mikacenic C.

Crit Care. 2021 Jan 6; 1(25)14

Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19.

Rodda LB, Netland J, Shehata L, Pruner KB, Morawski PA, Thouvenel CD, Takehara KK, Eggenberger J, Hemann EA, Waterman HR, Fahning ML, Chen Y, Hale M, Rathe J, Stokes C, Wrenn S, Fiala B, Carter L, Hamerman JA, King NP, Gale M Jr, Campbell DJ, Rawlings DJ, Pepper M.

Cell. 2021 Jan 7; 1(184)169-183.e17

Intravenous nanoparticle vaccination generates stem-like TCF1⁺ neoantigen-specific CD8⁺ T cells.

Baharom F, Ramirez-Valdez RA, Tobin KKS, Yamane H, Dutertre CA, Khalilnezhad A, Reynoso GV, Coble VL, Lynn GM, Mulè MP, Martins AJ, Finnigan JP, Zhang XM, Hamerman JA, Bhardwaj N, Tsang JS, Hickman HD, Ginhoux F, Ishizuka AS, Seder RA.

Nat Immunol. 2021 Jan; 1(22)41-52

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Lab Information

Location: Benaroya Research Institute
https://www.benaroyaresearch.org/what-is-bri/scientists-and-laboratories/scientific-staff/jessica-hamerman