Benaroya Research Institute,
Microbiology, Infection & Immunity
Regulation of macrophage development, function, and inflammatory responses
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Research in the Hamerman Lab is focused on understanding the process of inflammation and how it is regulated by myeloid cells. We study macrophages, initiators of inflammation, and dendritic cells, initiators of adaptive immunity. We focus on molecular mechanisms by which macrophages and dendritic cells initiate inflammatory and immune responses. Our goal is to understand how these myeloid cells respond during infection and inflammation, and how this promotes clearance of pathogens and susceptibility to inflammatory and autoimmune disease.