Karol Bomsztyk

DNA methylation yields epigenetic clues into the diabetic nephropathy of Pima Indians.

Bomsztyk K, Denisenko O, Wang Y.

Kidney Int. 2018 Jun; 6(93)1272-1275

Engineering a multicellular vascular niche to model hematopoietic cell trafficking.

Kotha SS, Hayes BJ, Phong KT, Redd MA, Bomsztyk K, Ramakrishnan A, Torok-Storb B, Zheng Y.

Stem Cell Res Ther. 2018 Mar 23; 1(9)77

Genome-wide co-localization of active EGFR and downstream ERK pathway kinases mirrors mitogen-inducible RNA polymerase 2 genomic occupancy.

Mikula M, Skrzypczak M, Goryca K, Paczkowska K, Ledwon JK, Statkiewicz M, Kulecka M, Grzelak M, Dabrowska M, Kuklinska U, Karczmarski J, Rumienczyk I, Jastrzebski K, Miaczynska M, Ginalski K, Bomsztyk K, Ostrowski J.

Nucleic Acids Res. 2016 Dec 1; 21(44)10150-10164

Regulation of ribosomal RNA expression across the lifespan is fine-tuned by maternal diet before implantation.

Denisenko O, Lucas ES, Sun C, Watkins AJ, Mar D, Bomsztyk K, Fleming TP.

Biochim Biophys Acta. 2016 Jul; 7(1859)906-13

SYSTEM-WIDE MAPPING OF ACTIVATED CIRCUITRY IN EXPERIMENTAL SYSTEMIC INFLAMMATORY RESPONSE SYNDROME.

Gharib SA, Mar D, Bomsztyk K, Denisenko O, Dhanireddy S, Liles WC, Altemeier WA.

Shock. 2016 Feb; 2(45)148-56

Quadruplex formation by both G-rich and C-rich DNA strands of the C9orf72 (GGGGCC)8•(GGCCCC)8 repeat: effect of CpG methylation.

Zamiri B, Mirceta M, Bomsztyk K, Macgregor RB Jr, Pearson CE.

Nucleic Acids Res. 2015 Nov 16; 20(43)10055-64

Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis.

Mikula M, Rubel T, Karczmarski J, Statkiewicz M, Bomsztyk K, Ostrowski J.

Proteome Sci. 2015; (13)23

Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation.

Morris DP, Lei B, Longo LD, Bomsztyk K, Schwinn DA, Michelotti GA.

PLoS One. 2015; 8(10)e0134442

Heterogeneity of epigenetic changes at ischemia/reperfusion- and endotoxin-induced acute kidney injury genes.

Mar D, Gharib SA, Zager RA, Johnson A, Denisenko O, Bomsztyk K.

Kidney Int. 2015 Oct; 4(88)734-44

Experimental acute lung injury induces multi-organ epigenetic modifications in key angiogenic genes implicated in sepsis-associated endothelial dysfunction.

Bomsztyk K, Mar D, An D, Sharifian R, Mikula M, Gharib SA, Altemeier WA, Liles WC, Denisenko O.

Crit Care. 2015 May 11; (19)225

M2 Macrophage Polarization Mediates Anti-inflammatory Effects of Endothelial Nitric Oxide Signaling.

Lee WJ, Tateya S, Cheng AM, Rizzo-DeLeon N, Wang NF, Handa P, Wilson CL, Clowes AW, Sweet IR, Bomsztyk K, Schwartz MW, Kim F.

Diabetes. 2015 Aug; 8(64)2836-46

Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice.

Reddy MA, Sumanth P, Lanting L, Yuan H, Wang M, Mar D, Alpers CE, Bomsztyk K, Natarajan R.

Kidney Int. 2014 Feb; 2(85)362-73

Epigenetic alterations in acute kidney injury.

Bomsztyk K, Denisenko O.

Semin Nephrol. 2013 Jul; 4(33)327-40

Synchronous recruitment of epigenetic modifiers to endotoxin synergistically activated Tnf-α gene in acute kidney injury.

Bomsztyk K, Flanagin S, Mar D, Mikula M, Johnson A, Zager R, Denisenko O.

PLoS One. 2013; 7(8)e70322

Activation of Wnt/β-catenin signaling increases apoptosis in melanoma cells treated with trail.

Zimmerman ZF, Kulikauskas RM, Bomsztyk K, Moon RT, Chien AJ.

PLoS One. 2013; 7(8)e69593

Heterogeneous nuclear ribonucleoprotein (HnRNP) K genome-wide binding survey reveals its role in regulating 3'-end RNA processing and transcription termination at the early growth response 1 (EGR1) gene through XRN2 exonuclease.

Mikula M, Bomsztyk K, Goryca K, Chojnowski K, Ostrowski J.

J Biol Chem. 2013 Aug 23; 34(288)24788-98

Epigenetic changes in renal genes dysregulated in mouse and rat models of type 1 diabetes.

Komers R, Mar D, Denisenko O, Xu B, Oyama TT, Bomsztyk K.

Lab Invest. 2013 May; 5(93)543-52

Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages.

Rubinow KB, Wall VZ, Nelson J, Mar D, Bomsztyk K, Askari B, Lai MA, Smith KD, Han MS, Vivekanandan-Giri A, Pennathur S, Albert CJ, Ford DA, Davis RJ, Bornfeldt KE.

J Biol Chem. 2013 Apr 5; 14(288)9957-70

Chromatin structure of two genomic sites for targeted transgene integration in induced pluripotent stem cells and hematopoietic stem cells.

van Rensburg R, Beyer I, Yao XY, Wang H, Denisenko O, Li ZY, Russell DW, Miller DG, Gregory P, Holmes M, Bomsztyk K, Lieber A.

Gene Ther. 2013 Feb; 2(20)201-14

Microplate-based platform for combined chromatin and DNA methylation immunoprecipitation assays.

Yu J, Feng Q, Ruan Y, Komers R, Kiviat N, Bomsztyk K.

BMC Mol Biol. 2011 Nov 18; (12)49

Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene.

Thomas BJ, Rubio ED, Krumm N, Broin PO, Bomsztyk K, Welcsh P, Greally JM, Golden AA, Krumm A.

Epigenetics Chromatin. 2011 Aug 3; (4)14

Maternal malnutrition and placental insufficiency induce global downregulation of gene expression in fetal kidneys.

Denisenko O, Lin B, Louey S, Thornburg K, Bomsztyk K, Bagby S.

J Dev Orig Health Dis. 2011 Apr; 2(2)124-33

Direct recruitment of ERK cascade components to inducible genes is regulated by heterogeneous nuclear ribonucleoprotein (hnRNP) K.

Mikula M, Bomsztyk K.

J Biol Chem. 2011 Mar 18; 11(286)9763-75

Profiling RNA polymerase II using the fast chromatin immunoprecipitation method.

Nelson J, Denisenko O, Bomsztyk K.

Methods Mol Biol. 2011; (703)219-34

Direct recruitment of insulin receptor and ERK signaling cascade to insulin-inducible gene loci.

Nelson JD, LeBoeuf RC, Bomsztyk K.

Diabetes. 2011 Jan; 1(60)127-37

Poly(ADP-ribose) polymerase-1 (PARP-1) contributes to the barrier function of a vertebrate chromatin insulator.

Aker M, Bomsztyk K, Emery DW.

J Biol Chem. 2010 Nov 26; 48(285)37589-97

Halogenated imidazole derivatives block RNA polymerase II elongation along mitogen inducible genes.

Mikula M, Hanusek K, Paziewska A, Dzwonek A, Rubel T, Bomsztyk K, Ostrowski J.

BMC Mol Biol. 2010 Jan 15; (11)4

The fast chromatin immunoprecipitation method.

Nelson J, Denisenko O, Bomsztyk K.

Methods Mol Biol. 2009; (567)45-57

BRG1 increases transcription of proinflammatory genes in renal ischemia.

Naito M, Zager RA, Bomsztyk K.

J Am Soc Nephrol. 2009 Aug; 8(20)1787-96

High ambient glucose augments angiotensin II-induced proinflammatory gene mRNA expression in human mesangial cells: effects of valsartan and simvastatin.

Naito M, Shenoy A, Aoyama I, Koopmeiners JS, Komers R, Schnaper HW, Bomsztyk K.

Am J Nephrol. 2009; 2(30)99-111

Renal ischemia-induced cholesterol loading: transcription factor recruitment and chromatin remodeling along the HMG CoA reductase gene.

Naito M, Bomsztyk K, Zager RA.

Am J Pathol. 2009 Jan; 1(174)54-62

Growth and development alter susceptibility to acute renal injury.

Zager RA, Johnson AC, Naito M, Lund SR, Kim N, Bomsztyk K.

Kidney Int. 2008 Sep; 5(74)674-8

Endotoxin mediates recruitment of RNA polymerase II to target genes in acute renal failure.

Naito M, Bomsztyk K, Zager RA.

J Am Soc Nephrol. 2008 Jul; 7(19)1321-30

Microplate-based chromatin immunoprecipitation method, Matrix ChIP: a platform to study signaling of complex genomic events.

Flanagin S, Nelson JD, Castner DG, Denisenko O, Bomsztyk K.

Nucleic Acids Res. 2008 Feb; 3(36)e17

Transcription of laminin gamma1 chain gene in rat mesangial cells: constitutive and inducible RNA polymerase II recruitment and chromatin states.

Nelson JD, Flanagin S, Kawata Y, Denisenko O, Bomsztyk K.

Am J Physiol Renal Physiol. 2008 Mar; 3(294)F525-33

Role of chromatin structure in integration of helper-dependent adenoviral vectors containing the beta-globin locus control region.

Sova P, Wang H, Bomsztyk K, Stamatoyannopoulos G, Lieber A.

Hum Gene Ther. 2008 Feb; 2(19)153-66

Epistatic interaction between the K-homology domain protein HEK2 and SIR1 at HMR and telomeres in yeast.

Denisenko O, Bomsztyk K.

J Mol Biol. 2008 Jan 25; 4(375)1178-87

Maleate nephrotoxicity: mechanisms of injury and correlates with ischemic/hypoxic tubular cell death.

Zager RA, Johnson AC, Naito M, Bomsztyk K.

Am J Physiol Renal Physiol. 2008 Jan; 1(294)F187-97

Quantitative model for binary measurements of protein-protein interactions.

Shi YY, Miller GA, Denisenko O, Qian H, Bomsztyk K.

J Comput Biol. 2007 Sep; 7(14)1011-23

Clustering coefficients of protein-protein interaction networks.

Miller GA, Shi YY, Qian H, Bomsztyk K.

Phys Rev E Stat Nonlin Soft Matter Phys. 2007 May; 5 Pt 1(75)051910

Heterogeneous nuclear ribonucleoprotein K contributes to angiotensin II stimulation of vascular endothelial growth factor mRNA translation.

Feliers D, Lee MJ, Ghosh-Choudhury G, Bomsztyk K, Kasinath BS.

Am J Physiol Renal Physiol. 2007 Aug; 2(293)F607-15

Protocol for the fast chromatin immunoprecipitation (ChIP) method.

Nelson JD, Denisenko O, Bomsztyk K.

Nat Protoc. 2006; 1(1)179-85

Free-energy distribution of binary protein-protein binding suggests cross-species interactome differences.

Shi YY, Miller GA, Qian H, Bomsztyk K.

Proc Natl Acad Sci U S A. 2006 Aug 1; 31(103)11527-32

RACK1 binds to Smad3 to modulate transforming growth factor-beta1-stimulated alpha2(I) collagen transcription in renal tubular epithelial cells.

Okano K, Schnaper HW, Bomsztyk K, Hayashida T.

J Biol Chem. 2006 Sep 8; 36(281)26196-204

Heterogeneous nuclear ribonucleoprotein K modulates angiotensinogen gene expression in kidney cells.

Wei CC, Zhang SL, Chen YW, Guo DF, Ingelfinger JR, Bomsztyk K, Chan JS.

J Biol Chem. 2006 Sep 1; 35(281)25344-55

Landscape of the hnRNP K protein-protein interactome.

Mikula M, Dzwonek A, Karczmarski J, Rubel T, Dadlez M, Wyrwicz LS, Bomsztyk K, Ostrowski J.

Proteomics. 2006 Apr; 8(6)2395-406

Casein kinases phosphorylate multiple residues spanning the entire hnRNP K length.

Mikula M, Karczmarski J, Dzwonek A, Rubel T, Hennig E, Dadlez M, Bujnicki JM, Bomsztyk K, Ostrowski J.

Biochim Biophys Acta. 2006 Feb; 2(1764)299-306

Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa.

Klimek-Tomczak K, Mikula M, Dzwonek A, Paziewska A, Karczmarski J, Hennig E, Bujnicki JM, Bragoszewski P, Denisenko O, Bomsztyk K, Ostrowski J.

Br J Cancer. 2006 Feb 27; 4(94)586-92

Fast chromatin immunoprecipitation assay.

Nelson JD, Denisenko O, Sova P, Bomsztyk K.

Nucleic Acids Res. 2006 Jan 5; 1(34)e2

Cooperative binding of the hnRNP K three KH domains to mRNA targets.

Paziewska A, Wyrwicz LS, Bujnicki JM, Bomsztyk K, Ostrowski J.

FEBS Lett. 2004 Nov 5; 1-2(577)134-40

Heterogeneous nuclear ribonucleoprotein K enhances insulin-induced expression of mitochondrial UCP2 protein.

Ostrowski J, Klimek-Tomczak K, Wyrwicz LS, Mikula M, Schullery DS, Bomsztyk K.

J Biol Chem. 2004 Dec 24; 52(279)54599-609

Characterization of hnRNP K protein-RNA interactions.

Klimek-Tomczak K, Wyrwicz LS, Jain S, Bomsztyk K, Ostrowski J.

J Mol Biol. 2004 Sep 24; 4(342)1131-41

hnRNP K: one protein multiple processes.

Bomsztyk K, Denisenko O, Ostrowski J.

Bioessays. 2004 Jun; 6(26)629-38

Nuclear shift of hnRNP K protein in neoplasms and other states of enhanced cell proliferation.

Ostrowski J, Bomsztyk K.

Br J Cancer. 2003 Oct 20; 8(89)1493-501

Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo.

Evans JR, Mitchell SA, Spriggs KA, Ostrowski J, Bomsztyk K, Ostarek D, Willis AE.

Oncogene. 2003 Sep 11; 39(22)8012-20

Transient recruitment of the hnRNP K protein to inducibly transcribed gene loci.

Ostrowski J, Kawata Y, Schullery DS, Denisenko ON, Bomsztyk K.

Nucleic Acids Res. 2003 Jul 15; 14(31)3954-62

c-Src-mediated phosphorylation of hnRNP K drives translational activation of specifically silenced mRNAs.

Ostareck-Lederer A, Ostareck DH, Cans C, Neubauer G, Bomsztyk K, Superti-Furga G, Hentze MW.

Mol Cell Biol. 2002 Jul; 13(22)4535-43

Synergistic activation of the rat laminin gamma1 chain promoter by the gut-enriched Kruppel-like factor (GKLF/KLF4) and Sp1.

Higaki Y, Schullery D, Kawata Y, Shnyreva M, Abrass C, Bomsztyk K.

Nucleic Acids Res. 2002 Jun 1; 11(30)2270-9

bcn-1 Element-dependent activation of the laminin gamma 1 chain gene by the cooperative action of transcription factor E3 (TFE3) and Smad proteins.

Kawata Y, Suzuki H, Higaki Y, Denisenko O, Schullery D, Abrass C, Bomsztyk K.

J Biol Chem. 2002 Mar 29; 13(277)11375-84

Heterogeneous nuclear ribonucleoprotein K protein associates with multiple mitochondrial transcripts within the organelle.

Ostrowski J, Wyrwicz L, Rychlewski L, Bomsztyk K.

J Biol Chem. 2002 Feb 22; 8(277)6303-10

Yeast hnRNP K-like genes are involved in regulation of the telomeric position effect and telomere length.

Denisenko O, Bomsztyk K.

Mol Cell Biol. 2002 Jan; 1(22)286-97

Insulin alters heterogeneous nuclear ribonucleoprotein K protein binding to DNA and RNA.

Ostrowski J, Kawata Y, Schullery DS, Denisenko ON, Higaki Y, Abrass CK, Bomsztyk K.

Proc Natl Acad Sci U S A. 2001 Jul 31; 16(98)9044-9

Treatment of mice with EGF and orthovanadate activates cytoplasmic and nuclear MAPK, p70S6k, and p90rsk in the liver.

Ostrowski J, Woszczyński M, Kowalczyk P, Trzeciak L, Hennig E, Bomsztyk K.

J Hepatol. 2000 Jun; 6(32)965-74

Interaction of two multifunctional proteins. Heterogeneous nuclear ribonucleoprotein K and Y-box-binding protein.

Shnyreva M, Schullery DS, Suzuki H, Higaki Y, Bomsztyk K.

J Biol Chem. 2000 May 19; 20(275)15498-503

Increased activity of MAP, p70S6 and p90rs kinases is associated with AP-1 activation in spontaneous liver tumours, but not in adjacent tissue in mice.

Ostrowski J, Woszczynski M, Kowalczyk P, Wocial T, Hennig E, Trzeciak L, Janik P, Bomsztyk K.

Br J Cancer. 2000 Mar; 5(82)1041-50

Role of tyrosine phosphorylation in the regulation of the interaction of heterogenous nuclear ribonucleoprotein K protein with its protein and RNA partners.

Ostrowski J, Schullery DS, Denisenko ON, Higaki Y, Watts J, Aebersold R, Stempka L, Gschwendt M, Bomsztyk K.

J Biol Chem. 2000 Feb 4; 5(275)3619-28

Regulated interaction of protein kinase Cdelta with the heterogeneous nuclear ribonucleoprotein K protein.

Schullery DS, Ostrowski J, Denisenko ON, Stempka L, Shnyreva M, Suzuki H, Gschwendt M, Bomsztyk K.

J Biol Chem. 1999 May 21; 21(274)15101-9

Increased constitutive activity of mitogen-activated protein kinase and renaturable 85 kDa kinase in human-colorectal cancer.

Ostrowski J, Trzeciak L, Kołodziejski J, Bomsztyk K.

Br J Cancer. 1998 Nov; 10(78)1301-6

Inducible transcriptional activity of bcn-1 element from laminin gamma1-chain gene promoter in renal and nonrenal cells.

Suzuki H, Denisenko ON, Suzuki Y, Schullery DS, Bomsztyk K.

Am J Physiol. 1998 Oct; 4(275)F518-26

Point mutations in the WD40 domain of Eed block its interaction with Ezh2.

Denisenko O, Shnyreva M, Suzuki H, Bomsztyk K.

Mol Cell Biol. 1998 Oct; 10(18)5634-42

Stimulation of p85/RING3 kinase in multiple organs after systemic administration of mitogens into mice.

Ostrowski J, Florio SK, Denis GV, Suzuki H, Bomsztyk K.

Oncogene. 1998 Mar 5; 9(16)1223-7

Cloning of rat laminin gamma 1-chain gene promoter reveals motifs for recognition of multiple transcription factors.

O'Neill BC, Suzuki H, Loomis WP, Denisenko O, Bomsztyk K.

Am J Physiol. 1997 Sep; 3 Pt 2(273)F411-20

The product of the murine homolog of the Drosophila extra sex combs gene displays transcriptional repressor activity.

Denisenko ON, Bomsztyk K.

Mol Cell Biol. 1997 Aug; 8(17)4707-17

Diverse molecular interactions of the hnRNP K protein.

Bomsztyk K, Van Seuningen I, Suzuki H, Denisenko O, Ostrowski J.

FEBS Lett. 1997 Feb 17; 2(403)113-5

Cloning of a new human gene with short consensus repeats using the EST database.

Nangaku M, Shankland SJ, Kurokawa K, Bomsztyk K, Johnson RJ, Couser WG.

Immunogenetics. 1997; 2(46)99-103

Zik1, a transcriptional repressor that interacts with the heterogeneous nuclear ribonucleoprotein particle K protein.

Denisenko ON, O'Neill B, Ostrowski J, Van Seuningen I, Bomsztyk K.

J Biol Chem. 1996 Nov 1; 44(271)27701-6

Activation of a nuclear DNA-binding protein recognized by a transcriptional element, bcn-1, from the laminin B2 chain gene promoter.

Suzuki H, O'Neill BC, Suzuki Y, Denisenko ON, Bomsztyk K.

J Biol Chem. 1996 Aug 2; 31(271)18981-8

Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes.

Valentine MA, Czernik AJ, Rachie N, Hidaka H, Fisher CL, Cambier JC, Bomsztyk K.

J Exp Med. 1995 Dec 1; 6(182)1943-9

The K protein domain that recruits the interleukin 1-responsive K protein kinase lies adjacent to a cluster of c-Src and Vav SH3-binding sites. Implications that K protein acts as a docking platform.

Van Seuningen I, Ostrowski J, Bustelo XR, Sleath PR, Bomsztyk K.

J Biol Chem. 1995 Nov 10; 45(270)26976-85

Description of an IL-1-responsive kinase that phosphorylates the K protein. Enhancement of phosphorylation by selective DNA and RNA motifs.

Van Seuningen I, Ostrowski J, Bomsztyk K.

Biochemistry. 1995 Apr 25; 16(34)5644-50

Diphosphoryl lipid A from Rhodobacter sphaeroides transiently activates NF-kappa B but inhibits lipopolysaccharide induction of kappa light chain and Oct-2 in the B-cell lymphoma line 70Z/3.

Lawrence O, Rachie N, Qureshi N, Bomsztyk K, Sibley CH.

Infect Immun. 1995 Mar; 3(63)1040-6

IL-1 beta increases laminin B2 chain mRNA levels and activates NF-kappa B in rat glomerular epithelial cells.

Richardson CA, Gordon KL, Couser WG, Bomsztyk K.

Am J Physiol. 1995 Feb; 2 Pt 2(268)F273-8

Fibronectin attachment activates the NF-kappa B p50/p65 heterodimer in fibroblasts and smooth muscle cells.

Qwarnström EE, Ostberg CO, Turk GL, Richardson CA, Bomsztyk K.

J Biol Chem. 1994 Dec 9; 49(269)30765-8

Purification, cloning, and expression of a murine phosphoprotein that binds the kappa B motif in vitro identifies it as the homolog of the human heterogeneous nuclear ribonucleoprotein K protein. Description of a novel DNA-dependent phosphorylation process.

Ostrowski J, Van Seuningen I, Seger R, Rauch CT, Sleath PR, McMullen BA, Bomsztyk K.

J Biol Chem. 1994 Jul 1; 26(269)17626-34

Identification of an inducible 85-kDa nuclear protein kinase.

Rachie NA, Seger R, Valentine MA, Ostrowski J, Bomsztyk K.

J Biol Chem. 1993 Oct 15; 29(268)22143-9

Comparison of IL-1 alpha effectiveness in activating murine pre-B and T cell lines.

Iwasaki T, Sims JE, Grabstein K, Dower SK, Rachie N, Bomsztyk K.

Cytokine. 1993 Sep; 5(5)416-26

Purification of DNA-binding proteins using tandem DNA-affinity column.

Ostrowski J, Bomsztyk K.

Nucleic Acids Res. 1993 Feb 25; 4(21)1045-6

Generation of phosphatidic acid and diacylglycerols following ligation of surface immunoglobulin in human B lymphocytes: potential role in PKC activation.

Valentine MA, Bursten SL, Harris WE, Draves KE, Pollok BA, Ostrowski J, Bomsztyk K, Clark EA.

Cell Immunol. 1992 May; 2(141)373-87

Effects of amiloride on distal renal tubule sodium and calcium absorption: dependence on luminal pH.

Mori Y, Machida T, Miyakawa S, Bomsztyk K.

Pharmacol Toxicol. 1992 Mar; 3(70)201-4

Herbimycin A blocks IL-1-induced NF-kappa B DNA-binding activity in lymphoid cell lines.

Iwasaki T, Uehara Y, Graves L, Rachie N, Bomsztyk K.

FEBS Lett. 1992 Feb 24; 2-3(298)240-4

Interleukin-1 rapidly stimulates lysophosphatidate acyltransferase and phosphatidate phosphohydrolase activities in human mesangial cells.

Bursten SL, Harris WE, Bomsztyk K, Lovett D.

J Biol Chem. 1991 Nov 5; 31(266)20732-43

Activation of endothelial-leukocyte adhesion molecule 1 (ELAM-1) gene transcription.

Montgomery KF, Osborn L, Hession C, Tizard R, Goff D, Vassallo C, Tarr PI, Bomsztyk K, Lobb R, Harlan JM.

Proc Natl Acad Sci U S A. 1991 Aug 1; 15(88)6523-7

A serine/threonine kinase activity is closely associated with a 65-kDa phosphoprotein specifically recognized by the kappa B enhancer element.

Ostrowski J, Sims JE, Sibley CH, Valentine MA, Dower SK, Meier KE, Bomsztyk K.

J Biol Chem. 1991 Jul 5; 19(266)12722-33

Evidence that interleukin-1 and phorbol esters activate NF-kappa B by different pathways: role of protein kinase C.

Bomsztyk K, Rooney JW, Iwasaki T, Rachie NA, Dower SK, Sibley CH.

Cell Regul. 1991 Apr; 4(2)329-35

Effects of interleukin-1 and gamma interferon on total intracellular magnesium concentration in a murine lymphoid cell line.

Huynh TT, Bomsztyk K.

Magnes Trace Elem. 1991-1992; 5-6(10)321-6

Weak bases increase surface IgM expression in 70Z/3 B lymphoid cell line without increasing kappa gene expression.

Ostrowski J, Sibley CH, Stepinski J, Stanton TH, Smith LL, Bomsztyk K.

Cell Immunol. 1990 Oct 1; 1(130)11-21

Role of cAMP in interleukin-1-induced kappa light chain gene expression in murine B cell line.

Bomsztyk K, Toivola B, Emery DW, Rooney JW, Dower SK, Rachie NA, Sibley CH.

J Biol Chem. 1990 Jun 5; 16(265)9413-7

Molecular heterogeneity of interleukin-1 receptors.

Dower SK, Sims JE, Stanton TH, Slack J, McMahan CJ, Valentine MA, Bomsztyk K.

Ann N Y Acad Sci. 1990; (594)231-9

Evidence for different interleukin 1 receptors in murine B- and T-cell lines.

Bomsztyk K, Sims JE, Stanton TH, Slack J, McMahan CJ, Valentine MA, Dower SK.

Proc Natl Acad Sci U S A. 1989 Oct; 20(86)8034-8

Properties of interleukin-1 and interferon-gamma receptors in B lymphoid cell line.

Bomsztyk K, Stanton TH, Smith LL, Rachie NA, Dower SK.

J Biol Chem. 1989 Apr 15; 11(264)6052-7

Interaction of signal transduction pathways in mediating acid secretion by rat parietal cells.

Ostrowski J, Bomsztyk K.

Am J Physiol. 1989 Apr; 4 Pt 1(256)C873-9

Interferon-gamma and interleukin-1 alpha induce transient translocation of protein kinase C activity to membranes in a B lymphoid cell line. Evidence for a protein kinase C-independent pathway in lymphokine-induced cytoplasmic alkalinization.

Ostrowski J, Meier KE, Stanton TH, Smith LL, Bomsztyk K.

J Biol Chem. 1988 Sep 25; 27(263)13786-90

Recombinant murine interferon-gamma-induced differentiation of pre-B lymphocytes is associated with Na+/H+ exchange-dependent and -independent cytoplasmic alkalinization.

Smith LL, Stanton TH, Calalb MB, Bomsztyk K.

J Biol Chem. 1988 May 25; 15(263)7359-63

Bicarbonate absorption stimulates active calcium absorption in the rat proximal tubule.

Bomsztyk K, Calalb MB.

J Clin Invest. 1988 May; 5(81)1455-61

A microelectrometric titration method for measurement of total intracellular Cl- concentration.

Bomsztyk K, Calalb MB, Smith L, Stanton TH.

Am J Physiol. 1988 Jan; 1 Pt 1(254)C200-5

Recombinant human interleukin 1-stimulated Na+/H+ exchange is not required for differentiation in pre-B lymphocyte cell line, 70Z/3.

Calalb MB, Stanton TH, Smith L, Cragoe EJ Jr, Bomsztyk K.

J Biol Chem. 1987 Mar 15; 8(262)3680-4

HCO3 accumulation in proximal tubule: roles of carbonic anhydrase, luminal buffers, and pH.

Bomsztyk K, Swenson ER, Calalb MB.

Am J Physiol. 1987 Mar; 3 Pt 2(252)F501-8

A new microelectrode method for simultaneous measurement of pH and PCO2.

Bomsztyk K, Calalb MB.

Am J Physiol. 1986 Nov; 5 Pt 2(251)F933-7

Chloride transport by rat renal proximal tubule: effects of bicarbonate absorption.

Bomsztyk K

Am J Physiol. 1986 Jun; 6 Pt 2(250)F1046-54

Effect of interleukin-1 on intracellular concentration of sodium, calcium, and potassium in 70Z/3 cells.

Stanton TH, Maynard M, Bomsztyk K.

J Biol Chem. 1986 May 5; 13(261)5699-701

Dependence of ion fluxes on fluid transport by rat proximal tubule.

Bomsztyk K, Wright FS.

Am J Physiol. 1986 Apr; 4 Pt 2(250)F680-9

Calcium transport by the proximal tubule.

Wright FS, Bomsztyk K.

Adv Exp Med Biol. 1986; (208)165-70

Effects of luminal fluid anions on calcium transport by proximal tubule.

Bomsztyk K, George JP, Wright FS.

Am J Physiol. 1984 May; 5 Pt 2(246)F600-8