faculty

Matthew Parsek

parsem@uw.edu
Professor

University of Washington

Cell Signaling & Cell/Environment Interactions

Genetics, Genomics & Evolution

Microbiology, Infection & Immunity

Bacterial communities and their relationship to disease.

Faculty Contact Information

Building: F-building SLU Room: 850 Box: Department of Microbiology – Box 357242 University Phone: 206-221-7871

Research Summary

Biofilm formation has been linked to many chronic bacterial infections. Thus, significant research has been directed towards understanding the basic biology behind biofilm formation. Biofilms produce an extracellular matrix that functions, in part, to hold the community together. Pseudomonas aeruginosa represents a paradigm species that we use to study of biofilms in the laboratory.

DEI Statement

My lab fosters a culture of scientific creativity and curiosity. We look to attract the best scientists at all levels of training and give them top-notch mentoring and the freedom to pursue the scientific questions they find most interesting. Everyone is welcome— as my lab is an inclusive workplace, our lab mates are comfortable bringing their authentic selves to work. We feel that the freedom to express who you are is integral to creativity, clear communication, and the scientific process.

Training Summary

Online workshop:
Inclusive teaching and mentoring: A facilitated conversation for educators in the Department of Microbiology

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&query_key=1&WebEnv=MCID_614deba61693f45db122077b&retmode=json
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Publications

The following publications were retrieved from PubMed:

L-Arabinose Transport and Metabolism in Salmonella Influences Biofilm Formation.

Vasicek EM, O'Neal L, Parsek MR, Fitch J, White P, Gunn JS.

Front Cell Infect Microbiol. 2021; (11)698146

The role of Psl in the failure to eradicate Pseudomonas aeruginosa biofilms in children with cystic fibrosis.

Morris AJ, Jackson L, Cw Yau Y, Reichhardt C, Beaudoin T, Uwumarenogie S, Guttman KM, Lynne Howell P, Parsek MR, Hoffman LR, Nguyen D, DiGiandomenico A, Guttman DS, Wozniak DJ, Waters VJ.

NPJ Biofilms Microbiomes. 2021 Aug 4; 1(7)63

Bacterial cyclic diguanylate signaling networks sense temperature.

Almblad H, Randall TE, Liu F, Leblanc K, Groves RA, Kittichotirat W, Winsor GL, Fournier N, Au E, Groizeleau J, Rich JD, Lou Y, Granton E, Jennings LK, Singletary LA, Winstone TML, Good NM, Bumgarner RE, Hynes MF, Singh M, Stietz MS, Brinkman FSL, Kumar A, Brassinga AKC, Parsek MR, Tseng BS, Lewis IA, Yipp BG, MacCallum JL, Harrison JJ.

Nat Commun. 2021 Mar 31; 1(12)1986

Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies.

Jennings LK, Dreifus JE, Reichhardt C, Storek KM, Secor PR, Wozniak DJ, Hisert KB, Parsek MR.

Cell Rep. 2021 Feb 23; 8(34)108782

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