University of Washington,
Biophysical and Structural Biology
Cell Signaling & Cell/Environment Interactions
Discovery and characterization of G protein-coupled receptor macromolecular complexes
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The research interests of the laboratory focus on the study of G-protein coupled receptors (GPCRs). GPCRs comprise ~1% of the entire genome and represent the target for >30% of all commercially available pharmaceutical drugs.
Our currents interests include the study of the adrenergic, sensory and orphan receptors. Using mass spectrometry and biochemical techniques, we are identifying novel protein binding partners for GPCRs.