Cell Signaling & Cell/Environment Interactions
Microbiology, Infection & Immunity
Cancer Immunology and Immunotherapy
Faculty Contact Information
We use genetically engineered mouse models to elucidate the interactions between developing and progressing tumors, and to identify potential molecules and pathways that can be targeted to promote an effective immune response against an established tumor. Many of the derived insights are being advanced via genetic engineering of T cells using synthetic biology and gene editing to create T cells more capable of eradicating tumors. This work is proceeding not only in preclinical mouse models but also in clinical trials in cancer patients with genetically engineered T cells.
My goal as a mentor and lab head is to create an environment where each individual in our group can succeed. As people in the lab come from diverse backgrounds and life experiences, this requires identifying the needs and talents of each member and then both helping them both to maximize and expand their skills and to integrate into the lab environment, with the goals of being both successful in their research efforts and happy and satisfied in their daily experiences with the research community.
University of Washington Department of Immunology DEI discussions and training