faculty

Samuel Miller

millersi@uw.edu
Professor

University of Washington

Microbiology

Microbiology, Infection & Immunity

Faculty Contact Information

Building: Health Sciences Room: K 140 Box: 357710 Phone: 616-511 http://miller-lab.net/MillerLab/

Research Summary

The lab is organized into research groups focusing on the study of:

Salmonellae translocated effectors (which are delivered across the phagosome membrane and recruited to the actin cytoskeleton, nucleus, and phagosome).

The environmental remodeling of the gram-negative bacterial envelop that occurs when bacteria infect host tissues.

Analysis of intestinal microbiome in cystic fibrosis.

Characterizing Genes of Unknown Functions (GUNKs) important for envelope barrier in Acinetobacter bumannii.

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Publications

The following publications were retrieved from PubMed:

Maintenance tobramycin primarily affects untargeted bacteria in the CF sputum microbiome.

Nelson MT, Wolter DJ, Eng A, Weiss EJ, Vo AT, Brittnacher MJ, Hayden HS, Ravishankar S, Bautista G, Ratjen A, Blackledge M, McNamara S, Nay L, Majors C, Miller SI, Borenstein E, Simon RH, LiPuma JJ, Hoffman LR.

Thorax. 2020 Sep; 9(75)780-790

Toxin Glycan Binding: Lectin Keys Unlocking Host and Tissue Specificity.

Petersen E, Miller SI.

Cell Host Microbe. 2020 Jun 10; 6(27)851-853

Fecal dysbiosis in infants with cystic fibrosis is associated with early linear growth failure.

Hayden HS, Eng A, Pope CE, Brittnacher MJ, Vo AT, Weiss EJ, Hager KR, Martin BD, Leung DH, Heltshe SL, Borenstein E, Miller SI, Hoffman LR.

Nat Med. 2020 Feb; 2(26)215-221

SapTrap Assembly of Caenorhabditis elegans MosSCI Transgene Vectors.

Fan X, De Henau S, Feinstein J, Miller SI, Han B, Frøkjær-Jensen C, Griffin EE.

G3 (Bethesda). 2020 Feb 6; 2(10)635-644

Xenophagy: Pathogen-Containing Vacuoles Are Hard to Digest.

Chaudhary A, Miller SI.

Curr Biol. 2019 Oct 21; 20(29)R1086-R1088