faculty

Peter Nelson

pnelson@fhcrc.org
Member

Fred Hutch

Human Biology

Cancer Biology

Developmental Biology, Stem Cells & Aging

Gene Expression, Cell Cycle & Chromosome Biology

Genetics and Genomics of Cancer

Faculty Contact Information

Building: Thomas Room: D4-109 Box: D4-100 Phone: 206-667-3377

Research Summary

We study several inter-related aspects of cancer biology. We seek to identify and understand the role of key somatic genomic alterations that drive cancer development, metastasis (with organ tropism), and therapy resistance. A second area of focus involves determining influences of the tumor microenvironment on cancer cell behavior. A third area of focus centers on determining the roles of hormones and nuclear hormone receptors as lineage oncogenes, with a particular emphasis on cancer of the prostate, the most common cancer affecting men.

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["name"]=> string(8) "Lakely B" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [11]=> array(3) { ["name"]=> string(9) "Higano CS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [12]=> array(3) { ["name"]=> string(12) "Montgomery B" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [13]=> array(3) { ["name"]=> string(9) "Roudier M" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [14]=> array(3) { ["name"]=> string(8) "Lange PH" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [15]=> array(3) { ["name"]=> string(9) "Nelson PS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [16]=> array(3) { ["name"]=> string(11) "Vessella RL" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [17]=> array(3) { ["name"]=> string(11) "Morrissey C" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(11) "Morrissey C" ["title"]=> string(145) "SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer." ["sorttitle"]=> string(144) "srrm4 expression an