Peter Nelson
pnelson@fhcrc.orgFred Hutch,
Cancer Biology
Developmental Biology, Stem Cells & Aging
Gene Expression, Cell Cycle & Chromosome Biology
Genetics and Genomics of Cancer
Faculty Contact Information
Lab Information
Accepting Students For:
Publications
The following publications were retrieved from PubMed:
ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer.
Cato L, de Tribolet-Hardy J, Lee I, Rottenberg JT, Coleman I, Melchers D, Houtman R, Xiao T, Li W, Uo T, Sun S, Kuznik NC, Göppert B, Ozgun F, van Royen ME, Houtsmuller AB, Vadhi R, Rao PK, Li L, Balk SP, Den RB, Trock BJ, Karnes RJ, Jenkins RB, Klein EA, Davicioni E, Gruhl FJ, Long HW, Liu XS, Cato ACB, Lack NA, Nelson PS, Plymate SR, Groner AC, Brown M.
Cancer Cell. 2019 Feb 12;
EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis.
Zhao Y, Ding L, Wang D, Ye Z, He Y, Ma L, Zhu R, Pan Y, Wu Q, Pang K, Hou X, Weroha SJ, Han C, Coleman R, Coleman I, Karnes RJ, Zhang J, Nelson PS, Wang L, Huang H.
EMBO J. 2019 Feb 5;
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy.
Carlson P, Dasgupta A, Grzelak CA, Kim J, Barrett A, Coleman IM, Shor RE, Goddard ET, Dai J, Schweitzer EM, Lim AR, Crist SB, Cheresh DA, Nelson PS, Hansen KC, Ghajar CM.
Nat Cell Biol. 2019 Feb; 2(21)238-250
Newcomb LF, Zheng Y, Faino AV, Bianchi-Frias D, Cooperberg MR, Brown MD, Brooks JD, Dash A, Fabrizio MD, Gleave ME, Liss M, Morgan TM, Thompson IM, Wagner AA, Carroll PR, Nelson PS, Lin DW.
Prostate Cancer Prostatic Dis. 2019 Jan 21;
Rotinen M, You S, Yang J, Coetzee SG, Reis-Sobreiro M, Huang WC, Huang F, Pan X, Yáñez A, Hazelett DJ, Chu CY, Steadman K, Morrissey CM, Nelson PS, Corey E, Chung LWK, Freedland SJ, Di Vizio D, Garraway IP, Murali R, Knudsen BS, Freeman MR.
Nat Med. 2018 Dec; 12(24)1887-1898
Rodrigues DN, Rescigno P, Liu D, Yuan W, Carreira S, Lambros MB, Seed G, Mateo J, Riisnaes R, Mullane S, Margolis C, Miao D, Miranda S, Dolling D, Clarke M, Bertan C, Crespo M, Boysen G, Ferreira A, Sharp A, Figueiredo I, Keliher D, Aldubayan S, Burke KP, Sumanasuriya S, Fontes MS, Bianchini D, Zafeiriou Z, Mendes LST, Mouw K, Schweizer MT, Pritchard CC, Salipante S, Taplin ME, Beltran H, Rubin MA, Cieslik M, Robinson D, Heath E, Schultz N, Armenia J, Abida W, Scher H, Lord C, D'Andrea A, Sawyers CL, Chinnaiyan AM, Alimonti A, Nelson PS, Drake CG, Van Allen EM, de Bono JS.
J Clin Invest. 2018 Nov 1; 11(128)5185
Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer.
Sharp A, Coleman I, Yuan W, Sprenger C, Dolling D, Rodrigues DN, Russo JW, Figueiredo I, Bertan C, Seed G, Riisnaes R, Uo T, Neeb A, Welti J, Morrissey C, Carreira S, Luo J, Nelson PS, Balk SP, True LD, de Bono JS, Plymate SR.
J Clin Invest. 2019 Jan 2; 1(129)192-208
Russo JW, Gao C, Bhasin SS, Voznesensky OS, Calagua C, Arai S, Nelson PS, Montgomery B, Mostaghel EA, Corey E, Taplin ME, Ye H, Bhasin M, Balk SP.
Cancer Res. 2018 Nov 15; 22(78)6354-6362
Bianchi-Frias D, Damodarasamy M, Hernandez SA, Gil da Costa RM, Vakar-Lopez F, Coleman IM, Reed MJ, Nelson PS.
Mol Cancer Res. 2019 Jan; 1(17)321-331
Mostaghel EA, Zhang A, Hernandez S, Marck BT, Zhang X, Tamae D, Biehl HE, Tretiakova M, Bartlett J, Burns J, Dumpit R, Ang L, Matsumoto AM, Penning TM, Balk SP, Morrissey C, Corey E, True LD, Nelson PS.
Clin Cancer Res. 2019 Jan 1; 1(25)426-439
Nava Rodrigues D, Rescigno P, Liu D, Yuan W, Carreira S, Lambros MB, Seed G, Mateo J, Riisnaes R, Mullane S, Margolis C, Miao D, Miranda S, Dolling D, Clarke M, Bertan C, Crespo M, Boysen G, Ferreira A, Sharp A, Figueiredo I, Keliher D, Aldubayan S, Burke KP, Sumanasuriya S, Fontes MS, Bianchini D, Zafeiriou Z, Teixeira Mendes LS, Mouw K, Schweizer MT, Pritchard CC, Salipante S, Taplin ME, Beltran H, Rubin MA, Cieslik M, Robinson D, Heath E, Schultz N, Armenia J, Abida W, Scher H, Lord C, D'Andrea A, Sawyers CL, Chinnaiyan AM, Alimonti A, Nelson PS, Drake CG, Van Allen EM, de Bono JS.
J Clin Invest. 2018 Oct 1; 10(128)4441-4453
Schweizer MT, Haugk K, McKiernan JS, Gulati R, Cheng HH, Maes JL, Dumpit RF, Nelson PS, Montgomery B, McCune JS, Plymate SR, Yu EY.
PLoS One. 2018; 8(13)e0202709
Kearns JT, Faino AV, Schenk JM, Newcomb LF, Brooks JD, Carroll PR, Dash A, Ellis WJ, Fabrizio M, Gleave ME, Morgan TM, Nelson PS, Thompson IM, Wagner A, Zheng Y, Lin DW.
J Urol. 2019 Jan; 1(201)106-111
Mamouni K, Zhang S, Li X, Chen Y, Yang Y, Kim J, Bartlett MG, Coleman IM, Nelson PS, Kucuk O, Wu D.
Neoplasia. 2018 Aug; 8(20)789-799
Sowalsky AG, Ye H, Bhasin M, Van Allen EM, Loda M, Lis RT, Montaser-Kouhsari L, Calagua C, Ma F, Russo JW, Schaefer RJ, Voznesensky OS, Zhang Z, Bubley GJ, Montgomery B, Mostaghel EA, Nelson PS, Taplin ME, Balk SP.
Cancer Res. 2018 Aug 15; 16(78)4716-4730
Viswanathan SR, Ha G, Hoff AM, Wala JA, Carrot-Zhang J, Whelan CW, Haradhvala NJ, Freeman SS, Reed SC, Rhoades J, Polak P, Cipicchio M, Wankowicz SA, Wong A, Kamath T, Zhang Z, Gydush GJ, Rotem D, PCF/SU2C International Prostate Cancer Dream Team., Love JC, Getz G, Gabriel S, Zhang CZ, Dehm SM, Nelson PS, Van Allen EM, Choudhury AD, Adalsteinsson VA, Beroukhim R, Taplin ME, Meyerson M.
Cell. 2018 Jul 12; 2(174)433-447.e19
Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer.
Wu YM, Cieślik M, Lonigro RJ, Vats P, Reimers MA, Cao X, Ning Y, Wang L, Kunju LP, de Sarkar N, Heath EI, Chou J, Feng FY, Nelson PS, de Bono JS, Zou W, Montgomery B, Alva A, PCF/SU2C International Prostate Cancer Dream Team., Robinson DR, Chinnaiyan AM.
Cell. 2018 Jun 14; 7(173)1770-1782.e14
Schweizer MT, Haugk K, McKiernan JS, Gulati R, Cheng HH, Maes JL, Dumpit RF, Nelson PS, Montgomery B, McCune JS, Plymate SR, Yu EY.
PLoS One. 2018; 6(13)e0198389
Microsatellite instability in prostate cancer by PCR or next-generation sequencing.
Hempelmann JA, Lockwood CM, Konnick EQ, Schweizer MT, Antonarakis ES, Lotan TL, Montgomery B, Nelson PS, Klemfuss N, Salipante SJ, Pritchard CC.
J Immunother Cancer. 2018 Apr 17; 1(6)29
The long tail of oncogenic drivers in prostate cancer.
Armenia J, Wankowicz SAM, Liu D, Gao J, Kundra R, Reznik E, Chatila WK, Chakravarty D, Han GC, Coleman I, Montgomery B, Pritchard C, Morrissey C, Barbieri CE, Beltran H, Sboner A, Zafeiriou Z, Miranda S, Bielski CM, Penson AV, Tolonen C, Huang FW, Robinson D, Wu YM, Lonigro R, Garraway LA, Demichelis F, Kantoff PW, Taplin ME, Abida W, Taylor BS, Scher HI, Nelson PS, de Bono JS, Rubin MA, Sawyers CL, Chinnaiyan AM, PCF/SU2C International Prostate Cancer Dream Team., Schultz N, Van Allen EM, PCF/SU2C International Prostate Cancer Dream Team..
Nat Genet. 2018 May; 5(50)645-651
Belyaeva OV, Wu L, Shmarakov I, Nelson PS, Kedishvili NY.
J Biol Chem. 2018 May 4; 18(293)6996-7007
Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer.
Sahoo D, Wei W, Auman H, Hurtado-Coll A, Carroll PR, Fazli L, Gleave ME, Lin DW, Nelson PS, Simko J, Thompson IM, Leach RJ, Troyer DA, True LD, McKenney JK, Feng Z, Brooks JD.
Oncotarget. 2018 Jan 19; 5(9)6550-6561
Cooperberg MR, Brooks JD, Faino AV, Newcomb LF, Kearns JT, Carroll PR, Dash A, Etzioni R, Fabrizio MD, Gleave ME, Morgan TM, Nelson PS, Thompson IM, Wagner AA, Lin DW, Zheng Y.
Eur Urol. 2018 Aug; 2(74)211-217
Kearns JT, Faino AV, Newcomb LF, Brooks JD, Carroll PR, Dash A, Ellis WJ, Fabrizio M, Gleave ME, Morgan TM, Nelson PS, Thompson IM, Wagner AA, Zheng Y, Lin DW.
Eur Urol. 2018 May; 5(73)706-712
Mateo J, Cheng HH, Beltran H, Dolling D, Xu W, Pritchard CC, Mossop H, Rescigno P, Perez-Lopez R, Sailer V, Kolinsky M, Balasopoulou A, Bertan C, Nanus DM, Tagawa ST, Thorne H, Montgomery B, Carreira S, Sandhu S, Rubin MA, Nelson PS, de Bono JS.
Eur Urol. 2018 May; 5(73)687-693
Chalfin HJ, Glavaris SA, Malihi PD, Sperger JM, Gorin MA, Lu C, Goodwin CR, Chen Y, Caruso EA, Dumpit R, Kuhn P, Lang JM, Nelson PS, Luo J, Pienta KJ.
J Urol. 2018 Jun; 6(199)1494-1501
McKay RR, Montgomery B, Xie W, Zhang Z, Bubley GJ, Lin DW, Preston MA, Trinh QD, Chang P, Wagner AA, Mostaghel EA, Kantoff PW, Nelson PS, Kibel AS, Taplin ME.
Prostate Cancer Prostatic Dis. 2018 Sep; 3(21)364-372
Mohammad OS, Nyquist MD, Schweizer MT, Balk SP, Corey E, Plymate S, Nelson PS, Mostaghel EA.
Cancers (Basel). 2017 Dec 6; 12(9)
Geybels MS, Fang M, Wright JL, Qu X, Bibikova M, Klotzle B, Fan JB, Feng Z, Ostrander EA, Nelson PS, Stanford JL.
Oncotarget. 2017 Oct 13; 48(8)84338-84348
Armstrong AJ, Antonarakis ES, Taplin ME, Kelly WK, Beltran H, Fizazi K, Dahut WL, Shore N, Slovin S, George D, Carducci MA, Corn P, Danila D, Dreicer R, Heath E, Rathkopf D, Liu G, Nanus D, Stein M, Smith MR, Sternberg C, Wilding G, Nelson PS, Halabi S, Kantoff P, Clarke NW, Evans CP, Heidenreich A, Mottet N, Gleave M, Morris MJ, Scher HI.
Ann Oncol. 2018 Jan 1; 1(29)23-25
Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling.
Bluemn EG, Coleman IM, Lucas JM, Coleman RT, Hernandez-Lopez S, Tharakan R, Bianchi-Frias D, Dumpit RF, Kaipainen A, Corella AN, Yang YC, Nyquist MD, Mostaghel E, Hsieh AC, Zhang X, Corey E, Brown LG, Nguyen HM, Pienta K, Ittmann M, Schweizer M, True LD, Wise D, Rennie PS, Vessella RL, Morrissey C, Nelson PS.
Cancer Cell. 2017 Oct 9; 4(32)474-489.e6
Zhu Y, Sharp A, Anderson CM, Silberstein JL, Taylor M, Lu C, Zhao P, De Marzo AM, Antonarakis ES, Wang M, Wu X, Luo Y, Su N, Nava Rodrigues D, Figueiredo I, Welti J, Park E, Ma XJ, Coleman I, Morrissey C, Plymate SR, Nelson PS, de Bono JS, Luo J.
Eur Urol. 2018 May; 5(73)727-735
Prostate Cancer Screening in a New Era of Genetics.
Cheng HH, Pritchard CC, Montgomery B, Lin DW, Nelson PS.
Clin Genitourin Cancer. 2017 Dec; 6(15)625-628
Sinha S, Nelson PS.
Cancer Discov. 2017 Jul; 7(7)673-674
ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis.
Bose R, Karthaus WR, Armenia J, Abida W, Iaquinta PJ, Zhang Z, Wongvipat J, Wasmuth EV, Shah N, Sullivan PS, Doran MG, Wang P, Patruno A, Zhao Y, International SU2C/PCF Prostate Cancer Dream Team., Zheng D, Schultz N, Sawyers CL.
Nature. 2017 Jun 29; 7660(546)671-675
Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer.
Urbanucci A, Barfeld SJ, Kytölä V, Itkonen HM, Coleman IM, Vodák D, Sjöblom L, Sheng X, Tolonen T, Minner S, Burdelski C, Kivinummi KK, Kohvakka A, Kregel S, Takhar M, Alshalalfa M, Davicioni E, Erho N, Lloyd P, Karnes RJ, Ross AE, Schaeffer EM, Vander Griend DJ, Knapp S, Corey E, Feng FY, Nelson PS, Saatcioglu F, Knudsen KE, Tammela TLJ, Sauter G, Schlomm T, Nykter M, Visakorpi T, Mills IG.
Cell Rep. 2017 Jun 6; 10(19)2045-2059
Levesque C, Nelson PS.
Cold Spring Harb Perspect Med. 2018 Aug 1; 8(8)
Exploiting AR-Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155.
Nyquist MD, Corella A, Burns J, Coleman I, Gao S, Tharakan R, Riggan L, Cai C, Corey E, Nelson PS, Mostaghel EA.
Mol Cancer Res. 2017 May; 5(15)521-531
Mostaghel EA, Cho E, Zhang A, Alyamani M, Kaipainen A, Green S, Marck BT, Sharifi N, Wright JL, Gulati R, True LD, Loda M, Matsumoto AM, Tamae D, Penning TN, Balk SP, Kantoff PW, Nelson PS, Taplin ME, Montgomery RB.
Clin Cancer Res. 2017 Aug 15; 16(23)4592-4601
DNA Damage Induces a Secretory Program in the Quiescent TME that Fosters Adverse Cancer Phenotypes.
Gomez-Sarosi L, Sun Y, Coleman I, Bianchi-Frias D, Nelson PS.
Mol Cancer Res. 2017 Jul; 7(15)842-851
Anti-Depressant Therapy Brightens the Outlook for Prostate Cancer Bone Metastases.
Nyquist MD, Nelson PS.
Cancer Cell. 2017 Mar 13; 3(31)303-305
Nguyen HM, Vessella RL, Morrissey C, Brown LG, Coleman IM, Higano CS, Mostaghel EA, Zhang X, True LD, Lam HM, Roudier M, Lange PH, Nelson PS, Corey E.
Prostate. 2017 May; 6(77)654-671
Neoadjuvant Enzalutamide Prior to Prostatectomy.
Montgomery B, Tretiakova MS, Joshua AM, Gleave ME, Fleshner N, Bubley GJ, Mostaghel EA, Chi KN, Lin DW, Sanda M, Novotny W, Wu K, Kantoff PW, Marck BT, Plymate S, Balk SP, Nelson PS, Matsumoto AM, Lis RT, Kibel A, Haas GP, Krivoshik A, Hannah A, Taplin ME.
Clin Cancer Res. 2017 May 1; 9(23)2169-2176
Rubicz R, Zhao S, Wright JL, Coleman I, Grasso C, Geybels MS, Leonardson A, Kolb S, April C, Bibikova M, Troyer D, Lance R, Lin DW, Ostrander EA, Nelson PS, Fan JB, Feng Z, Stanford JL.
Mol Oncol. 2017 Feb; 2(11)140-150
Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors.
Feng S, Shao L, Castro P, Coleman I, Nelson PS, Smith PD, Davies BR, Ittmann M.
Oncotarget. 2017 Jan 24; 4(8)6179-6192
Lam HM, McMullin R, Nguyen HM, Coleman I, Gormley M, Gulati R, Brown LG, Holt SK, Li W, Ricci DS, Verstraeten K, Thomas S, Mostaghel EA, Nelson PS, Vessella RL, Corey E.
Clin Cancer Res. 2017 May 1; 9(23)2301-2312
A proteolytic modification of AIM promotes its renal excretion.
Yamazaki T, Sugisawa R, Hiramoto E, Takai R, Matsumoto A, Senda Y, Nakashima K, Nelson PS, Lucas JM, Morgan A, Li Z, Yamamura KI, Arai S, Miyazaki T.
Sci Rep. 2016 Dec 8; (6)38762
Henzler C, Li Y, Yang R, McBride T, Ho Y, Sprenger C, Liu G, Coleman I, Lakely B, Li R, Ma S, Landman SR, Kumar V, Hwang TH, Raj GV, Higano CS, Morrissey C, Nelson PS, Plymate SR, Dehm SM.
Nat Commun. 2016 Nov 29; (7)13668
Lin DW, Newcomb LF, Brown MD, Sjoberg DD, Dong Y, Brooks JD, Carroll PR, Cooperberg M, Dash A, Ellis WJ, Fabrizio M, Gleave ME, Morgan TM, Nelson PS, Thompson IM, Wagner AA, Zheng Y, Canary Prostate Active Surveillance Study Investigators..
Eur Urol. 2017 Sep; 3(72)448-454
Eminaga O, Wei W, Hawley SJ, Auman H, Newcomb LF, Simko J, Hurtado-Coll A, Troyer DA, Carroll PR, Gleave ME, Lin DW, Nelson PS, Thompson IM, True LD, McKenney JK, Feng Z, Fazli L, Brooks JD.
PLoS One. 2016; 11(11)e0165236
Macleod LC, Ellis WJ, Newcomb LF, Zheng Y, Brooks JD, Carroll PR, Gleave ME, Lance RS, Nelson PS, Thompson IM Jr, Wagner AA, Wei JT, Lin DW.
J Urol. 2017 Apr; 4(197)1026-1033
DNA-Repair Gene Mutations in Metastatic Prostate Cancer.
Pritchard CC, Offit K, Nelson PS.
N Engl J Med. 2016 Nov 3; 18(375)1804-5
DNA Repair in Prostate Cancer: Biology and Clinical Implications.
Mateo J, Boysen G, Barbieri CE, Bryant HE, Castro E, Nelson PS, Olmos D, Pritchard CC, Rubin MA, de Bono JS.
Eur Urol. 2017 Mar; 3(71)417-425
Mismatch repair deficiency may be common in ductal adenocarcinoma of the prostate.
Schweizer MT, Cheng HH, Tretiakova MS, Vakar-Lopez F, Klemfuss N, Konnick EQ, Mostaghel EA, Nelson PS, Yu EY, Montgomery B, True LD, Pritchard CC.
Oncotarget. 2016 Dec 13; 50(7)82504-82510
McKenney JK, Wei W, Hawley S, Auman H, Newcomb LF, Boyer HD, Fazli L, Simko J, Hurtado-Coll A, Troyer DA, Tretiakova MS, Vakar-Lopez F, Carroll PR, Cooperberg MR, Gleave ME, Lance RS, Lin DW, Nelson PS, Thompson IM, True LD, Feng Z, Brooks JD.
Am J Surg Pathol. 2016 Nov; 11(40)1439-1456
Gulati R, Cheng HH, Lange PH, Nelson PS, Etzioni R.
Cancer Epidemiol Biomarkers Prev. 2017 Feb; 2(26)222-227
Uo T, Dvinge H, Sprenger CC, Bradley RK, Nelson PS, Plymate SR.
Oncogene. 2017 Mar; 10(36)1440-1450
Mismatch repair enzyme expression in primary and castrate resistant prostate cancer.
Nghiem B, Zhang X, Lam HM, True LD, Coleman I, Higano CS, Nelson PS, Pritchard CC, Morrissey C.
Asian J Urol. 2016 Oct; 4(3)223-228
Epigenetic signature of Gleason score and prostate cancer recurrence after radical prostatectomy.
Geybels MS, Wright JL, Bibikova M, Klotzle B, Fan JB, Zhao S, Feng Z, Ostrander EA, Lin DW, Nelson PS, Stanford JL.
Clin Epigenetics. 2016; (8)97
Lotan TL, Wei W, Morais CL, Hawley ST, Fazli L, Hurtado-Coll A, Troyer D, McKenney JK, Simko J, Carroll PR, Gleave M, Lance R, Lin DW, Nelson PS, Thompson IM, True LD, Feng Z, Brooks JD.
Eur Urol Focus. 2016 Jun; 2(2)180-188
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
Pritchard CC, Mateo J, Walsh MF, De Sarkar N, Abida W, Beltran H, Garofalo A, Gulati R, Carreira S, Eeles R, Elemento O, Rubin MA, Robinson D, Lonigro R, Hussain M, Chinnaiyan A, Vinson J, Filipenko J, Garraway L, Taplin ME, AlDubayan S, Han GC, Beightol M, Morrissey C, Nghiem B, Cheng HH, Montgomery B, Walsh T, Casadei S, Berger M, Zhang L, Zehir A, Vijai J, Scher HI, Sawyers C, Schultz N, Kantoff PW, Solit D, Robson M, Van Allen EM, Offit K, de Bono J, Nelson PS.
N Engl J Med. 2016 Aug 4; 5(375)443-53
Liss MA, Schenk JM, Faino AV, Newcomb LF, Boyer H, Brooks JD, Carroll PR, Dash A, Fabrizio MD, Gleave ME, Nelson PS, Neuhouser ML, Wei JT, Zheng Y, Wright JL, Lin DW, Thompson IM.
Prostate Cancer Prostatic Dis. 2016 Dec; 4(19)390-394
Expression of STAT3 in Prostate Cancer Metastases.
Don-Doncow N, Marginean F, Coleman I, Nelson PS, Ehrnström R, Krzyzanowska A, Morrissey C, Hellsten R, Bjartell A.
Eur Urol. 2017 Mar; 3(71)313-316
Brooks JD, Wei W, Pollack JR, West RB, Shin JH, Sunwoo JB, Hawley SJ, Auman H, Newcomb LF, Simko J, Hurtado-Coll A, Troyer DA, Carroll PR, Gleave ME, Lin DW, Nelson PS, Thompson IM, True LD, McKenney JK, Feng Z, Fazli L.
Prostate. 2016 Nov; 15(76)1409-19
Cheng HH, Klemfuss N, Montgomery B, Higano CS, Schweizer MT, Mostaghel EA, McFerrin LG, Yu EY, Nelson PS, Pritchard CC.
Prostate. 2016 Oct; 14(76)1303-11
Schweizer MT, Gulati R, Mostaghel EA, Nelson PS, Montgomery RB, Yu EY, Cheng HH.
Med Oncol. 2016 Jul; 7(33)77
Lotan TL, Wei W, Ludkovski O, Morais CL, Guedes LB, Jamaspishvili T, Lopez K, Hawley ST, Feng Z, Fazli L, Hurtado-Coll A, McKenney JK, Simko J, Carroll PR, Gleave M, Lin DW, Nelson PS, Thompson IM, True LD, Brooks JD, Lance R, Troyer D, Squire JA.
Mod Pathol. 2016 Aug; 8(29)904-14
Van Allen EM, Robinson D, Morrissey C, Pritchard C, Imamovic A, Carter S, Rosenberg M, McKenna A, Wu YM, Cao X, Chinnaiyan A, Garraway L, Nelson PS.
Oncotarget. 2016 Aug 16; 33(7)52888-52899
Gillessen S, Omlin A, Attard G, de Bono JS, Efstathiou E, Fizazi K, Halabi S, Nelson PS, Sartor O, Smith MR, Soule HR, Akaza H, Beer TM, Beltran H, Chinnaiyan AM, Daugaard G, Davis ID, De Santis M, Drake CG, Eeles RA, Fanti S, Gleave ME, Heidenreich A, Hussain M, James ND, Lecouvet FE, Logothetis CJ, Mastris K, Nilsson S, Oh WK, Olmos D, Padhani AR, Parker C, Rubin MA, Schalken JA, Scher HI, Sella A, Shore ND, Small EJ, Sternberg CN, Suzuki H, Sweeney CJ, Tannock IF, Tombal B.
Ann Oncol. 2016 May 2;
Tretiakova MS, Wei W, Boyer HD, Newcomb LF, Hawley S, Auman H, Vakar-Lopez F, McKenney JK, Fazli L, Simko J, Troyer DA, Hurtado-Coll A, Thompson IM Jr, Carroll PR, Ellis WJ, Gleave ME, Nelson PS, Lin DW, True LD, Feng Z, Brooks JD.
Prostate Cancer Prostatic Dis. 2016 Sep; 3(19)264-70
Roudier MP, Winters BR, Coleman I, Lam HM, Zhang X, Coleman R, Chéry L, True LD, Higano CS, Montgomery B, Lange PH, Snyder LA, Srivastava S, Corey E, Vessella RL, Nelson PS, Üren A, Morrissey C.
Prostate. 2016 Jun; 9(76)810-22
ErbB2 Signaling Increases Androgen Receptor Expression in Abiraterone-Resistant Prostate Cancer.
Gao S, Ye H, Gerrin S, Wang H, Sharma A, Chen S, Patnaik A, Sowalsky AG, Voznesensky O, Han W, Yu Z, Mostaghel EA, Nelson PS, Taplin ME, Balk SP, Cai C.
Clin Cancer Res. 2016 Jul 15; 14(22)3672-82
Kumar A, Coleman I, Morrissey C, Zhang X, True LD, Gulati R, Etzioni R, Bolouri H, Montgomery B, White T, Lucas JM, Brown LG, Dumpit RF, DeSarkar N, Higano C, Yu EY, Coleman R, Schultz N, Fang M, Lange PH, Shendure J, Vessella RL, Nelson PS.
Nat Med. 2016 Apr; 4(22)369-78
Scher HI, Morris MJ, Stadler WM, Higano C, Basch E, Fizazi K, Antonarakis ES, Beer TM, Carducci MA, Chi KN, Corn PG, de Bono JS, Dreicer R, George DJ, Heath EI, Hussain M, Kelly WK, Liu G, Logothetis C, Nanus D, Stein MN, Rathkopf DE, Slovin SF, Ryan CJ, Sartor O, Small EJ, Smith MR, Sternberg CN, Taplin ME, Wilding G, Nelson PS, Schwartz LH, Halabi S, Kantoff PW, Armstrong AJ, Prostate Cancer Clinical Trials Working Group 3..
J Clin Oncol. 2016 Apr 20; 12(34)1402-18
Valta MP, Zhao H, Saar M, Tuomela J, Nolley R, Linxweiler J, Sandholm J, Lehtimäki J, Härkönen P, Coleman I, Nelson PS, Corey E, Peehl DM.
Clin Exp Metastasis. 2016 Apr; 4(33)325-37
Bianchi-Frias D, Basom R, Delrow JJ, Coleman IM, Dakhova O, Qu X, Fang M, Franco OE, Ericson NG, Bielas JH, Hayward SW, True L, Morrissey C, Brown L, Bhowmick NA, Rowley D, Ittmann M, Nelson PS.
Mol Cancer Res. 2016 Apr; 4(14)374-84
Qu X, Jeldres C, Glaskova L, Friedman C, Schroeder S, Nelson PS, Porter C, Fang M.
J Mol Diagn. 2016 Mar; 2(18)215-24
Cheng HH, Pritchard CC, Boyd T, Nelson PS, Montgomery B.
Eur Urol. 2016 Jun; 6(69)992-5
Haider M, Zhang X, Coleman I, Ericson N, True LD, Lam HM, Brown LG, Ketchanji M, Nghiem B, Lakely B, Coleman R, Montgomery B, Lange PH, Roudier M, Higano CS, Bielas JH, Nelson PS, Vessella RL, Morrissey C.
Clin Exp Metastasis. 2016 Mar; 3(33)239-48
Ruscetti M, Dadashian EL, Guo W, Quach B, Mulholland DJ, Park JW, Tran LM, Kobayashi N, Bianchi-Frias D, Xing Y, Nelson PS, Wu H.
Oncogene. 2016 Jul 21; 29(35)3781-95
High-Resolution Genomic Profiling of Disseminated Tumor Cells in Prostate Cancer.
Wu Y, Schoenborn JR, Morrissey C, Xia J, Larson S, Brown LG, Qu X, Lange PH, Nelson PS, Vessella RL, Fang M.
J Mol Diagn. 2016 Jan; 1(18)131-43
Hubbard GK, Mutton LN, Khalili M, McMullin RP, Hicks JL, Bianchi-Frias D, Horn LA, Kulac I, Moubarek MS, Nelson PS, Yegnasubramanian S, De Marzo AM, Bieberich CJ.
Cancer Res. 2016 Jan 15; 2(76)283-92
The Molecular Taxonomy of Primary Prostate Cancer.
Cancer Genome Atlas Research Network.
Cell. 2015 Nov 5; 4(163)1011-25
Newcomb LF, Thompson IM Jr, Boyer HD, Brooks JD, Carroll PR, Cooperberg MR, Dash A, Ellis WJ, Fazli L, Feng Z, Gleave ME, Kunju P, Lance RS, McKenney JK, Meng MV, Nicolas MM, Sanda MG, Simko J, So A, Tretiakova MS, Troyer DA, True LD, Vakar-Lopez F, Virgin J, Wagner AA, Wei JT, Zheng Y, Nelson PS, Lin DW, Canary PASS Investigators..
J Urol. 2016 Feb; 2(195)313-20
Integrative Clinical Genomics of Advanced Prostate Cancer.
Robinson D, Van Allen EM, Wu YM, Schultz N, Lonigro RJ, Mosquera JM, Montgomery B, Taplin ME, Pritchard CC, Attard G, Beltran H, Abida W, Bradley RK, Vinson J, Cao X, Vats P, Kunju LP, Hussain M, Feng FY, Tomlins SA, Cooney KA, Smith DC, Brennan C, Siddiqui J, Mehra R, Chen Y, Rathkopf DE, Morris MJ, Solomon SB, Durack JC, Reuter VE, Gopalan A, Gao J, Loda M, Lis RT, Bowden M, Balk SP, Gaviola G, Sougnez C, Gupta M, Yu EY, Mostaghel EA, Cheng HH, Mulcahy H, True LD, Plymate SR, Dvinge H, Ferraldeschi R, Flohr P, Miranda S, Zafeiriou Z, Tunariu N, Mateo J, Perez-Lopez R, Demichelis F, Robinson BD, Sboner A, Schiffman M, Nanus DM, Tagawa ST, Sigaras A, Eng KW, Elemento O, Sboner A, Heath EI, Scher HI, Pienta KJ, Kantoff P, de Bono JS, Rubin MA, Nelson PS, Garraway LA, Sawyers CL, Chinnaiyan AM.
Cell. 2015 Jul 16; 2(162)454
Brooks JD, Wei W, Hawley S, Auman H, Newcomb L, Boyer H, Fazli L, Simko J, Hurtado-Coll A, Troyer DA, Carroll PR, Gleave M, Lance R, Lin DW, Nelson PS, Thompson IM, True LD, Feng Z, McKenney JK.
PLoS One. 2015; 7(10)e0132343
Laberge RM, Sun Y, Orjalo AV, Patil CK, Freund A, Zhou L, Curran SC, Davalos AR, Wilson-Edell KA, Liu S, Limbad C, Demaria M, Li P, Hubbard GB, Ikeno Y, Javors M, Desprez PY, Benz CC, Kapahi P, Nelson PS, Campisi J.
Nat Cell Biol. 2015 Aug; 8(17)1049-61
Cellular Adhesion Promotes Prostate Cancer Cells Escape from Dormancy.
Ruppender N, Larson S, Lakely B, Kollath L, Brown L, Coleman I, Coleman R, Nguyen H, Nelson PS, Corey E, Snyder LA, Vessella RL, Morrissey C, Lam HM.
PLoS One. 2015; 6(10)e0130565
Zhang X, Coleman IM, Brown LG, True LD, Kollath L, Lucas JM, Lam HM, Dumpit R, Corey E, Chéry L, Lakely B, Higano CS, Montgomery B, Roudier M, Lange PH, Nelson PS, Vessella RL, Morrissey C.
Clin Cancer Res. 2015 Oct 15; 20(21)4698-708
Nguyen LT, Tretiakova MS, Silvis MR, Lucas J, Klezovitch O, Coleman I, Bolouri H, Kutyavin VI, Morrissey C, True LD, Nelson PS, Vasioukhin V.
Cancer Cell. 2015 Jun 8; 6(27)797-808
Gillessen S, Omlin A, Attard G, de Bono JS, Efstathiou E, Fizazi K, Halabi S, Nelson PS, Sartor O, Smith MR, Soule HR, Akaza H, Beer TM, Beltran H, Chinnaiyan AM, Daugaard G, Davis ID, De Santis M, Drake CG, Eeles RA, Fanti S, Gleave ME, Heidenreich A, Hussain M, James ND, Lecouvet FE, Logothetis CJ, Mastris K, Nilsson S, Oh WK, Olmos D, Padhani AR, Parker C, Rubin MA, Schalken JA, Scher HI, Sella A, Shore ND, Small EJ, Sternberg CN, Suzuki H, Sweeney CJ, Tannock IF, Tombal B.
Ann Oncol. 2015 Aug; 8(26)1589-604
Integrative clinical genomics of advanced prostate cancer.
Robinson D, Van Allen EM, Wu YM, Schultz N, Lonigro RJ, Mosquera JM, Montgomery B, Taplin ME, Pritchard CC, Attard G, Beltran H, Abida W, Bradley RK, Vinson J, Cao X, Vats P, Kunju LP, Hussain M, Feng FY, Tomlins SA, Cooney KA, Smith DC, Brennan C, Siddiqui J, Mehra R, Chen Y, Rathkopf DE, Morris MJ, Solomon SB, Durack JC, Reuter VE, Gopalan A, Gao J, Loda M, Lis RT, Bowden M, Balk SP, Gaviola G, Sougnez C, Gupta M, Yu EY, Mostaghel EA, Cheng HH, Mulcahy H, True LD, Plymate SR, Dvinge H, Ferraldeschi R, Flohr P, Miranda S, Zafeiriou Z, Tunariu N, Mateo J, Perez-Lopez R, Demichelis F, Robinson BD, Schiffman M, Nanus DM, Tagawa ST, Sigaras A, Eng KW, Elemento O, Sboner A, Heath EI, Scher HI, Pienta KJ, Kantoff P, de Bono JS, Rubin MA, Nelson PS, Garraway LA, Sawyers CL, Chinnaiyan AM.
Cell. 2015 May 21; 5(161)1215-1228
Expression of cell cycle-regulated genes and prostate cancer prognosis in a population-based cohort.
Rubicz R, Zhao S, April C, Wright JL, Kolb S, Coleman I, Lin DW, Nelson PS, Ostrander EA, Feng Z, Fan JB, Stanford JL.
Prostate. 2015 Sep; 13(75)1354-62
Troyer DA, Jamaspishvili T, Wei W, Feng Z, Good J, Hawley S, Fazli L, McKenney JK, Simko J, Hurtado-Coll A, Carroll PR, Gleave M, Lance R, Lin DW, Nelson PS, Thompson IM, True LD, Brooks JD, Squire JA.
Prostate. 2015 Aug 1; 11(75)1206-15
Hovelson DH, McDaniel AS, Cani AK, Johnson B, Rhodes K, Williams PD, Bandla S, Bien G, Choppa P, Hyland F, Gottimukkala R, Liu G, Manivannan M, Schageman J, Ballesteros-Villagrana E, Grasso CS, Quist MJ, Yadati V, Amin A, Siddiqui J, Betz BL, Knudsen KE, Cooney KA, Feng FY, Roh MH, Nelson PS, Liu CJ, Beer DG, Wyngaard P, Chinnaiyan AM, Sadis S, Rhodes DR, Tomlins SA.
Neoplasia. 2015 Apr; 4(17)385-99
Ankerst DP, Xia J, Thompson IM Jr, Hoefler J, Newcomb LF, Brooks JD, Carroll PR, Ellis WJ, Gleave ME, Lance RS, Nelson PS, Wagner AA, Wei JT, Etzioni R, Lin DW.
Eur Urol. 2015 Dec; 6(68)1083-8
Hsieh CL, Botta G, Gao S, Li T, Van Allen EM, Treacy DJ, Cai C, He HH, Sweeney CJ, Brown M, Balk SP, Nelson PS, Garraway LA, Kantoff PW.
Cancer Res. 2015 May 15; 10(75)1944-8
Integrative molecular profiling of routine clinical prostate cancer specimens.
Grasso CS, Cani AK, Hovelson DH, Quist MJ, Douville NJ, Yadati V, Amin AM, Nelson PS, Betz BL, Liu CJ, Knudsen KE, Cooney KA, Feng FY, McDaniel AS, Tomlins SA.
Ann Oncol. 2015 Jun; 6(26)1110-8
Huber RM, Lucas JM, Gomez-Sarosi LA, Coleman I, Zhao S, Coleman R, Nelson PS.
Oncotarget. 2015 Feb 10; 4(6)2134-47
Tamae D, Mostaghel E, Montgomery B, Nelson PS, Balk SP, Kantoff PW, Taplin ME, Penning TM.
Chem Biol Interact. 2015 Jun 5; (234)332-8
Mostaghel EA, Morgan A, Zhang X, Marck BT, Xia J, Hunter-Merrill R, Gulati R, Plymate S, Vessella RL, Corey E, Higano CS, Matsumoto AM, Montgomery RB, Nelson PS.
PLoS One. 2014; 10(9)e111545
Chen EJ, Sowalsky AG, Gao S, Cai C, Voznesensky O, Schaefer R, Loda M, True LD, Ye H, Troncoso P, Lis RL, Kantoff PW, Montgomery RB, Nelson PS, Bubley GJ, Balk SP, Taplin ME.
Clin Cancer Res. 2015 Mar 15; 6(21)1273-80
Taplin ME, Montgomery B, Logothetis CJ, Bubley GJ, Richie JP, Dalkin BL, Sanda MG, Davis JW, Loda M, True LD, Troncoso P, Ye H, Lis RT, Marck BT, Matsumoto AM, Balk SP, Mostaghel EA, Penning TM, Nelson PS, Xie W, Jiang Z, Haqq CM, Tamae D, Tran N, Peng W, Kheoh T, Molina A, Kantoff PW.
J Clin Oncol. 2014 Nov 20; 33(32)3705-15
Chéry L, Lam HM, Coleman I, Lakely B, Coleman R, Larson S, Aguirre-Ghiso JA, Xia J, Gulati R, Nelson PS, Montgomery B, Lange P, Snyder LA, Vessella RL, Morrissey C.
Oncotarget. 2014 Oct 30; 20(5)9939-51
The landscape of somatic chromosomal copy number aberrations in GEM models of prostate carcinoma.
Bianchi-Frias D, Hernandez SA, Coleman R, Wu H, Nelson PS.
Mol Cancer Res. 2015 Feb; 2(13)339-47
Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer.
Pritchard CC, Morrissey C, Kumar A, Zhang X, Smith C, Coleman I, Salipante SJ, Milbank J, Yu M, Grady WM, Tait JF, Corey E, Vessella RL, Walsh T, Shendure J, Nelson PS.
Nat Commun. 2014 Sep 25; (5)4988
Gordon RR, Wu M, Huang CY, Harris WP, Sim HG, Lucas JM, Coleman I, Higano CS, Gulati R, True LD, Vessella R, Lange PH, Garzotto M, Beer TM, Nelson PS.
PLoS One. 2014; 9(9)e104271
Targeting the androgen receptor in prostate cancer--a resilient foe.
Nelson PS
N Engl J Med. 2014 Sep 11; 11(371)1067-9
Lucas JM, Heinlein C, Kim T, Hernandez SA, Malik MS, True LD, Morrissey C, Corey E, Montgomery B, Mostaghel E, Clegg N, Coleman I, Brown CM, Schneider EL, Craik C, Simon JA, Bedalov A, Nelson PS.
Cancer Discov. 2014 Nov; 11(4)1310-25
Saar M, Zhao H, Nolley R, Young SR, Coleman I, Nelson PS, Vessella RL, Peehl DM.
Cancer Lett. 2014 Sep 1; 2(351)272-80
Garcia AJ, Ruscetti M, Arenzana TL, Tran LM, Bianci-Frias D, Sybert E, Priceman SJ, Wu L, Nelson PS, Smale ST, Wu H.
Mol Cell Biol. 2014 Jun; 11(34)2017-28
Tarnow C, Engels G, Arendt A, Schwalm F, Sediri H, Preuss A, Nelson PS, Garten W, Klenk HD, Gabriel G, Böttcher-Friebertshäuser E.
J Virol. 2014 May; 9(88)4744-51
Rapid induction of androgen receptor splice variants by androgen deprivation in prostate cancer.
Yu Z, Chen S, Sowalsky AG, Voznesensky OS, Mostaghel EA, Nelson PS, Cai C, Balk SP.
Clin Cancer Res. 2014 Mar 15; 6(20)1590-600
Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.
Hatesuer B, Bertram S, Mehnert N, Bahgat MM, Nelson PS, Pöhlmann S, Schughart K.
PLoS Pathog. 2013; 12(9)e1003774
Targeted androgen pathway suppression in localized prostate cancer: a pilot study.
Mostaghel EA, Nelson PS, Lange P, Lin DW, Taplin ME, Balk S, Ellis W, Kantoff P, Marck B, Tamae D, Matsumoto AM, True LD, Vessella R, Penning T, Hunter Merrill R, Gulati R, Montgomery B.
J Clin Oncol. 2014 Jan 20; 3(32)229-37
Larson SR, Chin J, Zhang X, Brown LG, Coleman IM, Lakely B, Tenniswood M, Corey E, Nelson PS, Vessella RL, Morrissey C.
Clin Exp Metastasis. 2014 Feb; 2(31)247-56
Qu X, Randhawa G, Friedman C, Kurland BF, Glaskova L, Coleman I, Mostaghel E, Higano CS, Porter C, Vessella R, Nelson PS, Fang M.
PLoS One. 2013; 9(8)e74671
AR variant ARv567es induces carcinogenesis in a novel transgenic mouse model of prostate cancer.
Liu G, Sprenger C, Sun S, Epilepsia KS, Haugk K, Zhang X, Coleman I, Nelson PS, Plymate S.
Neoplasia. 2013 Sep; 9(15)1009-17
A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer.
Chang KH, Li R, Kuri B, Lotan Y, Roehrborn CG, Liu J, Vessella R, Nelson PS, Kapur P, Guo X, Mirzaei H, Auchus RJ, Sharifi N.
Cell. 2013 Aug 29; 5(154)1074-1084
Cheng HH, Mitchell PS, Kroh EM, Dowell AE, Chéry L, Siddiqui J, Nelson PS, Vessella RL, Knudsen BS, Chinnaiyan AM, Pienta KJ, Morrissey C, Tewari M.
PLoS One. 2013; 7(8)e69239
Tamae D, Byrns M, Marck B, Mostaghel EA, Nelson PS, Lange P, Lin D, Taplin ME, Balk S, Ellis W, True L, Vessella R, Montgomery B, Blair IA, Penning TM.
J Steroid Biochem Mol Biol. 2013 Nov; (138)281-9
Leveraging the species barrier to advance cancer therapy.
Zhao S, Nelson PS.
Nat Genet. 2013 Jul; 7(45)718-20
Dean JP, Sprenger CC, Wan J, Haugk K, Ellis WJ, Lin DW, Corman JM, Dalkin BL, Mostaghel E, Nelson PS, Cohen P, Montgomery B, Plymate SR.
J Clin Endocrinol Metab. 2013 May; 5(98)E820-8
Lin DW, Newcomb LF, Brown EC, Brooks JD, Carroll PR, Feng Z, Gleave ME, Lance RS, Sanda MG, Thompson IM, Wei JT, Nelson PS, Canary Prostate Active Surveillance Study Investigators..
Clin Cancer Res. 2013 May 1; 9(19)2442-50
Bluemn EG, Spencer ES, Mecham B, Gordon RR, Coleman I, Lewinshtein D, Mostaghel E, Zhang X, Annis J, Grandori C, Porter C, Nelson PS.
Mol Cancer Res. 2013 Jun; 6(11)568-78
Single cell transcriptomic analysis of prostate cancer cells.
Welty CJ, Coleman I, Coleman R, Lakely B, Xia J, Chen S, Gulati R, Larson SR, Lange PH, Montgomery B, Nelson PS, Vessella RL, Morrissey C.
BMC Mol Biol. 2013 Feb 16; (14)6
Prostate cancer cell phenotypes based on AGR2 and CD10 expression.
Ho ME, Quek SI, True LD, Morrissey C, Corey E, Vessella RL, Dumpit R, Nelson PS, Maresh EL, Mah V, Alavi M, Kim SR, Bagryanova L, Horvath S, Chia D, Goodglick L, Liu AY.
Mod Pathol. 2013 Jun; 6(26)849-59
Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases.
Larson SR, Zhang X, Dumpit R, Coleman I, Lakely B, Roudier M, Higano CS, True LD, Lange PH, Montgomery B, Corey E, Nelson PS, Vessella RL, Morrissey C.
Prostate. 2013 Jun; 9(73)932-40
Prognostic value of ERG oncoprotein in prostate cancer recurrence and cause-specific mortality.
Spencer ES, Johnston RB, Gordon RR, Lucas JM, Ussakli CH, Hurtado-Coll A, Srivastava S, Nelson PS, Porter CR.
Prostate. 2013 Jun; 9(73)905-12
Launching of american journal of clinical and experimental urology.
Terris MK, Wang Z, Culig Z, Twiss CO, Lee P, Nelson PS.
Am J Clin Exp Urol. 2013; 1(1)1-2
Hawley S, Fazli L, McKenney JK, Simko J, Troyer D, Nicolas M, Newcomb LF, Cowan JE, Crouch L, Ferrari M, Hernandez J, Hurtado-Coll A, Kuchinsky K, Liew J, Mendez-Meza R, Smith E, Tenggara I, Zhang X, Carroll PR, Chan JM, Gleave M, Lance R, Lin DW, Nelson PS, Thompson IM, Feng Z, True LD, Brooks JD.
Adv Anat Pathol. 2013 Jan; 1(20)39-44
Sun Y, Campisi J, Higano C, Beer TM, Porter P, Coleman I, True L, Nelson PS.
Nat Med. 2012 Sep; 9(18)1359-68
Goel HL, Chang C, Pursell B, Leav I, Lyle S, Xi HS, Hsieh CC, Adisetiyo H, Roy-Burman P, Coleman IM, Nelson PS, Vessella RL, Davis RJ, Plymate SR, Mercurio AM.
Cancer Discov. 2012 Oct; 10(2)906-21
Hu R, Lu C, Mostaghel EA, Yegnasubramanian S, Gurel M, Tannahill C, Edwards J, Isaacs WB, Nelson PS, Bluemn E, Plymate SR, Luo J.
Cancer Res. 2012 Jul 15; 14(72)3457-62
Mostaghel EA, Lin DW, Amory JK, Wright JL, Marck BT, Nelson PS, Matsumoto AM, Bremner WJ, Page ST.
J Clin Endocrinol Metab. 2012 Aug; 8(97)2809-17
Molecular pathways: involving microenvironment damage responses in cancer therapy resistance.
Sun Y, Nelson PS.
Clin Cancer Res. 2012 Aug 1; 15(18)4019-25
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.
Barbieri CE, Baca SC, Lawrence MS, Demichelis F, Blattner M, Theurillat JP, White TA, Stojanov P, Van Allen E, Stransky N, Nickerson E, Chae SS, Boysen G, Auclair D, Onofrio RC, Park K, Kitabayashi N, MacDonald TY, Sheikh K, Vuong T, Guiducci C, Cibulskis K, Sivachenko A, Carter SL, Saksena G, Voet D, Hussain WM, Ramos AH, Winckler W, Redman MC, Ardlie K, Tewari AK, Mosquera JM, Rupp N, Wild PJ, Moch H, Morrissey C, Nelson PS, Kantoff PW, Gabriel SB, Golub TR, Meyerson M, Lander ES, Getz G, Rubin MA, Garraway LA.
Nat Genet. 2012 May 20; 6(44)685-9
Bertram S, Heurich A, Lavender H, Gierer S, Danisch S, Perin P, Lucas JM, Nelson PS, Pöhlmann S, Soilleux EJ.
PLoS One. 2012; 4(7)e35876
Whitmore TE, Peterson A, Holzman T, Eastham A, Amon L, McIntosh M, Ozinsky A, Nelson PS, Martin DB.
J Proteome Res. 2012 May 4; 5(11)2653-65
The monoamine oxidase A gene promoter repeat and prostate cancer risk.
White TA, Kwon EM, Fu R, Lucas JM, Ostrander EA, Stanford JL, Nelson PS.
Prostate. 2012 Nov; 15(72)1622-7
Androgen action and metabolism in prostate cancer.
Green SM, Mostaghel EA, Nelson PS.
Mol Cell Endocrinol. 2012 Sep 5; 1-2(360)3-13
Cellular senescence and cancer chemotherapy resistance.
Gordon RR, Nelson PS.
Drug Resist Updat. 2012 Feb-Apr; 1-2(15)123-31
The androgen/androgen receptor axis in prostate cancer.
Bluemn EG, Nelson PS.
Curr Opin Oncol. 2012 May; 3(24)251-7
Nelson PS
J Clin Oncol. 2012 Feb 20; 6(30)644-6
Androgen receptor variants occur frequently in castration resistant prostate cancer metastases.
Zhang X, Morrissey C, Sun S, Ketchandji M, Nelson PS, True LD, Vakar-Lopez F, Vessella RL, Plymate SR.
PLoS One. 2011; 11(6)e27970
Cai C, He HH, Chen S, Coleman I, Wang H, Fang Z, Chen S, Nelson PS, Liu XS, Brown M, Balk SP.
Cancer Cell. 2011 Oct 18; 4(20)457-71
Kumar A, White TA, MacKenzie AP, Clegg N, Lee C, Dumpit RF, Coleman I, Ng SB, Salipante SJ, Rieder MJ, Nickerson DA, Corey E, Lange PH, Morrissey C, Vessella RL, Nelson PS, Shendure J.
Proc Natl Acad Sci U S A. 2011 Oct 11; 41(108)17087-92
Lewinshtein D, Gulati R, Nelson PS, Porter CR.
BJU Int. 2012 Mar; 5(109)706-12
Cai C, Chen S, Ng P, Bubley GJ, Nelson PS, Mostaghel EA, Marck B, Matsumoto AM, Simon NI, Wang H, Chen S, Balk SP.
Cancer Res. 2011 Oct 15; 20(71)6503-13
Mostaghel EA, Marck BT, Plymate SR, Vessella RL, Balk S, Matsumoto AM, Nelson PS, Montgomery RB.
Clin Cancer Res. 2011 Sep 15; 18(17)5913-25
Testosterone regulates tight junction proteins and influences prostatic autoimmune responses.
Meng J, Mostaghel EA, Vakar-Lopez F, Montgomery B, True L, Nelson PS.
Horm Cancer. 2011 Jun; 3(2)145-56
Metastatic progression of prostate cancer and e-cadherin regulation by zeb1 and SRC family kinases.
Putzke AP, Ventura AP, Bailey AM, Akture C, Opoku-Ansah J, CeliktaĹź M, Hwang MS, Darling DS, Coleman IM, Nelson PS, Nguyen HM, Corey E, Tewari M, Morrissey C, Vessella RL, Knudsen BS.
Am J Pathol. 2011 Jul; 1(179)400-10
A targeted proteomics-based pipeline for verification of biomarkers in plasma.
Whiteaker JR, Lin C, Kennedy J, Hou L, Trute M, Sokal I, Yan P, Schoenherr RM, Zhao L, Voytovich UJ, Kelly-Spratt KS, Krasnoselsky A, Gafken PR, Hogan JM, Jones LA, Wang P, Amon L, Chodosh LA, Nelson PS, McIntosh MW, Kemp CJ, Paulovich AG.
Nat Biotechnol. 2011 Jun 19; 7(29)625-34
Pitteri SJ, Kelly-Spratt KS, Gurley KE, Kennedy J, Buson TB, Chin A, Wang H, Zhang Q, Wong CH, Chodosh LA, Nelson PS, Hanash SM, Kemp CJ.
Cancer Res. 2011 Aug 1; 15(71)5090-100
Zhang S, Wang X, Osunkoya AO, Iqbal S, Wang Y, Chen Z, MĂĽller S, Chen Z, Josson S, Coleman IM, Nelson PS, Wang YA, Wang R, Shin DM, Marshall FF, Kucuk O, Chung LW, Zhau HE, Wu D.
Oncogene. 2011 Dec 15; 50(30)4941-52
Kumar A, Shendure J, Nelson PS.
Genome Med. 2011 Apr 19; 4(3)23
Proteome and transcriptome profiles of a Her2/Neu-driven mouse model of breast cancer.
Schoenherr RM, Kelly-Spratt KS, Lin C, Whiteaker JR, Liu T, Holzman T, Coleman I, Feng LC, Lorentzen TD, Krasnoselsky AL, Wang P, Liu Y, Gurley KE, Amon LM, Schepmoes AA, Moore RJ, Camp DG 2nd, Chodosh LA, Smith RD, Nelson PS, McIntosh MW, Kemp CJ, Paulovich AG.
Proteomics Clin Appl. 2011 Apr; 3-4(5)179-88
IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR.
Rojas A, Liu G, Coleman I, Nelson PS, Zhang M, Dash R, Fisher PB, Plymate SR, Wu JD.
Oncogene. 2011 May 19; 20(30)2345-55
Page ST, Lin DW, Mostaghel EA, Marck BT, Wright JL, Wu J, Amory JK, Nelson PS, Matsumoto AM.
J Clin Endocrinol Metab. 2011 Feb; 2(96)430-7
Sharma A, Yeow WS, Ertel A, Coleman I, Clegg N, Thangavel C, Morrissey C, Zhang X, Comstock CE, Witkiewicz AK, Gomella L, Knudsen ES, Nelson PS, Knudsen KE.
J Clin Invest. 2010 Dec; 12(120)4478-92
Intraprostatic steroidogenic enzymes - letter.
Mostaghel E, Nelson PS, Nelson C, Montgomery RB.
Cancer Res. 2010 Oct 15; 20(70)8247-9; author reply 8249-50
Risk MC, Knudsen BS, Coleman I, Dumpit RF, Kristal AR, LeMeur N, Gentleman RC, True LD, Nelson PS, Lin DW.
Clin Cancer Res. 2010 Nov 15; 22(16)5414-23
The effects of aging on the molecular and cellular composition of the prostate microenvironment.
Bianchi-Frias D, Vakar-Lopez F, Coleman IM, Plymate SR, Reed MJ, Nelson PS.
PLoS One. 2010 Sep 1; 9(5)
Salinas CA, Kwon EM, FitzGerald LM, Feng Z, Nelson PS, Ostrander EA, Peters U, Stanford JL.
Am J Epidemiol. 2010 Sep 1; 5(172)578-90
Sun S, Sprenger CC, Vessella RL, Haugk K, Soriano K, Mostaghel EA, Page ST, Coleman IM, Nguyen HM, Sun H, Nelson PS, Plymate SR.
J Clin Invest. 2010 Aug; 8(120)2715-30
Genomic predictors of prostate cancer therapy outcomes.
Lewinshtein DJ, Porter CR, Nelson PS.
Expert Rev Mol Diagn. 2010 Jul; 5(10)619-36
True LD, Zhang H, Ye M, Huang CY, Nelson PS, von Haller PD, Tjoelker LW, Kim JS, Qian WJ, Smith RD, Ellis WJ, Liebeskind ES, Liu AY.
Mod Pathol. 2010 Oct; 10(23)1346-56
Montgomery B, Nelson PS, Vessella R, Kalhorn T, Hess D, Corey E.
BMC Cancer. 2010 May 28; (10)244
Yu EY, Gulati R, Telesca D, Jiang P, Tam S, Russell KJ, Nelson PS, Etzioni RD, Higano CS.
J Clin Oncol. 2010 Jun 1; 16(28)2668-73
ID1 enhances docetaxel cytotoxicity in prostate cancer cells through inhibition of p21.
Geng H, Rademacher BL, Pittsenbarger J, Huang CY, Harvey CT, Lafortune MC, Myrthue A, Garzotto M, Nelson PS, Beer TM, Qian DZ.
Cancer Res. 2010 Apr 15; 8(70)3239-48
Supervised normalization of microarrays.
Mecham BH, Nelson PS, Storey JD.
Bioinformatics. 2010 May 15; 10(26)1308-15
He H, Xu J, Nelson PS, Marshall FF, Chung LW, Zhau HE, He D, Wang R.
Prostate. 2010 Jun 15; 9(70)993-1001
Mostaghel EA, Geng L, Holcomb I, Coleman IM, Lucas J, True LD, Nelson PS.
Cancer Res. 2010 Feb 15; 4(70)1286-95
Damodarasamy M, Vernon RB, Karres N, Chang CH, Bianchi-Frias D, Nelson PS, Reed MJ.
J Gerontol A Biol Sci Med Sci. 2010 Mar; 3(65)209-18
Sprenger CC, Haugk K, Sun S, Coleman I, Nelson PS, Vessella RL, Ludwig DL, Wu JD, Plymate SR.
Clin Cancer Res. 2009 Dec 15; 24(15)7634-7641
Wang D, Montgomery RB, Schmidt LJ, Mostaghel EA, Huang H, Nelson PS, Tindall DJ.
Cancer Res. 2009 Dec 15; 24(69)9448-56
HE3235 inhibits growth of castration-resistant prostate cancer.
Koreckij TD, Trauger RJ, Montgomery RB, Pitts TE, Coleman I, Nguyen H, Reading CL, Nelson PS, Vessella RL, Corey E.
Neoplasia. 2009 Nov; 11(11)1216-25
Qian DZ, Rademacher BL, Pittsenbarger J, Huang CY, Myrthue A, Higano CS, Garzotto M, Nelson PS, Beer TM.
Prostate. 2010 Mar 1; 4(70)433-42
Morrissey C, Lai JS, Brown LG, Wang YC, Roudier MP, Coleman IM, Gulati R, Vakar-Lopez F, True LD, Corey E, Nelson PS, Vessella RL.
Prostate. 2010 Mar 1; 4(70)412-24
Holcomb IN, Young JM, Coleman IM, Salari K, Grove DI, Hsu L, True LD, Roudier MP, Morrissey CM, Higano CS, Nelson PS, Vessella RL, Trask BJ.
Cancer Res. 2009 Oct 1; 19(69)7793-802
Newcomb LF, Brooks JD, Carroll PR, Feng Z, Gleave ME, Nelson PS, Thompson IM, Lin DW.
Urology. 2010 Feb; 2(75)407-13
Cooperberg MR, Hinotsu S, Chancellor MB, Homma Y, Nelson PS, Matsuyama H, Menon M, Kucuk O, Hara I, Egawa S, Uzzo RG, Kanayama HO, Okuyama A, Akaza H.
Int J Urol. 2009 Aug; 8(16)703-8
A patient with coexistent bullous pemphigoid and primary membranous glomerulonephropathy.
Soine EJ, Nelson PS, Nesbitt LT Jr.
J Am Acad Dermatol. 2009 Jun; 6(60)1042-4
Castration-resistant prostate cancer: targeting androgen metabolic pathways in recurrent disease.
Mostaghel EA, Montgomery B, Nelson PS.
Urol Oncol. 2009 May-Jun; 3(27)251-7
Prostate cancer-associated gene expression alterations determined from needle biopsies.
Qian DZ, Huang CY, O'Brien CA, Coleman IM, Garzotto M, True LD, Higano CS, Vessella R, Lange PH, Nelson PS, Beer TM.
Clin Cancer Res. 2009 May 1; 9(15)3135-42
Genomic strategy for targeting therapy in castration-resistant prostate cancer.
Mendiratta P, Mostaghel E, Guinney J, Tewari AK, Porrello A, Barry WT, Nelson PS, Febbo PG.
J Clin Oncol. 2009 Apr 20; 12(27)2022-9
Conserved gene expression programs integrate mammalian prostate development and tumorigenesis.
Pritchard C, Mecham B, Dumpit R, Coleman I, Bhattacharjee M, Chen Q, Sikes RA, Nelson PS.
Cancer Res. 2009 Mar 1; 5(69)1739-47
Harris WP, Mostaghel EA, Nelson PS, Montgomery B.
Nat Clin Pract Urol. 2009 Feb; 2(6)76-85
Bluemn EG, Paulson KG, Higgins EE, Sun Y, Nghiem P, Nelson PS.
J Clin Virol. 2009 Feb; 2(44)164-6
Coppé JP, Patil CK, Rodier F, Sun Y, Muñoz DP, Goldstein J, Nelson PS, Desprez PY, Campisi J.
PLoS Biol. 2008 Dec 2; 12(6)2853-68
Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment.
Arnold RS, Sun CQ, Richards JC, Grigoriev G, Coleman IM, Nelson PS, Hsieh CL, Lee JK, Xu Z, Rogatko A, Osunkoya AO, Zayzafoon M, Chung L, Petros JA.
Prostate. 2009 Jan 1; 1(69)1-11
Circulating microRNAs as stable blood-based markers for cancer detection.
Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, Peterson A, Noteboom J, O'Briant KC, Allen A, Lin DW, Urban N, Drescher CW, Knudsen BS, Stirewalt DL, Gentleman R, Vessella RL, Nelson PS, Martin DB, Tewari M.
Proc Natl Acad Sci U S A. 2008 Jul 29; 30(105)10513-8
Holcomb IN, Grove DI, Kinnunen M, Friedman CL, Gallaher IS, Morgan TM, Sather CL, Delrow JJ, Nelson PS, Lange PH, Ellis WJ, True LD, Young JM, Hsu L, Trask BJ, Vessella RL.
Cancer Res. 2008 Jul 15; 14(68)5599-608
Tischkowitz MD, Yilmaz A, Chen LQ, Karyadi DM, Novak D, Kirchhoff T, Hamel N, Tavtigian SV, Kolb S, Bismar TA, Aloyz R, Nelson PS, Hood L, Narod SA, White KA, Ostrander EA, Isaacs WB, Offit K, Cooney KA, Stanford JL, Foulkes WD.
Cancer Lett. 2008 Oct 18; 1(270)173-80
Association of megalin genetic polymorphisms with prostate cancer risk and prognosis.
Holt SK, Karyadi DM, Kwon EM, Stanford JL, Nelson PS, Ostrander EA.
Clin Cancer Res. 2008 Jun 15; 12(14)3823-31
Montgomery RB, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, Higano CS, True LD, Nelson PS.
Cancer Res. 2008 Jun 1; 11(68)4447-54
Prostate tissue androgens: history and current clinical relevance.
Marks LS, Mostaghel EA, Nelson PS.
Urology. 2008 Aug; 2(72)247-54
Pascal LE, True LD, Campbell DS, Deutsch EW, Risk M, Coleman IM, Eichner LJ, Nelson PS, Liu AY.
BMC Genomics. 2008 May 23; (9)246
Mostaghel EA, Nelson PS.
Best Pract Res Clin Endocrinol Metab. 2008 Apr; 2(22)243-58
Gene expression profiling in the developing prostate.
Pritchard CC, Nelson PS.
Differentiation. 2008 Jul; 6(76)624-40
Lucas JM, True L, Hawley S, Matsumura M, Morrissey C, Vessella R, Nelson PS.
J Pathol. 2008 Jun; 2(215)118-25
Lin B, Utleg AG, Gravdal K, White JT, Halvorsen OJ, Lu W, True LD, Vessella R, Lange PH, Nelson PS, Hood L, Kalland KH, Akslen LA.
Clin Cancer Res. 2008 Mar 1; 5(14)1397-406
Sclerosing sweat duct carcinoma in a 6-year-old African American child.
Nelson PS, Bourgeois KM, Nicotri T Jr, Chiu ES, Poole JC.
Pediatr Dermatol. 2008 Jan-Feb; 1(25)38-42
A causal role for ERG in neoplastic transformation of prostate epithelium.
Klezovitch O, Risk M, Coleman I, Lucas JM, Null M, True LD, Nelson PS, Vasioukhin V.
Proc Natl Acad Sci U S A. 2008 Feb 12; 6(105)2105-10
Profiling influences of senescent and aged fibroblasts on prostate carcinogenesis.
Dean JP, Nelson PS.
Br J Cancer. 2008 Jan 29; 2(98)245-9
The role of tissue microarrays in prostate cancer biomarker discovery.
Datta MW, True LD, Nelson PS, Amin MB.
Adv Anat Pathol. 2007 Nov; 6(14)408-18
Morrissey C, True LD, Roudier MP, Coleman IM, Hawley S, Nelson PS, Coleman R, Wang YC, Corey E, Lange PH, Higano CS, Vessella RL.
Clin Exp Metastasis. 2008; 4(25)377-88
Lin DW, Neuhouser ML, Schenk JM, Coleman IM, Hawley S, Gifford D, Hung H, Knudsen BS, Nelson PS, Kristal AR.
Cancer Epidemiol Biomarkers Prev. 2007 Oct; 10(16)2150-4
Huang CY, Beer TM, Higano CS, True LD, Vessella R, Lange PH, Garzotto M, Nelson PS.
Clin Cancer Res. 2007 Oct 1; 19(13)5825-33
Xu C, Graf LF, Fazli L, Coleman IM, Mauldin DE, Li D, Nelson PS, Gleave M, Plymate SR, Cox ME, Torok-Storb BJ, Knudsen BS.
Prostate. 2007 Nov 1; 15(67)1621-9
Tissue-specific consequences of cyclin D1 overexpression in prostate cancer progression.
He Y, Franco OE, Jiang M, Williams K, Love HD, Coleman IM, Nelson PS, Hayward SW.
Cancer Res. 2007 Sep 1; 17(67)8188-97
Kalhorn TF, Page ST, Howald WN, Mostaghel EA, Nelson PS.
Rapid Commun Mass Spectrom. 2007; 19(21)3200-6
Montgomery RB, Nelson PS, Lin D, Ryan CW, Garzotto M, Beer TM.
Cancer. 2007 Sep 1; 5(110)996-1002
Genetic background influences murine prostate gene expression: implications for cancer phenotypes.
Bianchi-Frias D, Pritchard C, Mecham BH, Coleman IM, Nelson PS.
Genome Biol. 2007; 6(8)R117
Mostaghel EA, Page ST, Lin DW, Fazli L, Coleman IM, True LD, Knudsen B, Hess DL, Nelson CC, Matsumoto AM, Bremner WJ, Gleave ME, Nelson PS.
Cancer Res. 2007 May 15; 10(67)5033-41
Marks LS, Mazer NA, Mostaghel E, Hess DL, Dorey FJ, Epstein JI, Veltri RW, Makarov DV, Partin AW, Bostwick DG, Macairan ML, Nelson PS.
JAMA. 2006 Nov 15; 19(296)2351-61
Coleman IM, Kiefer JA, Brown LG, Pitts TE, Nelson PS, Brubaker KD, Vessella RL, Corey E.
Neoplasia. 2006 Oct; 10(8)862-78
Microarray analysis and tumor classification.
Lin DW, Nelson PS.
N Engl J Med. 2006 Aug 31; 9(355)960; author reply 960
Persistent intraprostatic androgen concentrations after medical castration in healthy men.
Page ST, Lin DW, Mostaghel EA, Hess DL, True LD, Amory JK, Nelson PS, Matsumoto AM, Bremner WJ.
J Clin Endocrinol Metab. 2006 Oct; 10(91)3850-6
A molecular correlate to the Gleason grading system for prostate adenocarcinoma.
True L, Coleman I, Hawley S, Huang CY, Gifford D, Coleman R, Beer TM, Gelmann E, Datta M, Mostaghel E, Knudsen B, Lange P, Vessella R, Lin D, Hood L, Nelson PS.
Proc Natl Acad Sci U S A. 2006 Jul 18; 29(103)10991-6
Lin DW, Coleman IM, Hawley S, Huang CY, Dumpit R, Gifford D, Kezele P, Hung H, Knudsen BS, Kristal AR, Nelson PS.
J Clin Oncol. 2006 Aug 10; 23(24)3763-70
The contributions of normal variation and genetic background to mammalian gene expression.
Pritchard C, Coil D, Hawley S, Hsu L, Nelson PS.
Genome Biol. 2006; 3(7)R26
Lu W, Zhou D, Glusman G, Utleg AG, White JT, Nelson PS, Vasicek TJ, Hood L, Lin B.
Prostate. 2006 Jun 15; 9(66)936-44
Chen Q, Watson JT, Marengo SR, Decker KS, Coleman I, Nelson PS, Sikes RA.
Cancer Lett. 2006 Dec 8; 2(244)274-88
Cell type-specific analyses for identifying prostate cancer biomarkers.
Nelson PS, Montgomery B.
Curr Urol Rep. 2006 Jan; 1(7)57-63
Phenotypic analysis of mice lacking the Tmprss2-encoded protease.
Kim TS, Heinlein C, Hackman RC, Nelson PS.
Mol Cell Biol. 2006 Feb; 3(26)965-75
Increased expression of osteopontin contributes to the progression of prostate cancer.
Khodavirdi AC, Song Z, Yang S, Zhong C, Wang S, Wu H, Pritchard C, Nelson PS, Roy-Burman P.
Cancer Res. 2006 Jan 15; 2(66)883-8
Bavik C, Coleman I, Dean JP, Knudsen B, Plymate S, Nelson PS.
Cancer Res. 2006 Jan 15; 2(66)794-802
Page ST, Plymate SR, Bremner WJ, Matsumoto AM, Hess DL, Lin DW, Amory JK, Nelson PS, Wu JD.
Am J Physiol Endocrinol Metab. 2006 May; 5(290)E856-63
York TP, Plymate SR, Nelson PS, Eaves LJ, Webb HD, Ware JL.
Mol Carcinog. 2005 Dec; 4(44)242-51
Fraser MM, Watson PM, Fraig MM, Kelley JR, Nelson PS, Boylan AM, Cole DJ, Watson DK.
Cancer Res. 2005 Jul 15; 14(65)6228-36
Knudsen BS, Lucas JM, Fazli L, Hawley S, Falcon S, Coleman IM, Martin DB, Xu C, True LD, Gleave ME, Nelson PS, Ayala GE.
Am J Pathol. 2005 Jul; 1(167)255-66
Estrogen effects on tubulin expression and taxane mediated cytotoxicity in prostate cancer cells.
Montgomery RB, Bonham M, Nelson PS, Grim J, Makary E, Vessella R, Stahl WL.
Prostate. 2005 Oct 1; 2(65)141-50
Bonham M, Posakony J, Coleman I, Montgomery B, Simon J, Nelson PS.
Clin Cancer Res. 2005 May 15; 10(11)3905-14
Belyaeva OV, Korkina OV, Stetsenko AV, Kim T, Nelson PS, Kedishvili NY.
Biochemistry. 2005 May 10; 18(44)7035-47
Kim TS, Maeda A, Maeda T, Heinlein C, Kedishvili N, Palczewski K, Nelson PS.
J Biol Chem. 2005 Mar 11; 10(280)8694-704
Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma.
Moore S, Knudsen B, True LD, Hawley S, Etzioni R, Wade C, Gifford D, Coleman I, Nelson PS.
Int J Cancer. 2005 Apr 20; 4(114)563-71
Predicting prostate cancer behavior using transcript profiles.
Nelson PS
J Urol. 2004 Nov; 5 Pt 2(172)S28-32; discussion S33
Carroll PR, Chan JM, D'Amico AV, Gelmann EP, Iversen P, Klotz L, Nelson JB, Nelson PS, Nelson WG, Oh WK, Rosen N, Rubin MA, Sandler H, Sellers WR, Smith MR, Xu J, McMann MC, Kantoff PW.
J Urol. 2004 Nov; 5 Pt 2(172)S3-5
Matsumura M, Bhatt AS, Andress D, Clegg N, Takayama TK, Craik CS, Nelson PS.
Prostate. 2005 Jan 1; 1(62)1-13
Plymate SR, Tennant MK, Culp SH, Woodke L, Marcelli M, Colman I, Nelson PS, Carroll JM, Roberts CT Jr, Ware JL.
Prostate. 2004 Nov 1; 3(61)276-90
Bayesian integrated functional analysis of microarray data.
Bhattacharjee M, Pritchard CC, Nelson PS, Arjas E.
Bioinformatics. 2004 Nov 22; 17(20)2943-53
Clegg N, Abbott D, Ferguson C, Coleman R, Nelson PS.
Prostate. 2004 Aug 1; 3(60)227-39
Drivdahl R, Haugk KH, Sprenger CC, Nelson PS, Tennant MK, Plymate SR.
Oncogene. 2004 Jun 3; 26(23)4584-93
The role of cyclooxygenase-2 inhibition for the prevention and treatment of prostate carcinoma.
Lin DW, Nelson PS.
Clin Prostate Cancer. 2003 Sep; 2(2)119-26
Wang R, Xu J, Saramäki O, Visakorpi T, Sutherland WM, Zhou J, Sen B, Lim SD, Mabjeesh N, Amin M, Dong JT, Petros JA, Nelson PS, Marshall FF, Zhau HE, Chung LW.
Cancer Res. 2004 Mar 1; 5(64)1589-94
Quantitative proteomic analysis of proteins released by neoplastic prostate epithelium.
Martin DB, Gifford DR, Wright ME, Keller A, Yi E, Goodlett DR, Aebersold R, Nelson PS.
Cancer Res. 2004 Jan 1; 1(64)347-55
Wright ME, Eng J, Sherman J, Hockenbery DM, Nelson PS, Galitski T, Aebersold R.
Genome Biol. 2003; 1(5)R4
Unconventional therapy for prostate cancer: good, bad or questionable?
Nelson PS, Montgomery B.
Nat Rev Cancer. 2003 Nov; 11(3)845-58
Abbott DE, Pritchard C, Clegg NJ, Ferguson C, Dumpit R, Sikes RA, Nelson PS.
Genome Biol. 2003; 12(4)R79
Schuster JM, Longo M, Nelson PS.
J Neurooncol. 2003 Sep; 3(64)219-25
Wang S, Gao J, Lei Q, Rozengurt N, Pritchard C, Jiao J, Thomas GV, Li G, Roy-Burman P, Nelson PS, Liu X, Wu H.
Cancer Cell. 2003 Sep; 3(4)209-21
Lin B, White JT, Utleg AG, Wang S, Ferguson C, True LD, Vessella R, Hood L, Nelson PS.
Genomics. 2003 Sep; 3(82)331-42
LuCaP 35: a new model of prostate cancer progression to androgen independence.
Corey E, Quinn JE, Buhler KR, Nelson PS, Macoska JA, True LD, Vessella RL.
Prostate. 2003 Jun 1; 4(55)239-46
Molecular characterization of prostatic small-cell neuroendocrine carcinoma.
Clegg N, Ferguson C, True LD, Arnold H, Moorman A, Quinn JE, Vessella RL, Nelson PS.
Prostate. 2003 Apr 1; 1(55)55-64
Plymate SR, Haugk KH, Sprenger CC, Nelson PS, Tennant MK, Zhang Y, Oberley LW, Zhong W, Drivdahl R, Oberley TD.
Oncogene. 2003 Feb 20; 7(22)1024-34
Nelson PS
Ann N Y Acad Sci. 2002 Dec; (975)232-46
Bonham MJ, Galkin A, Montgomery B, Stahl WL, Agus D, Nelson PS.
J Natl Cancer Inst. 2002 Nov 6; 21(94)1641-7
Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina.
Haeseleer F, Jang GF, Imanishi Y, Driessen CAGG, Matsumura M, Nelson PS, Palczewski K.
J Biol Chem. 2002 Nov 22; 47(277)45537-45546
The program of androgen-responsive genes in neoplastic prostate epithelium.
Nelson PS, Clegg N, Arnold H, Ferguson C, Bonham M, White J, Hood L, Lin B.
Proc Natl Acad Sci U S A. 2002 Sep 3; 18(99)11890-5
Aigner A, Renneberg H, Bojunga J, Apel J, Nelson PS, Czubayko F.
Oncogene. 2002 Aug 22; 37(21)5733-42
A neuroendocrine/small cell prostate carcinoma xenograft-LuCaP 49.
True LD, Buhler K, Quinn J, Williams E, Nelson PS, Clegg N, Macoska JA, Norwood T, Liu A, Ellis W, Lange P, Vessella R.
Am J Pathol. 2002 Aug; 2(161)705-15
Moore S, Pritchard C, Lin B, Ferguson C, Nelson PS.
Gene. 2002 Jun 26; 1-2(293)149-60
Bonham M, Arnold H, Montgomery B, Nelson PS.
Cancer Res. 2002 Jul 15; 14(62)3920-4
Kedishvili NY, Chumakova OV, Chetyrkin SV, Belyaeva OV, Lapshina EA, Lin DW, Matsumura M, Nelson PS.
J Biol Chem. 2002 Aug 9; 32(277)28909-15
Large-scale proteomics and its future impact on medicine.
Corthals GL, Nelson PS.
Pharmacogenomics J. 2001; 1(1)15-9
Gene expression profiling of the human prostate androgen response program.
Moore SM, Nelson PS.
J Androl. 2002 Mar-Apr; 2(23)163-9
Digital expression profiles of the prostate androgen-response program.
Clegg N, Eroglu B, Ferguson C, Arnold H, Moorman A, Nelson PS.
J Steroid Biochem Mol Biol. 2002 Jan; 1(80)13-23
Human prostate epithelial cell-type cDNA libraries and prostate expression patterns.
Liu AY, Nelson PS, van den Engh G, Hood L.
Prostate. 2002 Feb 1; 2(50)92-103
The human (PEDB) and mouse (mPEDB) Prostate Expression Databases.
Nelson PS, Pritchard C, Abbott D, Clegg N.
Nucleic Acids Res. 2002 Jan 1; 1(30)218-20
Takayama TK, McMullen BA, Nelson PS, Matsumura M, Fujikawa K.
Biochemistry. 2001 Dec 18; 50(40)15341-8
Determining cause of death in prostate cancer: are death certificates valid?
Penson DF, Albertsen PC, Nelson PS, Barry M, Stanford JL.
J Natl Cancer Inst. 2001 Dec 5; 23(93)1822-3
Project normal: defining normal variance in mouse gene expression.
Pritchard CC, Hsu L, Delrow J, Nelson PS.
Proc Natl Acad Sci U S A. 2001 Nov 6; 23(98)13266-71
From genomics to proteomics: techniques and applications in cancer research.
Martin DB, Nelson PS.
Trends Cell Biol. 2001 Nov; 11(11)S60-5
Prostate cancer research in the post-genome era.
Nelson PS, Stanford JL, Ostrander EA.
Epidemiol Rev. 2001; 1(23)187-90
A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression.
Akalin A, Elmore LW, Forsythe HL, Amaker BA, McCollum ED, Nelson PS, Ware JL, Holt SE.
Cancer Res. 2001 Jun 15; 12(61)4791-6
Sequence databases and microarrays as tools for identifying prostate cancer biomarkers.
Grouse LH, Munson PJ, Nelson PS.
Urology. 2001 Apr; 4 Suppl 1(57)154-9
Lin B, White JT, Ferguson C, Wang S, Vessella R, Bumgarner R, True LD, Hood L, Nelson PS.
Cancer Res. 2001 Feb 15; 4(61)1611-8
Pescadillo, a novel cell cycle regulatory protein abnormally expressed in malignant cells.
Kinoshita Y, Jarell AD, Flaman JM, Foltz G, Schuster J, Sopher BL, Irvin DK, Kanning K, Kornblum HI, Nelson PS, Hieter P, Morrison RS.
J Biol Chem. 2001 Mar 2; 9(276)6656-65
New nomenclature for the human tissue kallikrein gene family.
Diamandis EP, Yousef GM, Clements J, Ashworth LK, Yoshida S, Egelrud T, Nelson PS, Shiosaka S, Little S, Lilja H, Stenman UH, Rittenhouse HG, Wain H.
Clin Chem. 2000 Nov; 11(46)1855-8
Nelson PS, Han D, Rochon Y, Corthals GL, Lin B, Monson A, Nguyen V, Franza BR, Plymate SR, Aebersold R, Hood L.
Electrophoresis. 2000 May; 9(21)1823-31
Toll receptors: an expanding role in our understanding of human disease.
Schuster JM, Nelson PS.
J Leukoc Biol. 2000 Jun; 6(67)767-73
PART-1: a novel human prostate-specific, androgen-regulated gene that maps to chromosome 5q12.
Lin B, White JT, Ferguson C, Bumgarner R, Friedman C, Trask B, Ellis W, Lange P, Hood L, Nelson PS.
Cancer Res. 2000 Feb 15; 4(60)858-63
Negative selection: a method for obtaining low-abundance cDNAs using high-density cDNA clone arrays.
Nelson PS, Hawkins V, Schummer M, Bumgarner R, Ng WL, Ideker T, Ferguson C, Hood L.
Genet Anal. 1999 Dec 15; 6(15)209-15
The prostate expression database (PEDB): status and enhancements in 2000.
Nelson PS, Clegg N, Eroglu B, Hawkins V, Bumgarner R, Smith T, Hood L.
Nucleic Acids Res. 2000 Jan 1; 1(28)212-3
Schummer M, Ng WV, Bumgarner RE, Nelson PS, Schummer B, Bednarski DW, Hassell L, Baldwin RL, Karlan BY, Hood L.
Gene. 1999 Oct 1; 2(238)375-85
Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2.
Lin B, Ferguson C, White JT, Wang S, Vessella R, True LD, Hood L, Nelson PS.
Cancer Res. 1999 Sep 1; 17(59)4180-4
Smith TH, LaTour JV, Bochkariov D, Chaga G, Nelson PS.
Bioconjug Chem. 1999 Jul-Aug; 4(10)647-52
Monitoring gene expression profile changes in ovarian carcinomas using cDNA microarray.
Wang K, Gan L, Jeffery E, Gayle M, Gown AM, Skelly M, Nelson PS, Ng WV, Schummer M, Hood L, Mulligan J.
Gene. 1999 Mar 18; 1-2(229)101-8
Nelson PS, Gan L, Ferguson C, Moss P, Gelinas R, Hood L, Wang K.
Proc Natl Acad Sci U S A. 1999 Mar 16; 6(96)3114-9
PEDB: the Prostate Expression Database.
Hawkins V, Doll D, Bumgarner R, Smith T, Abajian C, Hood L, Nelson PS.
Nucleic Acids Res. 1999 Jan 1; 1(27)204-8
Chaudhary PM, Ferguson C, Nguyen V, Nguyen O, Massa HF, Eby M, Jasmin A, Trask BJ, Hood L, Nelson PS.
Blood. 1998 Jun 1; 11(91)4020-7
An expressed-sequence-tag database of the human prostate: sequence analysis of 1168 cDNA clones.
Nelson PS, Ng WL, Schummer M, True LD, Liu AY, Bumgarner RE, Ferguson C, Dimak A, Hood L.
Genomics. 1998 Jan 1; 1(47)12-25
Nelson PS, Plymate SR, Wang K, True LD, Ware JL, Gan L, Liu AY, Hood L.
Cancer Res. 1998 Jan 15; 2(58)232-6
Inexpensive handheld device for the construction of high-density nucleic acid arrays.
Schummer M, Ng W, Nelson PS, Bumgarner RE, Hood L.
Biotechniques. 1997 Dec; 6(23)1087-92
Cell-cell interaction in prostate gene regulation and cytodifferentiation.
Liu AY, True LD, LaTray L, Nelson PS, Ellis WJ, Vessella RL, Lange PH, Hood L, van den Engh G.
Proc Natl Acad Sci U S A. 1997 Sep 30; 20(94)10705-10
Rainbow Universal CPG: a versatile solid support for oligonucleotide synthesis.
Nelson PS, Muthini S, Vierra M, Acosta L, Smith TH.
Biotechniques. 1997 Apr; 4(22)752-6
Liu AY, Corey E, Vessella RL, Lange PH, True LD, Huang GM, Nelson PS, Hood L.
Prostate. 1997 Feb 15; 3(30)145-53
Chemoprevention for prostatic intraepithelial neoplasia.
Nelson PS, Gleason TP, Brawer MK.
Eur Urol. 1996; 2(30)269-78
Subtraction hybridization cDNA libraries.
Schweinfest CW, Nelson PS, Graber MW, Demopoulos RI, Papas TS.
Methods Mol Biol. 1995; (37)13-30
Nelson PS, Papas TS, Schweinfest CW.
Nucleic Acids Res. 1993 Feb 11; 3(21)681-6
Nelson PS, Kent M, Muthini S.
Nucleic Acids Res. 1992 Dec 11; 23(20)6253-9
Nelson PS, Sherman-Gold R, Leon R.
Nucleic Acids Res. 1989 Sep 25; 18(17)7179-86
Nelson PS, Frye RA, Liu E.
Nucleic Acids Res. 1989 Sep 25; 18(17)7187-94
Nelson PS, Streisand JB, Mulder SM, Pace NL, Stanley TH.
Anesthesiology. 1989 Apr; 4(70)616-21
Fetal growth and placental diffusing capacity in guinea pigs following long-term maternal exercise.
Nelson PS, Gilbert RD, Longo LD.
J Dev Physiol. 1983 Feb; 1(5)1-10
Distribution of maternal and fetal blood flow within cotyledons of the sheep placenta.
Power GG, Dale PS, Nelson PS.
Am J Physiol. 1981 Oct; 4(241)H486-96
Research Summary
We study several inter-related aspects of cancer biology. We seek to identify and understand the role of key somatic genomic alterations that drive cancer development, metastasis (with organ tropism), and therapy resistance. A second area of focus involves determining influences of the tumor microenvironment on cancer cell behavior. A third area of focus centers on determining the roles of hormones and nuclear hormone receptors as lineage oncogenes, with a particular emphasis on cancer of the prostate, the most common cancer affecting men.