University of Washington,
Physiology & Biophysics
Neural mechanisms of sensorimotor processing in Drosophila
Faculty Contact Information
We study neural mechanisms of sensorimotor processing in the compact nervous system of the nimble fruit fly, Drosophila. As a fly cruises through the world, her brain gathers sensory information from the external environment, which is transformed in the central nervous system, and subsequently used to guide movement and behavior. We are interested in how the nervous system implements each stage of this process— sensory coding, central integration, and motor control. To this end, we combine genetic tools with electrophysiology and 2-photon imaging to record neural activity in behaving flies.
We strive to create a lab that values and includes people with diverse backgrounds, beliefs, and experiences. We seek to recruit, support, and retain members from diverse backgrounds and groups that have historically been underrepresented in the sciences. As a team, we are committed to creating an inclusive environment where individuals feel supported and invested in their work.
The following publications were retrieved from PubMed:
Chen C, Agrawal S, Mark B, Mamiya A, Sustar A, Phelps JS, Lee WA, Dickson BJ, Card GM, Tuthill JC.
Curr Biol. 2021 Dec 6; 23(31)5163-5175.e7
Dallmann CJ, Karashchuk P, Brunton BW, Tuthill JC.
Curr Opin Physiol. 2021 Aug; (22)
Karashchuk P, Rupp KL, Dickinson ES, Walling-Bell S, Sanders E, Azim E, Brunton BW, Tuthill JC.
Cell Rep. 2021 Sep 28; 13(36)109730
Karashchuk P, Tuthill JC, Brunton BW.
Nat Methods. 2021 May; 5(18)460-462
Phelps JS, Hildebrand DGC, Graham BJ, Kuan AT, Thomas LA, Nguyen TM, Buhmann J, Azevedo AW, Sustar A, Agrawal S, Liu M, Shanny BL, Funke J, Tuthill JC, Lee WA.
Cell. 2021 Feb 4; 3(184)759-774.e18
Agrawal S, Dickinson ES, Sustar A, Gurung P, Shepherd D, Truman JW, Tuthill JC.
Elife. 2020 Dec 2; (9)
Court R, Namiki S, Armstrong JD, Börner J, Card G, Costa M, Dickinson M, Duch C, Korff W, Mann R, Merritt D, Murphey RK, Seeds AM, Shirangi T, Simpson JH, Truman JW, Tuthill JC, Williams DW, Shepherd D.
Neuron. 2020 Sep 23; 6(107)1071-1079.e2
Kuan AT, Phelps JS, Thomas LA, Nguyen TM, Han J, Chen CL, Azevedo AW, Tuthill JC, Funke J, Cloetens P, Pacureanu A, Lee WA.
Nat Neurosci. 2020 Dec; 12(23)1637-1643
Azevedo AW, Dickinson ES, Gurung P, Venkatasubramanian L, Mann RS, Tuthill JC.
Elife. 2020 Jun 3; (9)
Yan C, Wang F, Peng Y, Williams CR, Jenkins B, Wildonger J, Kim HJ, Perr JB, Vaughan JC, Kern ME, Falvo MR, O'Brien ET 3rd, Superfine R, Tuthill JC, Xiang Y, Rogers SL, Parrish JZ.
Cell Rep. 2018 Oct 23; 4(25)1051-1065.e6
Mamiya A, Gurung P, Tuthill JC.
Neuron. 2018 Nov 7; 3(100)636-650.e6
Tuthill JC, Azim E.
Curr Biol. 2018 Mar 5; 5(28)R194-R203
Tuthill JC, Wilson RI.
Curr Biol. 2016 Oct 24; 20(26)R1022-R1038
Tuthill JC, Wilson RI.
Cell. 2016 Feb 25; 5(164)1046-59
Tuthill JC, Borghuis BG.
Neuron. 2016 Feb 17; 4(89)677-80
Tuthill JC, Nern A, Rubin GM, Reiser MB.
Neuron. 2014 May 21; 4(82)887-95
Tuthill JC, Nern A, Holtz SL, Rubin GM, Reiser MB.
Neuron. 2013 Jul 10; 1(79)128-40
Tuthill JC, Chiappe ME, Reiser MB.
Proc Natl Acad Sci U S A. 2011 Jun 7; 23(108)9685-90
J Neurosci. 2009 Sep 30; 39(29)12033-4
Berón de Astrada M, Tuthill JC, Tomsic D.
J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2009 Aug; 8(195)791-8
Toward the evolutionary genomics of gametophytic divergence: patterns of transmission ratio distortion in monkeyflower (Mimulus) hybrids reveal a complex genetic basis for conspecific pollen precedence.
Fishman L, Aagaard J, Tuthill JC.
Evolution. 2008 Dec; 12(62)2958-70
Tuthill JC, Johnsen S.
J Exp Biol. 2006 May; Pt 9(209)1612-6
PubMed Collection Link
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