faculty

Young Kwon

ykwon7@uw.edu
Assistant Professor

University of Washington

Biochemistry

Cancer Biology

Cell Signaling & Cell/Environment Interactions

Developmental Biology, Stem Cells & Aging

Maintenance, remodeling, and deterioration of tissue pattern and physiology

Faculty Contact Information

Building: Health Science Building Room: J487 Box: 357350 Phone: 206-543-6517 https://sites.google.com/uw.edu/kwon-lab/members

Research Summary

Developmental process shapes sophisticated adult tissue pattern. This pattern is maintained over time and also remodeled or deteriorated by intrinsic and extrinsic factors, which affects tissue physiology and organismal health. Our overarching goal is to understand the mechanisms underlying the maintenance, remodeling, and deterioration of tissue pattern and physiology. We are particularly interested in elucidating novel ’tissue non-autonomous’ mechanisms affecting tissue integrity, metabolism, and malignant transformation by utilizing Drosophila genetics, cell biology, and biochemistry.

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Publications

The following publications were retrieved from PubMed:

Dissemination of RasV12-transformed cells requires the mechanosensitive channel Piezo.

Lee J, Cabrera AJH, Nguyen CMT, Kwon YV.

Nat Commun. 2020 Jul 16; 1(11)3568

The role of translationally controlled tumor protein in proliferation of Drosophila intestinal stem cells.

Kwon YV, Zhao B, Xu C, Lee J, Chen CL, Vinayagam A, Edgar BA, Perrimon N.

Proc Natl Acad Sci U S A. 2019 Dec 16;

Drosophila melanogaster as a Model of Muscle Degeneration Disorders.

Kreipke RE, Kwon YV, Shcherbata HR, Ruohola-Baker H.

Curr Top Dev Biol. 2017; (121)83-109

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Lab Information

Building: Health Science Building
Room: J487
Phone: 206-543-1054
https://sites.google.com/uw.edu/kwon-lab/home