faculty
Sita Kugel
skugel@fredhutch.org
Assistant Member
Fred Hutch
,Human Biology
Cancer Biology
Cell Signaling & Cell/Environment Interactions
Gene Expression, Cell Cycle & Chromosome Biology
Epigenetic reprogramming in pancreatic cancer
Faculty Contact Information
Building: Hutchinson
Room: C1-163
Box: C1-157
Phone: 206-667-3648
https://www.fredhutch.org/en/labs/profiles/kugel-sita.html
Research Summary
Although chromatin-remodeling proteins are frequently dysregulated in human cancer, little is known about how they control tumorigenesis. The central theme of our research group is use our panel of genetically engineered mouse models, patient-derived cell lines, xenografts and human tissue samples to study how the dysregulation of chromatin modifying enzymes contributes to pancreatic cancer pathogenesis and, further, whether these pathways present liabilities that could be exploited for cancer therapy.
Accepting Students For:
Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent
Lab Information
Location: Fred Hutchinson Cancer Research Center
Building: Hutchinson
Room: C1-195
Box: C1-195
Phone: 206-667-2877
https://research.fhcrc.org/kugel/en.html
Building: Hutchinson
Room: C1-195
Box: C1-195
Phone: 206-667-2877
https://research.fhcrc.org/kugel/en.html