Paul Nghiem


University of Washington

Cancer Biology

Microbiology, Infection & Immunity

Immunobiology & Immune Therapy for Merkel cell carcinoma

Faculty Contact Information

Building: Brotman / SLU Room: Room 240 Box: 358050 Phone: 206-221-2632 http://pnlab.org/

Research Summary

Merkel cell carcinoma is usually caused by the Merkel cell polyomavirus, with sunlight leading to some cases as well. This cancer is more likely to kill a patient than melanoma.
Our team (merkelcell.org) is actively engaged in developing novel immune therapies for this cancer, having performed studies that led to the first two FDA approvals for MCC. We are developing a therapeutic vaccine against MCPyV as well as exploring the basis for using DNA Damage Response inhibitors (such as an ATR inhibitor) to help patients who do not persistently benefit from anti-PD1.

DEI Statement

As a multi-racial person myself (1/2 Vietnamese, 1/4 German, 1/4 English) I grew up with uncertainty about looking and being different. It is now 100% clear to me that diversity is a strength in our society, but that supporting it is complicated and must be thoughtful, purposeful, and multi-faceted. I am passionate about providing deliberat programs and guidance to individuals who might otherwise be discriminated against or somehow impeded in reaching their full potential.

Training Summary

I believe in multi-disciplinary, collaborative science that works at ‘interfaces’ between fields to bring the greatest impact possible for science and patients.

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PubMed Collection Link

Accepting Students For:

Rotation, Summer

Lab Information

Location: University of Washington
Building: Brotman
Room: Room 242
Box: 358050
Phone: 206-221-4594