faculty

Ronald Kwon

ronkwon@uw.edu
Associate Professor

University of Washington

Computational Biology

Developmental Biology, Stem Cells & Aging

Development, disease, and regeneration

Faculty Contact Information

Building: SLU/Institute for Stem Cell and Regenerative Medicine Room: S436 Box: 358056 Phone: 206-897-5906

Research Summary

Our lab is focused on skeletal development disease and regeneration. We are understanding the genetic basis of osteoporosis, to identify new therapeutic targets to combat this massive health burden. We are also working to understand why fish are able to regenerate bony appendages following amputation, and how to mount this response in humans. The Musculoskeletal Systems Biology Lab comprises engineers, basic scientists, and clinicians. Our focus is on taking bold, innovative approaches to reverse aging-induced bone fragility, and to help realize human regenerative potential.

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Publications

The following publications were retrieved from PubMed:

The Reissner Fiber Is Highly Dynamic In Vivo and Controls Morphogenesis of the Spine.

Troutwine BR, Gontarz P, Konjikusic MJ, Minowa R, Monstad-Rios A, Sepich DS, Kwon RY, Solnica-Krezel L, Gray RS.

Curr Biol. 2020 Jun 22; 12(30)2353-2362.e3

Phenomics-Based Quantification of CRISPR-Induced Mosaicism in Zebrafish.

Watson CJ, Monstad-Rios AT, Bhimani RM, Gistelinck C, Willaert A, Coucke P, Hsu YH, Kwon RY.

Cell Syst. 2020 Mar 25; 3(10)275-286.e5

Zebrafish: An Emerging Model for Orthopedic Research.

Busse B, Galloway JL, Gray RS, Harris MP, Kwon RY.

J Orthop Res. 2020 May; 5(38)925-936

Using zebrafish to study skeletal genomics.

Kwon RY, Watson CJ, Karasik D.

Bone. 2019 Sep; (126)37-50

Zebrafish type I collagen mutants faithfully recapitulate human type I collagenopathies.

Gistelinck C, Kwon RY, Malfait F, Symoens S, Harris MP, Henke K, Hawkins MB, Fisher S, Sips P, Guillemyn B, Bek JW, Vermassen P, De Saffel H, Witten PE, Weis M, De Paepe A, Eyre DR, Willaert A, Coucke PJ.

Proc Natl Acad Sci U S A. 2018 Aug 21; 34(115)E8037-E8046

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