University of Washington
Cell Signaling & Cell/Environment Interactions
Microbiology, Infection & Immunity
Function and evolution of the plant immune system
Faculty Contact Information
The Steinbrenner lab studies the function and evolution of the plant immune system. Plants lack circulating, adaptive immune cells. Instead, individual cells must rely on a massively expanded set of germline-encoded receptor genes (e.g. leucine-rich repeat receptor kinases) to perceive attack by pests and pathogens. The lab broadly works to understand:
– How immune receptors distinguish diverse pest classes (e.g. caterpillars vs. bacteria/fungi)
– “Arms race” dynamics of pest outbreaks in nature and agriculture
– The evolution of novel immune receptors across crop plant families
Our goal is to understand plant immunity through reading, discussion, and experimentation, and then share insights with the world. As a Principal Investigator I hope to mentor the next generation of plant biologists. I aim to excite and challenge mentees and build curiosity, skill, and independence. I work to maintain an environment where trainees can build these foundations in a safe and welcoming space. I firmly believe that consistent mentorship and communication can help overcome the “hidden rules” in science, and I hope my approach will allow diverse trainees to thrive.
CIMER Entering Mentoring, Autumn 2019
The following publications were retrieved from PubMed:
Steinbrenner AD, Saldivar E, Hodges N, Guayazán-Palacios N, Chaparro AF, Schmelz EA.
Plant J. 2022 Jun; 5(110)1255-1270
Snoeck S, Guayazán-Palacios N, Steinbrenner AD.
Plant Cell. 2022 Apr 26; 5(34)1497-1513
Comparative analyses of responses to exogenous and endogenous antiherbivore elicitors enable a forward genetics approach to identify maize gene candidates mediating sensitivity to herbivore-associated molecular patterns.
Poretsky E, Ruiz M, Ahmadian N, Steinbrenner AD, Dressano K, Schmelz EA, Huffaker A.
Plant J. 2021 Dec; 5(108)1295-1316
Schultink A, Steinbrenner AD.
Curr Opin Plant Biol. 2021 Aug; (62)102089
Steinbrenner AD, Muñoz-Amatriaín M, Chaparro AF, Aguilar-Venegas JM, Lo S, Okuda S, Glauser G, Dongiovanni J, Shi D, Hall M, Crubaugh D, Holton N, Zipfel C, Abagyan R, Turlings TCJ, Close TJ, Huffaker A, Schmelz EA.
Proc Natl Acad Sci U S A. 2020 Dec 8; 49(117)31510-31518
Curr Opin Plant Biol. 2020 Aug; (56)135-146
Schultink A, Qi T, Lee A, Steinbrenner AD, Staskawicz B.
Plant J. 2017 Dec; 5(92)787-795
Goritschnig S, Steinbrenner AD, Grunwald DJ, Staskawicz BJ.
New Phytol. 2016 May; 3(210)984-96
Steinbrenner AD, Goritschnig S, Staskawicz BJ.
PLoS Pathog. 2015 Feb; 2(11)e1004665
Zhang R, Li Y, Cowley TJ, Steinbrenner AD, Phillips JM, Yount BL, Baric RS, Weiss SR.
J Virol. 2015 Apr; 7(89)3598-609
Steinbrenner AD, Goritschnig S, Krasileva KV, Schreiber KJ, Staskawicz BJ.
Cold Spring Harb Symp Quant Biol. 2012; (77)249-57
Steinbrenner AD, Gómez S, Osorio S, Fernie AR, Orians CM.
J Chem Ecol. 2011 Dec; 12(37)1294-303
Chou S, Krasileva KV, Holton JM, Steinbrenner AD, Alber T, Staskawicz BJ.
Proc Natl Acad Sci U S A. 2011 Aug 9; 32(108)13323-8