University of Washington
Cell Signaling & Cell/Environment Interactions
Microbiology, Infection & Immunity
Function and evolution of the plant immune system
Faculty Contact Information
The Steinbrenner lab studies the function and evolution of the plant immune system. Plants lack circulating, adaptive immune cells. Instead, individual cells must rely on a massively expanded set of germline-encoded receptor genes (e.g. leucine-rich repeat receptor kinases) to perceive attack by pests and pathogens. The lab broadly works to understand:
– How immune receptors distinguish diverse pest classes (e.g. caterpillars vs. bacteria/fungi)
– “Arms race” dynamics of pest outbreaks in nature and agriculture
– The evolution of novel immune receptors across crop plant families
Our lab’s goal is to be an inclusive environment where diverse lab members feel safe, welcomed, and have sense of belonging. Intentional communication and mentorship are the core of my DEI philosophy. To help set expectations and prevent misunderstanding, all lab members complete mentorship compacts upon joining according to departmental best practices https://www.biology.washington.edu/programs/graduate/mentoring-resources. Permanent lab members craft Individual Development Plans to guide their training and career goals. I help to review IDPs quarterly and revise IDPs yearly. On a weekly basis, lab presenters in our joint lab meeting share a “diversity slide” to highlight any aspect of their identity they would like to highlight. It is a great way to get to know each other as people beyond our scientific projects. I also serve on departmental and societal DEI committees to promote these values and to fight for more systemic change in academic structures.
The Erosion of Empathy (UW Professional & Organizational Development)
Entering Mentoring (CIMER) – Autumn 2019
The following publications were retrieved from PubMed:
Snoeck S, Abramson BW, Garcia AGK, Egan AN, Michael TP, Steinbrenner AD.
Elife. 2022 Nov 15; (11)
Steinbrenner AD, Saldivar E, Hodges N, Guayazán-Palacios N, Chaparro AF, Schmelz EA.
Plant J. 2022 Jun; 5(110)1255-1270
Snoeck S, Guayazán-Palacios N, Steinbrenner AD.
Plant Cell. 2022 Apr 26; 5(34)1497-1513
Comparative analyses of responses to exogenous and endogenous antiherbivore elicitors enable a forward genetics approach to identify maize gene candidates mediating sensitivity to herbivore-associated molecular patterns.
Poretsky E, Ruiz M, Ahmadian N, Steinbrenner AD, Dressano K, Schmelz EA, Huffaker A.
Plant J. 2021 Dec; 5(108)1295-1316
Schultink A, Steinbrenner AD.
Curr Opin Plant Biol. 2021 Aug; (62)102089
Steinbrenner AD, Muñoz-Amatriaín M, Chaparro AF, Aguilar-Venegas JM, Lo S, Okuda S, Glauser G, Dongiovanni J, Shi D, Hall M, Crubaugh D, Holton N, Zipfel C, Abagyan R, Turlings TCJ, Close TJ, Huffaker A, Schmelz EA.
Proc Natl Acad Sci U S A. 2020 Dec 8; 49(117)31510-31518
Curr Opin Plant Biol. 2020 Aug; (56)135-146
Schultink A, Qi T, Lee A, Steinbrenner AD, Staskawicz B.
Plant J. 2017 Dec; 5(92)787-795
Goritschnig S, Steinbrenner AD, Grunwald DJ, Staskawicz BJ.
New Phytol. 2016 May; 3(210)984-96
Steinbrenner AD, Goritschnig S, Staskawicz BJ.
PLoS Pathog. 2015 Feb; 2(11)e1004665
Zhang R, Li Y, Cowley TJ, Steinbrenner AD, Phillips JM, Yount BL, Baric RS, Weiss SR.
J Virol. 2015 Apr; 7(89)3598-609
Steinbrenner AD, Goritschnig S, Krasileva KV, Schreiber KJ, Staskawicz BJ.
Cold Spring Harb Symp Quant Biol. 2012; (77)249-57
Steinbrenner AD, Gómez S, Osorio S, Fernie AR, Orians CM.
J Chem Ecol. 2011 Dec; 12(37)1294-303
Chou S, Krasileva KV, Holton JM, Steinbrenner AD, Alber T, Staskawicz BJ.
Proc Natl Acad Sci U S A. 2011 Aug 9; 32(108)13323-8