faculty

Susan Ferguson

smfergus@uw.edu
Associate Professor

University of Washington

Neuroscience

Neural circuits that regulate drug use and addiction

Faculty Contact Information

Box: JMB-10

Research Summary

My research program uses a multi-level approach, combining molecular biology, circuit-mapping and behavioral neuroscience, to understand the role of cortico-basal ganglia-thalamic circuitry in the development of behaviors that are associated with drug reward and addiction, as well as in the processes that underlie decision-making, motivation and impulsivity. We are particularly interested in individual vulnerability to addiction and relapse.

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Publications

The following publications were retrieved from PubMed:

PQLC2 recruits the C9orf72 complex to lysosomes in response to cationic amino acid starvation.

Amick J, Tharkeshwar AK, Talaia G, Ferguson SM.

J Cell Biol. 2020 Jan 6; 1(219)

Weak membrane interactions allow Rheb to activate mTORC1 signaling without major lysosome enrichment.

Angarola B, Ferguson SM.

Mol Biol Cell. 2019 Oct 15; 22(30)2750-2760

Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis.

Roczniak-Ferguson A, Ferguson SM.

Life Sci Alliance. 2019 Oct; 5(2)

The paraventricular thalamus is a critical mediator of top-down control of cue-motivated behavior in rats.

Campus P, Covelo IR, Kim Y, Parsegian A, Kuhn BN, Lopez SA, Neumaier JF, Ferguson SM, Solberg Woods LC, Sarter M, Flagel SB.

Elife. 2019 Sep 10; (8)

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Lab Information

Location: Seattle Children's Research Institute
http://fergusonlab.weebly.com/