University of Washington
Microbiology, Infection & Immunity
Understanding viral replication in the human host
Faculty Contact Information
We’re interested in understanding the mechanisms and constraints of viral evolution in the human host. We start with observations in the clinical virology lab, working directly with clinical specimens to define how viruses react to the multitude of strong evolutionary pressures we put on them in the clinic, whether pharmaceutical or immunological. We also develop new assays that can be used in the clinical laboratory for diagnostics and clinical trials. We then use genomic, cell biology, and proteomic approaches to both identify and define mechanisms of viral evolution and host response.