University of Washington
Genetics, Genomics & Evolution
Microbiology, Infection & Immunity
Molecular evolution and mechanisms of host-pathogen interactions
Faculty Contact Information
Research in the Mitchell lab is focused on understanding basic principles that govern host-pathogen interactions that influence host immunity and pathogenesis. We are particularly interested in molecular innovations born from host-pathogen evolutionary ‘arms races.’ We combine approaches from evolution, genetics, biochemistry, immunology and microbiology to decipher mechanisms that govern innate immune recognition and other host-pathogen interactions.
For more information on specific projects, please visit the lab home page!
Science is for everyone: We are committed to creating an inclusive, safe, and equitable lab environment. We acknowledge that our institutions are flawed, and that working toward effectively combating racism, sexism, homophobia, transphobia, ableism, and other institutionalized and systemic oppressions is an important aspect of creating the scientific community we want to be a part of.
Dr. Mitchell serves on the Department of Microbiology diversity committee and the MCB DEI committee.
Building Healthy Workplaces Workshop – 2022
Inclusive teaching and mentoring workshop – 2021
The following publications were retrieved from PubMed:
Tsu BV, Beierschmitt C, Ryan AP, Agarwal R, Mitchell PS, Daugherty MD.
Elife. 2021 Jan 7; (10)
Mitchell PS, Roncaioli JL, Turcotte EA, Goers L, Chavez RA, Lee AY, Lesser CF, Rauch I, Vance RE.
Elife. 2020 Oct 19; (9)
Daskalov A, Mitchell PS, Sandstrom A, Vance RE, Glass NL.
Proc Natl Acad Sci U S A. 2020 Aug 4; 31(117)18600-18607
Herlin T, Jørgensen SE, Høst C, Mitchell PS, Christensen MH, Laustsen M, Larsen DA, Schmidt FI, Christiansen M, Mogensen TH.
Rheumatology (Oxford). 2020 Sep 1; 9(59)2334-2339
Mitchell PS, Sandstrom A, Vance RE.
Curr Opin Immunol. 2019 Oct; (60)37-45
Sandstrom A, Mitchell PS, Goers L, Mu EW, Lesser CF, Vance RE.
Science. 2019 Apr 5; 6435(364)
Chavarría-Smith J, Mitchell PS, Ho AM, Daugherty MD, Vance RE.
PLoS Pathog. 2016 Dec; 12(12)e1006052
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Building: South Lake Union Campus, F building