University of Washington
Genetics, Genomics & Evolution
Microbiology, Infection & Immunity
Molecular evolution and mechanisms of host-pathogen interactions
Faculty Contact Information
Research in the Mitchell lab is focused on understanding basic principles that govern host-pathogen interactions that influence host immunity and pathogenesis. We are particularly interested in molecular innovations born from host-pathogen evolutionary ‘arms races.’ We combine approaches from evolution, genetics, biochemistry, immunology and microbiology to decipher mechanisms that govern innate immune recognition and other host-pathogen interactions.
For more information on specific projects, please visit the lab home page!
The following publications were retrieved from PubMed:
Tsu BV, Beierschmitt C, Ryan AP, Agarwal R, Mitchell PS, Daugherty MD.
Elife. 2021 Jan 7; (10)
Mitchell PS, Roncaioli JL, Turcotte EA, Goers L, Chavez RA, Lee AY, Lesser CF, Rauch I, Vance RE.
Elife. 2020 Oct 19; (9)
Daskalov A, Mitchell PS, Sandstrom A, Vance RE, Glass NL.
Proc Natl Acad Sci U S A. 2020 Aug 4; 31(117)18600-18607
Herlin T, Jørgensen SE, Høst C, Mitchell PS, Christensen MH, Laustsen M, Larsen DA, Schmidt FI, Christiansen M, Mogensen TH.
Rheumatology (Oxford). 2020 Sep 1; 9(59)2334-2339
Mitchell PS, Sandstrom A, Vance RE.
Curr Opin Immunol. 2019 Oct; (60)37-45
Sandstrom A, Mitchell PS, Goers L, Mu EW, Lesser CF, Vance RE.
Science. 2019 Apr 5; 6435(364)
Chavarría-Smith J, Mitchell PS, Ho AM, Daugherty MD, Vance RE.
PLoS Pathog. 2016 Dec; 12(12)e1006052