Ed Lein

Research Summary

Ed Lein is a Senior Investigator at the Allen Institute for Brain Science and Affiliate Professor in the Department of Neurological Surgery. He helped create many Allen Institute brain atlases, and aims to understand developing and mature human brain cell types and circuits using single cell genomic methods. Major efforts aim to understand specialization of human brain using comparative analyses, and to understand Alzheimer’s disease phenotypes and progression. Finally, we develop tools for genetic access to specific brain cell types and development of those tools for gene therapy.