Ed Lein


Allen Institute

Developmental Biology, Stem Cells & Aging

Genetics, Genomics & Evolution


Human and comparative single cell analysis in healthy brain and Alzheimer's disease

Faculty Contact Information

Building: Allen Institute, 615 Westlake Avenue, Seattle, WA 98109 Room: 467 Box: Allen Institute, 615 Westlake Avenue, Seattle, WA Phone: 206-548-7039 https://alleninstitute.org/what-we-do/brain-science/about/team/staff-profiles/ed-lein/

Research Summary

Ed Lein is a Senior Investigator at the Allen Institute for Brain Science and Affiliate Professor in the Department of Neurological Surgery. He helped create many Allen Institute brain atlases, and aims to understand developing and mature human brain cell types and circuits using single cell genomic methods. Major efforts aim to understand specialization of human brain using comparative analyses, and to understand Alzheimer’s disease phenotypes and progression. Finally, we develop tools for genetic access to specific brain cell types and development of those tools for gene therapy.

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PubMed Collection Link

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Lab Information

Location: Allen Institute
Building: Allen Institute